| MP:0000026 | abnormal inner ear morphology | "malformation or malfunction of any components of the labyrinth, including the semicircular canals, vestibule and cochlea" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:1776] |
Show
Allelic Composition: Mitfmi-ce/Mitfmi-ce
Genetic Background: DBA/2N
|
| MP:0000031 | abnormal cochlea morphology | "any anomaly, deformity, malformation, impairment or dysfunction of the cochlea" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator, J:21484] |
Show
Allelic Composition: MitfMi-wh/MitfMi-wh
Genetic Background: involves: C57BL * DBA
Allelic Composition: MitfMi/MitfMi
Genetic Background: Not Specified
Allelic Composition: MitfMi/Mitf+
Genetic Background: Not Specified
|
| MP:0000048 | abnormal stria vascularis | "anomalous structure of the layer of highly vascularized pigmented granular cells on the outer wall of the cochlear duct" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: MitfMi-wh/MitfMi-wh
Genetic Background: involves: C57BL * DBA
Allelic Composition: MitfMi/MitfMi
Genetic Background: Not Specified
Allelic Composition: MitfMi/Mitf+
Genetic Background: Not Specified
Allelic Composition: Mitfmi-bw/Mitfmi-bw
Genetic Background: C3H
|
| MP:0000067 | osteopetrosis | "excessive formation of dense trabecular bone and excessive calcified cartilage formation; may lead to anemia and extramedullary hematopoiesis " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings, 2003] |
Show
Allelic Composition: Lmnatm2Stw/Lmnatm2Stw
Genetic Background: involves: 129S1/Sv
Allelic Composition: Mitfmi-vga9/Mitfmi-vga9,Tfe3tm1Est/Tfe3tm1Est
Genetic Background: either: (involves: 129/Sv * 129S1/Sv * C57BL/6 * CBA) or (involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA)
Allelic Composition: Mitfmi-ew/Mitfmi-ew,Tfe3tm1Est/Tfe3tm1Est
Genetic Background: either: (involves: 129/Sv * 129S1/Sv * C57BL/6Bn * NAW) or (involves: 129S1/Sv * C57BL/6Bn * C57BL/6J * NAW)
Allelic Composition: MitfMi-wh/MitfMi-wh,Tfe3tm1Est/Tfe3tm1Est
Genetic Background: either: (involves: 129/Sv * 129S1/Sv * C57BL * DBA) or (involves: 129S1/Sv * C57BL * C57BL/6J * DBA)
Allelic Composition: MitfMi/MitfMi
Genetic Background: Not Specified
Allelic Composition: Mitfmi-di/Mitfmi-di
Genetic Background: (PT x C3H/HeH)F1
Allelic Composition: MitfMi-Or/MitfMi-Or
Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: MitfMi/MitfMi
Genetic Background: involves: C57BL/6J
Allelic Composition: Mitfmi-ew/Mitfmi-ew
Genetic Background: involves: C57BL/6Bn * NAW
Allelic Composition: MitfMi/MitfMi,Tfectm1Est/Tfectm1Est
Genetic Background: either: (involves: 129/Sv * 129S1/Sv * C57BL/6J) or (involves: 129S1/Sv * C57BL/6J)
Allelic Composition: MitfMi/MitfMi,Tfe3tm1Est/Tfe3tm1Est
Genetic Background: either: (involves: 129/Sv * 129S1/Sv * C57BL/6J) or (involves: 129S1/Sv * C57BL/6J)
Allelic Composition: MitfMi-wh/MitfMi-wh,Tfe3tm1Est/Tfe3tm1Est,Tfectm1Est/Tfectm1Est
Genetic Background: either: (involves: 129/Sv * 129S1/Sv * C57BL * DBA) or (involves: 129S1/Sv * C57BL * C57BL/6J * DBA)
Allelic Composition: Mitfmi-ew/Mitfmi-ew,Tfe3tm1Est/Tfe3+
Genetic Background: either: (involves: 129/Sv * 129S1/Sv * C57BL/6Bn * NAW) or (involves: 129S1/Sv * C57BL/6Bn * C57BL/6J * NAW)
|
| MP:0000121 | failure of tooth eruption | "inability of the teeth to grow into the oral cavity" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61295] |
Show
Allelic Composition: Lmnatm2Stw/Lmnatm2Stw
Genetic Background: involves: 129S1/Sv
Allelic Composition: MitfMi/MitfMi
Genetic Background: Not Specified
Allelic Composition: MitfMi-Or/MitfMi-Or
Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: MitfMi/MitfMi
Genetic Background: involves: C57BL/6J
|
| MP:0000133 | abnormal long bone metaphysis morphology | "malformed conical section of bone between the epiphysis and diaphysis of the long bones" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:61295] |
Show
Allelic Composition: Mitfmi-tg/Mitfmi-tg
Genetic Background: B6.Cg-Mitfmi-tg
|
| MP:0000336 | decreased mast cell number | "fewer than expected number of the granulated cells found in most tissues and which contain large amounts of histamine and heparin in granules" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: MitfMi/MitfMi
Genetic Background: Not Specified
|
| MP:0000371 | diluted coat color | "a coat color that appears lighter in intensity or paler than normal" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: MitfRorp/Mitf+
Genetic Background: involves: BALB/cAnN * C3H/HeN
Allelic Composition: Mitfmi-enu5/Mitf+
Genetic Background: involves: 102 * C3H/El
