ENSMUSG00000033060


Mus musculus

Features
Gene ID: ENSMUSG00000033060
  
Biological name :Lmo7
  
Synonyms : Lmo7 / Mus musculus LIM domain only 7 (Lmo7), transcript variant 2, mRNA.
  
Possible biological names infered from orthology : LIM domain 7 / Q8WWI1
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: E2.3
Gene start: 101729957
Gene end: 101934710
  
Corresponding Affymetrix probe sets: 10416800 (MoGene1.0st)   1455056_at (Mouse Genome 430 2.0 Array)   1458453_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000124349
Ensembl peptide - ENSMUSP00000124300
Ensembl peptide - ENSMUSP00000124605
Ensembl peptide - ENSMUSP00000125465
Ensembl peptide - ENSMUSP00000097910
Ensembl peptide - ENSMUSP00000123706
NCBI entrez gene - 380928     See in Manteia.
MGI - MGI:1353586
RefSeq - XM_017316071
RefSeq - XM_006519188
RefSeq - XM_006519189
RefSeq - XM_006519190
RefSeq - XM_006519191
RefSeq - XM_006519192
RefSeq - XM_017316068
RefSeq - XM_017316069
RefSeq - XM_017316070
RefSeq - NM_001347628
RefSeq - NM_201529
RefSeq - XM_006519176
RefSeq - XM_006519178
RefSeq - XM_006519179
RefSeq - XM_006519180
RefSeq - XM_006519181
RefSeq - XM_006519182
RefSeq - XM_006519183
RefSeq - XM_006519184
RefSeq - XM_006519185
RefSeq - XM_006519186
RefSeq - XM_006519187
RefSeq Peptide - NP_001334557
RefSeq Peptide - NP_963287
swissprot - F6VG99
swissprot - E9PYF4
swissprot - E9PYI7
swissprot - E0CZD8
swissprot - Q3UPW3
swissprot - F6TFN2
Ensembl - ENSMUSG00000033060
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lmo7aENSDARG00000004930Danio rerio
 LMO7ENSGALG00000016920Gallus gallus
 LMO7ENSG00000136153Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Limch1 / Q3UH68 / LIM and calponin homology domains-containing protein 1 / Q9UPQ0* / LIM and calponin homology domains 1*ENSMUSG0000003773619


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR001715  Calponin homology domain
 IPR001781  Zinc finger, LIM-type
 IPR003096  Smooth muscle protein/calponin
 IPR029978  LIM domain only protein 7
 IPR031865  Domain of unknown function DUF4757
 IPR036034  PDZ superfamily
 IPR036872  CH domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0023051 regulation of signaling IEA
 biological_processGO:0030155 regulation of cell adhesion IEA
 biological_processGO:0098609 cell-cell adhesion IEA
 cellular_componentGO:0005913 cell-cell adherens junction IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity ISO
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0042805 actinin binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Terttm1Rdp/Terttm1Rdp,Trp53tm1Tyj/Trp53+
Genetic Background: B6.Cg-Trp53tm1Tyj Terttm1Rdp

 MP:0002027 lung adenocarcinoma "malignant neoplasm of epithelial cells in the lung" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:18542]
Show

Allelic Composition: Muc2M1Btlr/Muc2+
Genetic Background: C57BL/6J-Muc2M1Btlr

Allelic Composition: Lmo7tm1Miyo/Lmo7+
Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2

Allelic Composition: Lmo7tm1Miyo/Lmo7tm1Miyo
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0003084 abnormal skeletal muscle fiber morphology "anomalous structure of the skeletal muscle fibers, the large multinucleated cells that make up the skeletal muscles" [smb:Susan M. Bello, Mouse Genome Informatics Curator, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Terttm1Rdp/Terttm1Rdp,Trp53tm1Tyj/Trp53+
Genetic Background: B6.Cg-Trp53tm1Tyj Terttm1Rdp

 MP:0003728 abnormal photoreceptor layer "malformation/anomalous structure of the photoreceptor layer" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Terttm1Rdp/Terttm1Rdp,Trp53tm1Tyj/Trp53+
Genetic Background: B6.Cg-Trp53tm1Tyj Terttm1Rdp

 MP:0003729 abnormal photoreceptor outer segments "malformation/anomalous structure of the photoreceptor layer which contains stacks of membranous discs that are rich in the visual pigment rhodopsin " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Terttm1Rdp/Terttm1Rdp,Trp53tm1Tyj/Trp53+
Genetic Background: B6.Cg-Trp53tm1Tyj Terttm1Rdp

 MP:0003730 abnormal photoreceptor inner segments "malformation/anomalous structure of the photoreceptor layer which contains the machinery of the cell (mitochondria, golgi, endoplasmic reticulum, etc)" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Terttm1Rdp/Terttm1Rdp,Trp53tm1Tyj/Trp53+
Genetic Background: B6.Cg-Trp53tm1Tyj Terttm1Rdp

 MP:0003731 abnormal outer nuclear layer morphology "malformation/anomalous structure of the retinal layer that contains the nuclei and cell bodies of rods and cones" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Terttm1Rdp/Terttm1Rdp,Trp53tm1Tyj/Trp53+
Genetic Background: B6.Cg-Trp53tm1Tyj Terttm1Rdp

 MP:0003998 decreased thermal nociceptive threshold "a lower than average point at which thermal pain sensation is first detectable" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Terttm1Rdp/Terttm1Rdp,Trp53tm1Tyj/Trp53+
Genetic Background: B6.Cg-Trp53tm1Tyj Terttm1Rdp

 MP:0005103 abnormal retinal pigmentation "anomalous coloring of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Terttm1Rdp/Terttm1Rdp,Trp53tm1Tyj/Trp53+
Genetic Background: B6.Cg-Trp53tm1Tyj Terttm1Rdp

 MP:0006382 abnormal lung epithelium morphology "any structural anomaly of the epithelial layer of the lung" [MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Muc2M1Btlr/Muc2+
Genetic Background: C57BL/6J-Muc2M1Btlr

Allelic Composition: Lmo7tm1Miyo/Lmo7tm1Miyo
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Terttm1Rdp/Terttm1Rdp,Trp53tm1Tyj/Trp53+
Genetic Background: B6.Cg-Trp53tm1Tyj Terttm1Rdp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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