ENSMUSG00000032372


Mus musculus

Features
Gene ID: ENSMUSG00000032372
  
Biological name :Plscr2
  
Synonyms : Phospholipid scramblase 2 / Plscr2 / Q9DCW2
  
Possible biological names infered from orthology : O15162 / phospholipid scramblase 1 / PLSCR1 / Q9NRY7
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: E3.3
Gene start: 92275602
Gene end: 92297752
  
Corresponding Affymetrix probe sets: 10587799 (MoGene1.0st)   1448961_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000136481
Ensembl peptide - ENSMUSP00000034932
Ensembl peptide - ENSMUSP00000108667
Ensembl peptide - ENSMUSP00000119104
NCBI entrez gene - 18828     See in Manteia.
MGI - MGI:1270860
RefSeq - XM_011242676
RefSeq - NM_001195084
RefSeq - NM_008880
RefSeq - XM_006510857
RefSeq - XM_011242675
RefSeq Peptide - NP_032906
RefSeq Peptide - NP_001182013
swissprot - D3Z7J3
swissprot - Q9DCW2
swissprot - D3Z2S8
Ensembl - ENSMUSG00000032372
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-71m22.1ENSDARG00000058638Danio rerio
 si:ch211-71m22.3ENSDARG00000079075Danio rerio
 si:ch211-71m22.5ENSDARG00000091266Danio rerio
 si:ch73-170d6.4ENSDARG00000102460Danio rerio
 si:ch73-206p6.1ENSDARG00000077468Danio rerio
 ENSGALG00000006805Gallus gallus
 O15162ENSG00000188313Homo sapiens
 PLSCR2ENSG00000163746Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Plscr1 / Q9JJ00 / Phospholipid scramblase 1 / O15162* / PLSCR2* / Q9NRY7* / phospholipid scramblase 2*ENSMUSG0000003236975
1700057G04Rik / RIKEN cDNA 1700057G04 gene / PLSCR1* / PLSCR2* / Q9NRY7* / O15162* / phospholipid scramblase 1* / phospholipid scramblase 2*ENSMUSG0000007413944
Plscr5 / phospholipid scramblase family member 5 / A0PG75*ENSMUSG0000009565443
Plscr3 / Q9JIZ9 / Phospholipid scramblase 3 / Q9NRY6*ENSMUSG0000001946143
P58196 / Plscr4 / Phospholipid scramblase 4 / Q9NRQ2*ENSMUSG0000003237742


Protein motifs (from Interpro)
Interpro ID Name
 IPR005552  Scramblase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0017121 phospholipid scrambling IEA
 biological_processGO:0071222 cellular response to lipopolysaccharide IEP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017124 SH3 domain binding IEA
 molecular_functionGO:0017128 phospholipid scramblase activity IBA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000480 increased number of ribs "greater than normal numbers of the pairs of bony structures that make up the body wall" [MeSH:National Library of Medicine - Medical Subject Headings, 2003]
Show

Allelic Composition: Pdgfrbtm1b(EUCOMM)Hmgu/Pdgfrb+
Genetic Background: C57BL/6N-Pdgfrbtm1b(EUCOMM)Hmgu/H

 MP:0000562 polydactyly "greater than 5 digits on one or more autopods" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Pdgfrbtm1b(EUCOMM)Hmgu/Pdgfrb+
Genetic Background: C57BL/6N-Pdgfrbtm1b(EUCOMM)Hmgu/H

 MP:0010169 decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number "a reduction in the number of the CD4-positive, CD25-positive T cell subset which regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release" [ISBN:0781735149]
Show

Allelic Composition: Pdgfrbtm1b(EUCOMM)Hmgu/Pdgfrb+
Genetic Background: C57BL/6N-Pdgfrbtm1b(EUCOMM)Hmgu/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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