Allelic Composition: Mitfmi-Mhdabcc2/Mitf+
Genetic Background: C3HeB/FeJ-Mitfmi-Mhdabcc2/Ieg
Allelic Composition: MitfMi-wh/Mitf+
Genetic Background: involves: C57BL * DBA
Allelic Composition: MitfMi-b/Mitf+
Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Mitfmi-vit/Mitfmi-vit
Genetic Background: C57BL/6J-Mitfmi-vit
Allelic Composition: Mitfmi-vit/Mitfmi-vit
Genetic Background: C57BL/6J-Mitfmi-vit/J
Allelic Composition: MitfMi-wh/Mitf+,Myo5ad/Myo5ad
Genetic Background: involves: C57BL * DBA
Allelic Composition: MitfMi-wh/Mitfmi-sp
Genetic Background: B6.Cg-MitfMi-wh/Mitfmi-sp/J
Allelic Composition: MitfMi-Or/Mitf+
Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Mitftm4Arnh/MitfMi-wh
Genetic Background: involves: 129S6/SvEvTac * C57BL * C57BL/6N * DBA
Allelic Composition: Mitftm5Arnh/MitfMi-wh
Genetic Background: involves: 129S6/SvEvTac * C57BL * C57BL/6N * DBA
Allelic Composition: Mitftm6Arnh/MitfMi-wh
Genetic Background: involves: 129S6/SvEvTac * C57BL * C57BL/6N * DBA
Allelic Composition: Mitftm7Arnh/MitfMi-wh
Genetic Background: involves: 129S6/SvEvTac * C57BL * C57BL/6N * DBA
Allelic Composition: Mitftm4.1Arnh/MitfMi-wh
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL * C57BL/6N * DBA
|
| MP:0000372 | irregular coat pigmentation | "uneven coloration of the hair" [J:65030] |
Show
Allelic Composition: MitfMi-H/Mitf+
Genetic Background: involves: BALB/cAnN * C3H/HeN
Allelic Composition: Mitfmi-enu122/Mitfmi-enu122
Genetic Background: involves: 102 * C3H
Allelic Composition: Mitftm1Arnh/Mitftm1Arnh
Genetic Background: involves: 129S1/Sv * C57BL/6
Allelic Composition: Mitfmi-x39/Mitfmi-x39
Genetic Background: involves: 102 * C3H
Allelic Composition: Mitftm6Arnh/Mitfmi-vga9
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6N * CBA
Allelic Composition: Mitftm7Arnh/Mitfmi-vga9
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6N * CBA
|
| MP:0000373 | belly spot | "the appearance of a round area of white fur on the belly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Mitfmi-enu5/Mitfmi-enu5
Genetic Background: involves: 102 * C3H/El
Allelic Composition: Mitfmi-Mhdabcc2/Mitf+
Genetic Background: C3HeB/FeJ-Mitfmi-Mhdabcc2/Ieg
Allelic Composition: MitfMi/Mitf+
Genetic Background: Not Specified
Allelic Composition: MitfMi-ws/Mitf+
Genetic Background: involves: C57BL/6
Allelic Composition: MitfMi-Or/Mitf+
Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Mitfmi-x39/Mitf+
Genetic Background: involves: 102 * C3H
Allelic Composition: Mitftm4Arnh/Mitftm4Arnh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6N
Allelic Composition: Mitftm6Arnh/Mitftm6Arnh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6N
Allelic Composition: Mitftm7Arnh/Mitftm7Arnh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6N
Allelic Composition: Mitftm5Arnh/Mitfmi-vga9
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6N * CBA
Allelic Composition: Mitftm5.1Arnh/MitfMi-wh
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL * C57BL/6N * DBA
Allelic Composition: Mitftm7.1Arnh/MitfMi-wh
Genetic Background: involves: 129S6/SvEvTac * C57BL * C57BL/6N * DBA
Allelic Composition: Mitftm5.1Arnh/Mitftm5.1Arnh,Kittm1Alf/Kit+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * 129S6/SvEvTac * C57BL/6N
Allelic Composition: Mitftm7.1Arnh/Mitftm7.1Arnh,Kittm1Alf/Kit+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * 129S6/SvEvTac * C57BL/6N
|
| MP:0000377 | abnormal hair follicle | "malformed invagination of the epidermis from which the hair shaft develops" [J:65031] |
Show
Allelic Composition: Arntltm1Weit/Arntltm1Weit
Genetic Background: involves: 129S4/SvJae * C57BL/6
|
| MP:0000394 | absent melanin granules in hair follicle | "missing pigment polymers in the hair follicles" [J:18378] |
Show
Allelic Composition: Pax1Un-s/Pax1+
Genetic Background: CC57BR/MvY
|
| MP:0000689 | abnormal spleen morphology | "atypical structure of the organ that functions to filter blood and to store red corpuscles and platelets" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:27463] |
Show
Allelic Composition: Fosl2tm2Wag/Fosl2tm2Wag,Tg(COL2A1-cre)1Wag/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
|
| MP:0001004 | abnormal photoreceptor morphology | "structural or developmental anomaly of the receptors sensitive to light " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Mitfmi-di/Mitfmi-di
Genetic Background: (PT x C3H/HeH)F1
|
| MP:0001189 | absent skin pigmentation | "lack of pigmentation of the skin" [J:53370] |
Show
Allelic Composition: H2-T23tm3Cant/H2-T23tm3Cant,Tg(Tcra2D2,Tcrb2D2)1Kuch/?
