ENSMUSG00000034292


Mus musculus

Features
Gene ID: ENSMUSG00000034292
  
Biological name :Traf3ip1
  
Synonyms : Q149C2 / TRAF3 interacting protein 1 / Traf3ip1
  
Possible biological names infered from orthology : Q8TDR0
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: D
Gene start: 91494647
Gene end: 91529307
  
Corresponding Affymetrix probe sets: 10348600 (MoGene1.0st)   1452887_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000042391
Ensembl peptide - ENSMUSP00000140151
NCBI entrez gene - 74019     See in Manteia.
MGI - MGI:1921269
RefSeq - XM_006529898
RefSeq - NM_028718
RefSeq - XM_006529896
RefSeq - XM_006529897
RefSeq Peptide - NP_082994
swissprot - A0A087WQD8
swissprot - Q149C2
Ensembl - ENSMUSG00000034292
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 traf3ip1ENSDARG00000010300Danio rerio
 TRAF3IP1ENSGALG00000004236Gallus gallus
 Q8TDR0ENSG00000204104Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR018799  TRAF3-interacting protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISO
 biological_processGO:0001738 morphogenesis of a polarized epithelium IMP
 biological_processGO:0001822 kidney development IEA
 biological_processGO:0001933 negative regulation of protein phosphorylation IEA
 biological_processGO:0021532 neural tube patterning IMP
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0031076 embryonic camera-type eye development IMP
 biological_processGO:0031333 negative regulation of protein complex assembly IEA
 biological_processGO:0032480 negative regulation of type I interferon production IEA
 biological_processGO:0032688 negative regulation of interferon-beta production IMP
 biological_processGO:0035050 embryonic heart tube development IMP
 biological_processGO:0036342 post-anal tail morphogenesis IMP
 biological_processGO:0042073 intraciliary transport IC
 biological_processGO:0042532 negative regulation of tyrosine phosphorylation of STAT protein ISO
 biological_processGO:0042733 embryonic digit morphogenesis IMP
 biological_processGO:0050687 negative regulation of defense response to virus IEA
 biological_processGO:0051101 regulation of DNA binding ISO
 biological_processGO:0060271 cilium assembly IMP
 biological_processGO:0070507 regulation of microtubule cytoskeleton organization IEA
 biological_processGO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005929 cilium TAS
 cellular_componentGO:0005930 axoneme IDA
 cellular_componentGO:0015630 microtubule cytoskeleton ISO
 cellular_componentGO:0030992 intraciliary transport particle B IDA
 cellular_componentGO:0035869 ciliary transition zone IEA
 cellular_componentGO:0036064 ciliary basal body IDA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0097542 ciliary tip IEA
 cellular_componentGO:0097546 ciliary base IEA
 molecular_functionGO:0005102 signaling receptor binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008017 microtubule binding ISO
 molecular_functionGO:0015631 tubulin binding ISO


Pathways (from Reactome)
Pathway description
Intraflagellar transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000562 polydactyly "greater than 5 digits on one or more autopods" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Creb1tm1.1Berd/Creb1tm1.1Berd,Dmdmdx/Y
Genetic Background: B.Cg-Creb1tm1.1Berd Dmdmdx

 MP:0001297 microphthalmia "reduced average size of the eyes" [J:18048]
Show

Allelic Composition: Creb1tm1.1Berd/Creb1tm1.1Berd,Dmdmdx/Y
Genetic Background: B.Cg-Creb1tm1.1Berd Dmdmdx

 MP:0002151 abnormal neural tube morphology/development "anomalous structure of or development of the embryonic neural tube resulting in structural anomaly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Creb1tm1.1Berd/Creb1tm1.1Berd,Dmdmdx/Y
Genetic Background: B.Cg-Creb1tm1.1Berd Dmdmdx

 MP:0003051 curly tail "a loop or corkscrew-like curl in the tail" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Creb1tm1.1Berd/Creb1tm1.1Berd,Dmdmdx/Y
Genetic Background: B.Cg-Creb1tm1.1Berd Dmdmdx

 MP:0003861 abnormal nervous system development "impaired or altered growth of the components of the nervous system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Creb1tm1.1Berd/Creb1tm1.1Berd,Dmdmdx/Y
Genetic Background: B.Cg-Creb1tm1.1Berd Dmdmdx

 MP:0004132 absent embryonic cilia "absence of cilia on the cells of the embryonic node " [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
Show

Allelic Composition: Creb1tm1.1Berd/Creb1tm1.1Berd,Dmdmdx/Y
Genetic Background: B.Cg-Creb1tm1.1Berd Dmdmdx

 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
Show

Allelic Composition: Creb1tm1.1Berd/Creb1tm1.1Berd,Dmdmdx/Y
Genetic Background: B.Cg-Creb1tm1.1Berd Dmdmdx

 MP:0012270 cardiac edema "abnormal accumulation of fluid in the interstitial tissues and cavities of the body due to impaired cardiac function or congestive heart failure; usually characterized by increased venous and capillary pressures and often associated with renal sodium retention" [MGI:anna]
Show

Allelic Composition: Creb1tm1.1Berd/Creb1tm1.1Berd,Dmdmdx/Y
Genetic Background: B.Cg-Creb1tm1.1Berd Dmdmdx

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000001105 Ift20 / Q61025 / Intraflagellar transport / Q8IY31* / intraflagellar transport 20*  / reaction / complex






 

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