ENSMUSG00000032396


Mus musculus

Features
Gene ID: ENSMUSG00000032396
  
Biological name :Dis3l
  
Synonyms : Dis3l / DIS3-like exonuclease 1 / Q8C0S1
  
Possible biological names infered from orthology : DIS3 like exosome 3-5 exoribonuclease / Q8TF46
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: C
Gene start: 64306756
Gene end: 64341288
  
Corresponding Affymetrix probe sets: 10594460 (MoGene1.0st)   1437737_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000109522
Ensembl peptide - ENSMUSP00000115236
Ensembl peptide - ENSMUSP00000129772
Ensembl peptide - ENSMUSP00000063830
Ensembl peptide - ENSMUSP00000113503
NCBI entrez gene - 213550     See in Manteia.
MGI - MGI:2143272
RefSeq - XM_011242700
RefSeq - NM_001001295
RefSeq - NM_001177784
RefSeq - NM_172519
RefSeq - XM_006510982
RefSeq - XM_006510983
RefSeq Peptide - NP_766107
RefSeq Peptide - NP_001001295
RefSeq Peptide - NP_001171255
swissprot - Q8C0S1
swissprot - D3YUD6
Ensembl - ENSMUSG00000032396
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dis3lENSDARG00000053200Danio rerio
 DIS3LENSGALG00000007643Gallus gallus
 DIS3LENSG00000166938Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Dis3 / Q9CSH3 / Exosome complex exonuclease RRP44 / Q9Y2L1* / DIS3 homolog, exosome endoribonuclease and 3-5 exoribonuclease*ENSMUSG0000003316632
Dis3l2 / Q8CI75 / DIS3-like exonuclease 2 / Q8IYB7* / DIS3 like 3-5 exoribonuclease 2*ENSMUSG0000005333322


Protein motifs (from Interpro)
Interpro ID Name
 IPR012340  Nucleic acid-binding, OB-fold
 IPR022966  Ribonuclease II/R, conserved site
 IPR031192  DIS3-like exonuclease 1
 IPR033770  Exosome complex exonuclease RRP44, S1 domain
 IPR033771  Rrp44-like cold shock domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006364 rRNA processing IBA
 biological_processGO:0006401 RNA catabolic process IBA
 biological_processGO:0016075 rRNA catabolic process ISO
 biological_processGO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic IEA
 cellular_componentGO:0000177 cytoplasmic exosome (RNase complex) IEA
 cellular_componentGO:0000178 exosome (RNase complex) IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 molecular_functionGO:0000175 3"-5"-exoribonuclease activity IBA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004527 exonuclease activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0019899 enzyme binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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