Genetic Background: involves: 129S6/SvEvTac * C57BL/6
|
| MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
Show
Allelic Composition: Mitfmi-vga9/Mitfmi-vga9,Tfe3tm1Est/Tfe3tm1Est
Genetic Background: either: (involves: 129/Sv * 129S1/Sv * C57BL/6 * CBA) or (involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA)
Allelic Composition: MitfMi-wh/MitfMi-wh,Tfe3tm1Est/Tfe3tm1Est
Genetic Background: either: (involves: 129/Sv * 129S1/Sv * C57BL * DBA) or (involves: 129S1/Sv * C57BL * C57BL/6J * DBA)
|
| MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
Show
Allelic Composition: Tnfsf4Ath1-A/J/Tnfsf4Ath1-A/J,Ath2A/J/Ath2A/J
Genetic Background: involves: C3H/HeJ * C57BL/6J
Allelic Composition: MitfMi/MitfMi
Genetic Background: involves: C57BL/6J
|
| MP:0001286 | abnormal eye development | "malformation or arrest of differentiation of the visual organ" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:49840] |
Show
Allelic Composition: Parp1tm1Zqw/Parp1tm1Zqw
Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Mitfmi-ce/Mitfmi-ce
Genetic Background: DBA/2N
Allelic Composition: MitfMi-ws/MitfMi-ws
Genetic Background: involves: C57BL/6
|
| MP:0001293 | anophthalmia | "congenital absence of all tissues of the eyes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CML, J:71979] |
Show
Allelic Composition: MitfMi-H/MitfMi-H
Genetic Background: involves: BALB/cAnN * C3H/HeN
Allelic Composition: MitfMi-Or/MitfMi-Or
Genetic Background: involves: 101/Rl * C3H/Rl
|
| MP:0001297 | microphthalmia | "reduced average size of the eyes" [J:18048] |
Show
Allelic Composition: Lmnatm2Stw/Lmnatm2Stw
Genetic Background: involves: 129S1/Sv
Allelic Composition: MitfMi-wh/Mitfmi-x
Genetic Background: NZB/Mac
Allelic Composition: Mitfmi-enu5/Mitfmi-enu5
Genetic Background: involves: 102 * C3H/El
Allelic Composition: Mitfmi-Mhdabcc2/Mitfmi-Mhdabcc2
Genetic Background: C3HeB/FeJ-Mitfmi-Mhdabcc2/Ieg
Allelic Composition: MitfMi-wh/MitfMi-wh
Genetic Background: involves: C57BL * DBA
Allelic Composition: Mitfmi-vga9/Mitfmi-vga9,Tfe3tm1Est/Tfe3tm1Est
Genetic Background: either: (involves: 129/Sv * 129S1/Sv * C57BL/6 * CBA) or (involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA)
Allelic Composition: Mitfmi-ew/Mitfmi-ew,Tfe3tm1Est/Tfe3tm1Est
Genetic Background: either: (involves: 129/Sv * 129S1/Sv * C57BL/6Bn * NAW) or (involves: 129S1/Sv * C57BL/6Bn * C57BL/6J * NAW)
Allelic Composition: MitfMi-wh/MitfMi-wh,Tfe3tm1Est/Tfe3tm1Est
Genetic Background: either: (involves: 129/Sv * 129S1/Sv * C57BL * DBA) or (involves: 129S1/Sv * C57BL * C57BL/6J * DBA)
Allelic Composition: MitfMi-wh/MitfMi-wh,Tfectm1Est/Tfectm1Est
Genetic Background: either: (involves: 129/Sv * 129S1/Sv * C57BL * DBA) or (involves: 129S1/Sv * C57BL * C57BL/6J * DBA)
Allelic Composition: MitfMi/MitfMi
Genetic Background: Not Specified
Allelic Composition: Mitfmi-di/Mitfmi-di
Genetic Background: (PT x C3H/HeH)F1
Allelic Composition: Mitfmi-ce/Mitfmi-ce
Genetic Background: DBA/2N
Allelic Composition: Mitfmi-enu122/Mitfmi-enu122
Genetic Background: involves: 102 * C3H
Allelic Composition: MitfMi-ws/MitfMi-ws
Genetic Background: involves: C57BL/6
Allelic Composition: MitfMi-wh/MitfMi-wh
Genetic Background: B6.Cg-MitfMi-wh
Allelic Composition: Mitfmi-tg/Mitfmi-tg
Genetic Background: involves: C3H/HeNCrl * C57BL/6NCrl
Allelic Composition: MitfMi-Or/MitfMi-Or
Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Mitfmi-rw/Mitfmi-rw
Genetic Background: CBA/J
Allelic Composition: Mitfmi-x39/Mitfmi-x39
Genetic Background: involves: 102 * C3H
Allelic Composition: Mitfmi-enu198/Mitfmi-enu198
Genetic Background: involves: 102 * C3H
Allelic Composition: Mitfmi-vga9/Mitfmi-vga9
Genetic Background: involves: C57BL/6 * CBA
Allelic Composition: MitfMi/MitfMi
Genetic Background: involves: C57BL/6J
