ENSMUSG00000031458


Mus musculus

Features
Gene ID: ENSMUSG00000031458
  
Biological name :Coprs
  
Synonyms : Coordinator of PRMT5 and differentiation stimulator / Coprs / Q9CQ13
  
Possible biological names infered from orthology : Q9NQ92
  
Species: Mus musculus
  
Chr. number: 8
Strand: -1
Band: A1.1
Gene start: 13884794
Gene end: 13890281
  
Corresponding Affymetrix probe sets: 10577222 (MoGene1.0st)   1420113_s_at (Mouse Genome 430 2.0 Array)   1420114_s_at (Mouse Genome 430 2.0 Array)   1448971_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000148034
Ensembl peptide - ENSMUSP00000033839
NCBI entrez gene - 66423     See in Manteia.
MGI - MGI:1913673
RefSeq - NM_025556
RefSeq - XM_006508848
RefSeq Peptide - NP_079832
swissprot - A0A1B0GSQ9
swissprot - Q9CQ13
Ensembl - ENSMUSG00000031458
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 COPRSENSG00000172301Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR029289  Coordinator of PRMT5 and differentiation stimulator


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007517 muscle organ development IMP
 biological_processGO:0043985 histone H4-R3 methylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005886 plasma membrane ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042393 histone binding IEA


Pathways (from Reactome)
Pathway description
RMTs methylate histone arginines


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005670 abnormal white fat physiology "functional aberration in the connective tissue consisting of fat-storing cells and arranged in lobular groups or along minor blood vessels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Whrnhb/Whrnhb
Genetic Background: involves: BALB/c * C3H/HeH * C57BL/6J

 MP:0009118 increased white fat cell size "increase in the size of fat cells with light coloration and few mitochondria" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Whrnhb/Whrnhb
Genetic Background: involves: BALB/c * C3H/HeH * C57BL/6J

 MP:0009131 decreased white fat cell number "reduction in the number of fat cells with light coloration and few mitochondria" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Whrnhb/Whrnhb
Genetic Background: involves: BALB/c * C3H/HeH * C57BL/6J

 MP:0009305 decreased retroperitoneal fat pad weight 
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Allelic Composition: Whrnhb/Whrnhb
Genetic Background: involves: BALB/c * C3H/HeH * C57BL/6J

 MP:0011168 abnormal fat cell differentiation "abnormal or arrest of differentiation of fat-storing cells found mostly in the abdominal cavity and subcutaneous tissue of mammals" [CL:0000449, MGI:csmith]
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Allelic Composition: Whrnhb/Whrnhb
Genetic Background: involves: BALB/c * C3H/HeH * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000006728 Cdk4 / P30285 / Cyclin-dependent kinase 4 / P11802*  / complex / reaction
 ENSMUSG00000000561 Wdr77 / Q99J09 / WD repeat domain 77 / Q9BQA1*  / reaction / complex
 ENSMUSG00000070348 Ccnd1 / P25322 / G1/S-specific cyclin-D1 / P24385* / cyclin D1*  / reaction / complex
 ENSMUSG00000023110 Prmt5 / protein arginine N-methyltransferase 5 / O14744* / protein arginine methyltransferase 5*  / reaction / complex






 

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