ENSMUSG00000031754


Mus musculus

Features
Gene ID: ENSMUSG00000031754
  
Biological name :Nudt21
  
Synonyms : nudix (nucleoside diphosphate linked moiety X)-type motif 21 / Nudt21 / Q9CQF3
  
Possible biological names infered from orthology : nudix hydrolase 21 / O43809
  
Species: Mus musculus
  
Chr. number: 8
Strand: -1
Band: C5
Gene start: 94015496
Gene end: 94037031
  
Corresponding Affymetrix probe sets: 10491036 (MoGene1.0st)   10580722 (MoGene1.0st)   1417681_at (Mouse Genome 430 2.0 Array)   1428339_at (Mouse Genome 430 2.0 Array)   1437213_at (Mouse Genome 430 2.0 Array)   1455966_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000034204
Ensembl peptide - ENSMUSP00000148597
Ensembl peptide - ENSMUSP00000148500
Ensembl peptide - ENSMUSP00000148485
NCBI entrez gene - 68219     See in Manteia.
MGI - MGI:1915469
RefSeq - NM_026623
RefSeq Peptide - NP_080899
swissprot - A0A1D5RLT7
swissprot - A0A1D5RLS2
swissprot - A0A1D5RM23
swissprot - Q9CQF3
Ensembl - ENSMUSG00000031754
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nudt21ENSDARG00000003153Danio rerio
 NUDT21ENSGALG00000003084Gallus gallus
 NUDT21ENSG00000167005Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000086  NUDIX hydrolase domain
 IPR015797  NUDIX hydrolase-like domain superfamily
 IPR016706  Cleavage/polyadenylation specificity factor subunit 5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006378 mRNA polyadenylation IEA
 biological_processGO:0006379 mRNA cleavage ISO
 biological_processGO:0006397 mRNA processing ISO
 biological_processGO:0010608 posttranscriptional regulation of gene expression IMP
 biological_processGO:0031439 positive regulation of mRNA cleavage IEA
 biological_processGO:0031442 positive regulation of mRNA 3"-end processing IEA
 biological_processGO:0051262 protein tetramerization IEA
 biological_processGO:0051290 protein heterotetramerization IEA
 biological_processGO:0098789 pre-mRNA cleavage required for polyadenylation IEA
 biological_processGO:1900365 positive regulation of mRNA polyadenylation IEA
 biological_processGO:1990120 messenger ribonucleoprotein complex assembly IEA
 biological_processGO:2000738 positive regulation of stem cell differentiation IMP
 biological_processGO:2000975 positive regulation of pro-B cell differentiation IMP
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005847 mRNA cleavage and polyadenylation specificity factor complex IEA
 cellular_componentGO:0005849 mRNA cleavage factor complex IEA
 cellular_componentGO:0016604 nuclear body IEA
 cellular_componentGO:0042382 paraspeckles IEA
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0003723 RNA binding ISO
 molecular_functionGO:0003729 mRNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0017091 AU-rich element binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0042826 histone deacetylase binding IEA


Pathways (from Reactome)
Pathway description
Cleavage of Growing Transcript in the Termination Region
mRNA Splicing - Major Pathway
mRNA 3-end processing
Processing of Intronless Pre-mRNAs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000027079 Clp1 / Q99LI9 / Polyribonucleotide 5-hydroxyl-kinase Clp1 / Q92989* / cleavage and polyadenylation factor I subunit 1*  / complex
 ENSMUSG00000034820 Cpsf7 / Q8BTV2 / Cleavage and polyadenylation specificity factor subunit 7 / Q8N684* / cleavage and polyadenylation specific factor 7*  / complex
 ENSMUSG00000041328 Pcf11 / PCF11 cleavage and polyadenylation factor subunit / O94913*  / complex






 

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