Allelic Composition: MitfMi-wh/MitfMi-wh
Genetic Background: involves: C57BL * C57BL/6J * DBA
Allelic Composition: Mitfmi-ew/Mitfmi-ew
Genetic Background: involves: C57BL/6Bn * NAW
Allelic Composition: MitfMi/MitfMi,Tfectm1Est/Tfectm1Est
Genetic Background: either: (involves: 129/Sv * 129S1/Sv * C57BL/6J) or (involves: 129S1/Sv * C57BL/6J)
Allelic Composition: MitfMi/MitfMi,Tfe3tm1Est/Tfe3tm1Est
Genetic Background: either: (involves: 129/Sv * 129S1/Sv * C57BL/6J) or (involves: 129S1/Sv * C57BL/6J)
Allelic Composition: MitfMi-wh/MitfMi-wh,Tfe3tm1Est/Tfe3tm1Est,Tfectm1Est/Tfectm1Est
Genetic Background: either: (involves: 129/Sv * 129S1/Sv * C57BL * DBA) or (involves: 129S1/Sv * C57BL * C57BL/6J * DBA)
Allelic Composition: MitfMi-wh/MitfMi-wh,Tfebtm1Est/Tfeb+
Genetic Background: involves: 129S1/Sv * C57BL * C57BL/6J * DBA
Allelic Composition: Mitfmi-ew/Mitfmi-ew,Tfe3tm1Est/Tfe3+
Genetic Background: either: (involves: 129/Sv * 129S1/Sv * C57BL/6Bn * NAW) or (involves: 129S1/Sv * C57BL/6Bn * C57BL/6J * NAW)
Allelic Composition: MitfMi/MitfMi-J
Genetic Background: involves: C3HeB/Fe * C57BL/6J * C57BL/10J
|
| MP:0001303 | abnormal lens morphology | "malformed transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203] |
Show
Allelic Composition: Fgfr1tm1Jpa/Fgfr1tm1Jpa,Fgfr2tm1Dor/Fgfr2tm1Dor,Tg(Hoxb7-cre)5526Cmb/0
Genetic Background: involves: FVB/N
Allelic Composition: MitfMi-Mee/MitfMi-Mee
Genetic Background: involves: C57BL/6 * FVB
|
| MP:0001304 | cataracts | "complete or partial opacity of the lens" [J:65031] |
Show
Allelic Composition: Mitfmi-ce/Mitfmi-ce
Genetic Background: DBA/2N
|
| MP:0001322 | abnormal iris morphology | "structural anomaly of the adjustable membrane, composed of the stroma and pigmented epithelium, located just in front of the crystalline lens within the eye" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: MitfMi-H/Mitf+
Genetic Background: involves: BALB/cAnN * C3H/HeN
|
| MP:0001324 | abnormal eye pigmentation | "change in the normal black pigmentation of the eye to another color, or lack of color" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Lmnatm2Stw/Lmnatm2Stw
Genetic Background: involves: 129S1/Sv
Allelic Composition: Mitfmi-ce/Mitfmi-ce
Genetic Background: DBA/2N
Allelic Composition: MitfMi-b/MitfMi-b
Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: MitfMi-b/Mitf+
Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: MitfMi-ws/MitfMi-ws
Genetic Background: involves: C57BL/6
Allelic Composition: Mitfmi-rw/Mitfmi-rw
Genetic Background: CBA/J
|
| MP:0001325 | abnormal retina morphology | "structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: MitfRorp/MitfRorp
Genetic Background: involves: BALB/cAnN * C3H/HeN
Allelic Composition: MitfRorp/Mitf+
Genetic Background: involves: BALB/cAnN * C3H/HeN
Allelic Composition: MitfMi-b/MitfMi-b
Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: MitfMi-Mee/MitfMi-Mee
Genetic Background: involves: C57BL/6 * FVB
|
| MP:0001326 | retinal degeneration | "pathological change in the thin layer of neural tissue lining the back of the eyeball, which contains visual receptors and can result in the impairment or cessation of retinal neural function" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, NMF:Stephanie Pretel, Neuroscience Mutagenesis Facility Curator] |
Show
Allelic Composition: MitfMi-b/MitfMi-b
Genetic Background: involves: 101/Rl * C3H/Rl
|
| MP:0001333 | absent optic nerve | "absence of the second cranial nerve which is responsible for conveying visual information from the retina to the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: MitfMi/MitfMi
Genetic Background: Not Specified
|
| MP:0001340 | abnormal eyelid morphology | "malformation of the skin folds covering the front of the eyeball" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Lmnatm2Stw/Lmnatm2Stw
Genetic Background: involves: 129S1/Sv
|
| MP:0001382 | abnormal nursing | "females do not nurse pups or nurse pups infrequently" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Tgfb3tm1Doe/Tgfb3tm1Doe
Genetic Background: either: (involves: 129/Sv * 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * CF-1)
Allelic Composition: Mitfmi-Mhdabcc2/Mitfmi-Mhdabcc2
Genetic Background: C3HeB/FeJ-Mitfmi-Mhdabcc2/Ieg
|
| MP:0001485 | abnormal pinna reflex | "failure to respond to an auditory stimulus by a characteristic ear twitch " [J:64900] |
Show
Allelic Composition: Tgfb3tm1Doe/Tgfb3tm1Doe
Genetic Background: either: (involves: 129/Sv * 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * CF-1)
|
| MP:0001541 | abnormal osteoclast function | "reduced ability or inability of osteoclasts to absorb and remove osseous tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58795] |
Show
Allelic Composition: MitfMi-Or/MitfMi-Or
Genetic Background: involves: 101/Rl * C3H/Rl
|
| MP:0001921 | reduced fertility | "diminished ability to produce live offspring" [J:65030] |
Show
Allelic Composition: Tnfsf4Ath1-A/J/Tnfsf4Ath1-A/J,Ath2A/J/Ath2A/J
Genetic Background: involves: C3H/HeJ * C57BL/6J
|
| MP:0001925 | male infertility | "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409] |
Show
Allelic Composition: Lmnatm2Stw/Lmnatm2Stw
Genetic Background: involves: 129S1/Sv
Allelic Composition: Mitfmi-enu5/Mitfmi-enu5
Genetic Background: involves: 102 * C3H/El
Allelic Composition: Mitfmi-Mhdabcc2/Mitfmi-Mhdabcc2
Genetic Background: C3HeB/FeJ-Mitfmi-Mhdabcc2/Ieg
|
| MP:0001926 | female infertility | "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193] |
Show
Allelic Composition: Lmnatm2Stw/Lmnatm2Stw
Genetic Background: involves: 129S1/Sv
Allelic Composition: Mitfmi-enu5/Mitfmi-enu5
Genetic Background: involves: 102 * C3H/El
Allelic Composition: Mitfmi-Mhdabcc2/Mitfmi-Mhdabcc2
Genetic Background: C3HeB/FeJ-Mitfmi-Mhdabcc2/Ieg
Allelic Composition: MitfMi-Or/MitfMi-Or
Genetic Background: involves: 101/Rl * C3H/Rl
|
| MP:0001927 | abnormal oestrous cycle (sensu Rodentia) | "failure of or aberrant timing of the sexual cycle of female animals" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193] |
Show
Allelic Composition: Fgfr1tm1Jpa/Fgfr1tm1Jpa,Fgfr2tm1Dor/Fgfr2tm1Dor,Tg(Hoxb7-cre)5526Cmb/0
Genetic Background: involves: FVB/N
|
| MP:0001935 | reduced litter size | "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: MitfMi-wh/MitfMi-wh
Genetic Background: involves: C57BL * DBA
|
| MP:0001963 | abnormal hearing | "anomaly in the ability to receive auditory stimuli" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Ccr9tm1Ccb/Ccr9tm1Ccb
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
| MP:0002075 | abnormal coat color | "irregular or unusual pigmentation pattern of the hair in relation to control animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Lmnatm2Stw/Lmnatm2Stw
Genetic Background: involves: 129S1/Sv
Allelic Composition: MitfMi-H/MitfMi-H
Genetic Background: involves: BALB/cAnN * C3H/HeN
Allelic Composition: MitfMi-H/Mitf+
Genetic Background: involves: BALB/cAnN * C3H/HeN
Allelic Composition: MitfMi-H/MitfRorp
Genetic Background: involves: BALB/cAnN * C3H/HeN
Allelic Composition: MitfRorp/MitfRorp
Genetic Background: involves: BALB/cAnN * C3H/HeN
Allelic Composition: MitfRorp/Mitf+
Genetic Background: involves: BALB/cAnN * C3H/HeN
Allelic Composition: MitfMi/Mitf+
Genetic Background: Not Specified
Allelic Composition: MitfMi-ws/Mitf+
Genetic Background: involves: C57BL/6
Allelic Composition: MitfMi-ws/MitfMi-ws
Genetic Background: involves: C57BL/6
Allelic Composition: Mitfmi-vit/Mitfmi-vit,Tg(KRT14-Edn3)1Takk/?
Genetic Background: involves: C57BL/6 * C57BL/6J * DBA/2
Allelic Composition: MitfMi-wh/Mitfmi-sp
Genetic Background: B6.Cg-MitfMi-wh/Mitfmi-sp/J
Allelic Composition: MitfMi-b/MitfMi-wh
Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Mitfmi-rw/Mitfmi-rw
Genetic Background: CBA/J
Allelic Composition: Mitftm5.1Arnh/Mitftm5.1Arnh,Kittm1Alf/Kit+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * 129S6/SvEvTac * C57BL/6N
|
| MP:0002082 | postnatal lethality | "premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Parp1tm1Zqw/Parp1tm1Zqw
Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: MitfMi/MitfMi
Genetic Background: involves: C57BL/6J
|
| MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Mitfmi-tg/Mitfmi-tg
Genetic Background: B6.Cg-Mitfmi-tg
|
| MP:0002092 | abnormal eye morphology | "abnormal development of the eye tissues resulting in morphological abnormality or abnormal structure of the visual system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: MitfMi-H/MitfMi-H
Genetic Background: involves: BALB/cAnN * C3H/HeN
Allelic Composition: MitfMi-ws/MitfMi-ws
Genetic Background: involves: C57BL/6
Allelic Composition: MitfMi/Mitf+,Vsx2or-J/Vsx2or-J
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: MitfMi/Mitf+,Vsx2tm1.1Itl/Vsx2tm1.1Itl
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac
Allelic Composition: MitfMi/Mitf+,Vsx2tm1.1Eml/Vsx2tm1.1Eml
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
|
| MP:0002095 | abnormal skin pigmentation | "variation of skin color or complexion" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: MitfMi-H/MitfMi-H
Genetic Background: involves: BALB/cAnN * C3H/HeN
|
| MP:0002161 | abnormal fertility/fecundity | "reduced ability or inability to produce live offspring" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Fgfr1tm1Jpa/Fgfr1tm1Jpa,Fgfr2tm1Dor/Fgfr2tm1Dor,Tg(Hoxb7-cre)5526Cmb/0
Genetic Background: involves: FVB/N
|
| MP:0002169 | no phenotype detected | "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Mitfmi-vga9/Mitfmi-vga9,Pax6Sey-Neu/Pax6+
Genetic Background: involves: C57BL/6 * CBA
|
| MP:0002356 | abnormal spleen red pulp morphology | "anomalous structure of the area of the spleen that screens and eliminates defective or foreign cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology:ISBN 0-397-51047-0] |
Show
Allelic Composition: Mitfmi-di/Mitfmi-di
Genetic Background: (PT x C3H/HeH)F1
|
| MP:0002357 | abnormal spleen white pulp morphology | "anomalous structure or formation of the splenic area consisting of lymph nodules and diffuse lymphatic tissue" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7] |
Show
Allelic Composition: Mitfmi-di/Mitfmi-di
Genetic Background: (PT x C3H/HeH)F1
|
| MP:0002359 | abnormal spleen germinal center morphology | "anomalous structure or formation of the area of the spleen in which activated follicles are located" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology:ISBN 0-397-51047-0] |
Show
Allelic Composition: Mitfmi-di/Mitfmi-di
Genetic Background: (PT x C3H/HeH)F1
|
| MP:0002423 | abnormal mast cell physiology | "anomalous response of the granulated cells found in most tissues and which contain large amounts of histamine and heparin in granules" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Mitfmi-tg/Mitf+
Genetic Background: involves: C3H/HeNCrl * C57BL/6NCrl
Allelic Composition: Mitfmi-tg/Mitfmi-tg
Genetic Background: B6.Cg-Mitfmi-tg
|
| MP:0002546 | mydriasis | "dilation of one or both pupils" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: MitfMi-H/MitfRorp
Genetic Background: involves: BALB/cAnN * C3H/HeN
Allelic Composition: MitfRorp/MitfRorp
Genetic Background: involves: BALB/cAnN * C3H/HeN
|
| MP:0002622 | abnormal cochlear hair cell morphology | "malformation of the sensory epithelial cells of the cochlea; these cells are in synaptic contact with the auditory nerve" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: MitfMi-wh/MitfMi-wh
Genetic Background: involves: C57BL * DBA
Allelic Composition: MitfMi/MitfMi
Genetic Background: Not Specified
Allelic Composition: MitfMi/Mitf+
Genetic Background: Not Specified
Allelic Composition: Mitfmi-ce/Mitfmi-ce
Genetic Background: DBA/2N
|
| MP:0002697 | abnormal eye size | "anomalous bulk of the organ of vision" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: MitfMi-ws/MitfMi-ws
Genetic Background: involves: C57BL/6
Allelic Composition: Mitfmi-rw/Mitfmi-rw
Genetic Background: CBA/J
Allelic Composition: MitfMi/Mitf+,Vsx2or-J/Vsx2or-J
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: MitfMi/Mitf+,Vsx2tm1.1Itl/Vsx2tm1.1Itl
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac
Allelic Composition: MitfMi/Mitf+,Vsx2tm1.1Eml/Vsx2tm1.1Eml
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
|
| MP:0002699 | abnormal vitreous body | "anomalies of the transparent, semigelatinous substance that fills the cavity behind the crystalline lens of the eye and in front of the retina" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Mitfmi-di/Mitfmi-di
Genetic Background: (PT x C3H/HeH)F1
|
| MP:0002864 | abnormal ocular fundus morphology | "malformation of the posterior concave interior of the eye, consisting of the retina, the choroid, the posterior segment of the sclera, the optic disk, and blood vessels, visible by an ophthalmoscope" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: MitfMi-H/MitfRorp
Genetic Background: involves: BALB/cAnN * C3H/HeN
|
| MP:0002877 | abnormal melanocyte morphology | "malformation of the cells that produce pigment " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Mitfmi-vit/Mitfmi-vit,Tg(KRT14-Edn3)1Takk/?
Genetic Background: involves: C57BL/6 * C57BL/6J * DBA/2
Allelic Composition: Mitfmi-vit/Mitfmi-vit
Genetic Background: C57BL/6J-Mitfmi-vit
Allelic Composition: Mitfmi-tg/Mitfmi-tg
Genetic Background: involves: C3H/HeNCrl * C57BL/6NCrl
Allelic Composition: Mitfmi-tg/Mitf+
Genetic Background: involves: C3H/HeNCrl * C57BL/6NCrl
Allelic Composition: Mitftm5.1Arnh/Mitftm5.1Arnh,Kittm1Alf/Kit+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * 129S6/SvEvTac * C57BL/6N
|
| MP:0002938 | white spotting | "the appearance of patches of white fur" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Mitfmi-enu5/Mitf+
Genetic Background: involves: 102 * C3H/El
Allelic Composition: Mitfmi-Mhdabcc2/Mitf+
Genetic Background: C3HeB/FeJ-Mitfmi-Mhdabcc2/Ieg
Allelic Composition: MitfMi-wh/Mitf+
Genetic Background: involves: C57BL * DBA
Allelic Composition: MitfMi/Mitf+
Genetic Background: Not Specified
Allelic Composition: Mitfmi-bws/Mitfmi-bws
Genetic Background: BKS.Cg-m+/+Leprdb
Allelic Composition: MitfMi-ws/Mitf+
Genetic Background: involves: C57BL/6
Allelic Composition: Mitfmi-vit/Mitfmi-vit,Tg(KRT14-Edn3)1Takk/?
Genetic Background: involves: C57BL/6 * C57BL/6J * DBA/2
Allelic Composition: Mitfmi-vit/Mitfmi-vit
Genetic Background: C57BL/6J-Mitfmi-vit
Allelic Composition: MitfMi-wh/Mitfmi-sp
Genetic Background: B6.Cg-MitfMi-wh/Mitfmi-sp/J
Allelic Composition: Mitftm4Arnh/MitfMi-wh
Genetic Background: involves: 129S6/SvEvTac * C57BL * C57BL/6N * DBA
Allelic Composition: Mitftm5Arnh/MitfMi-wh
Genetic Background: involves: 129S6/SvEvTac * C57BL * C57BL/6N * DBA
Allelic Composition: Mitftm6Arnh/MitfMi-wh
Genetic Background: involves: 129S6/SvEvTac * C57BL * C57BL/6N * DBA
Allelic Composition: Mitftm7Arnh/MitfMi-wh
Genetic Background: involves: 129S6/SvEvTac * C57BL * C57BL/6N * DBA
Allelic Composition: Mitftm4.1Arnh/MitfMi-wh
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL * C57BL/6N * DBA
|
| MP:0002939 | head spot | "the appearance of a round area of white fur on the head" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Mitfmi-enu5/Mitf+
Genetic Background: involves: 102 * C3H/El
Allelic Composition: Mitfmi-Mhdabcc2/Mitf+
Genetic Background: C3HeB/FeJ-Mitfmi-Mhdabcc2/Ieg
Allelic Composition: MitfMi/Mitf+
Genetic Background: Not Specified
Allelic Composition: MitfMi-Or/Mitf+
Genetic Background: involves: 101/Rl * C3H/Rl
|
| MP:0002940 | variable body spotting | "the appearance of patches of white fur at random on the coat" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Lmnatm2Stw/Lmnatm2Stw
Genetic Background: involves: 129S1/Sv
Allelic Composition: MitfMi-b/MitfMi-wh
Genetic Background: involves: 101/Rl * C3H/Rl
|
| MP:0003053 | delayed tooth eruption | "postponed onset of the growth of the teeth out of the gums" [pvb:Pierre Vanden Borre, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Mitfmi-vga9/Mitfmi-vga9,Tfe3tm1Est/Tfe3tm1Est
Genetic Background: either: (involves: 129/Sv * 129S1/Sv * C57BL/6 * CBA) or (involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA)
Allelic Composition: Mitfmi-ew/Mitfmi-ew,Tfe3tm1Est/Tfe3tm1Est
Genetic Background: either: (involves: 129/Sv * 129S1/Sv * C57BL/6Bn * NAW) or (involves: 129S1/Sv * C57BL/6Bn * C57BL/6J * NAW)
|
| MP:0003055 | abnormal epiphyseal plate morphology | "malformed or absent cartilagenous center of ossification on the long bones permitting growth of the bone in both directions during development" [MeSH:National Library of Medicine - Medical Subject Headings, 2003] |
Show
Allelic Composition: MitfMi-Or/MitfMi-Or
Genetic Background: involves: 101/Rl * C3H/Rl
|
| MP:0003099 | retinal detachment | "detachment of the retina from the underlying inner wall of the eye, often from tension of the vitreous; may occur with aging or as a result of trauma" [ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator, J:83544] |
Show
Allelic Composition: Mitfmi-vit/Mitfmi-vit
Genetic Background: C57BL/6J-Mitfmi-vit
|
| MP:0003136 | yellow coat color | "amount and distribution of yellow pigment (phaeomelanin) relative to black or brown pigment (eumelanin) is increased compared to wild-type agouti" [llw2:Linda L. Washburn, Mouse Genome Informatics Curator] |
Show
Allelic Composition: MitfMi-wh/Mitfmi-sp
Genetic Background: B6.Cg-MitfMi-wh/Mitfmi-sp/J
|
| MP:0003169 | abnormal scala media morphology | "any malformation or absence of the division of the spiral canal of the cochlea that contains the organ of Corti (the neuroepithelial receptor organ for hearing)" [J:23837, J:46972, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
Show
Allelic Composition: MitfMi/MitfMi
Genetic Background: Not Specified
|
| MP:0003171 | phenotypic reversion | "reverse mutation to wild-type phenotype from a previously characterized mutant phenotype" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
Show
Allelic Composition: MitfMi/Mitftm1Arnh
Genetic Background: involves: 129S1/Sv * C57BL/6
|
| MP:0003408 | increased width of hypertrophic chondrocyte zone | "increased width of cartilage cell matrix layer " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: MitfMi-Or/MitfMi-Or
Genetic Background: involves: 101/Rl * C3H/Rl
|
| MP:0003730 | abnormal photoreceptor inner segments | "malformation/anomalous structure of the photoreceptor layer which contains the machinery of the cell (mitochondria, golgi, endoplasmic reticulum, etc)" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Mitfmi-di/Mitfmi-di
Genetic Background: (PT x C3H/HeH)F1
|
| MP:0003798 | abnormal Harderian gland pigmentation | "anomalous coloring of the sebaceous gland located behind the eyeball in the orbit that excretes fluid that facilitates movement of the third eyelid" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
Show
Allelic Composition: MitfMi-b/MitfMi-b
Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: MitfMi-b/Mitf+
Genetic Background: involves: 101/Rl * C3H/Rl
|
| MP:0004021 | abnormal rod electrophysiology | "anomaly in the function of dark adapted vision mediated by the rods" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Mitfmi-vit/Mitfmi-vit
Genetic Background: C57BL/6J-Mitfmi-vit
|
| MP:0004201 | fetal growth retardation | "slow or limited development during the fetal period (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Mitfmi-vit/Mitfmi-vit
Genetic Background: C57BL/6J-Mitfmi-vit
|
| MP:0004268 | abnormal optic stalk morphology | "any structural anomaly of the narrow, proximal portion of the optic vesicle which connects the embryonic eye and forebrain" [ISBN:0-914294-08-3 "Gray s Anatomy"] |
Show
Allelic Composition: MitfMi/MitfMi
Genetic Background: Not Specified
Allelic Composition: MitfMi-wh/MitfMi-wh
Genetic Background: B6.Cg-MitfMi-wh
|
| MP:0004269 | abnormal optic cup morphology | "any structural anomaly of double walled stuctured formed by expansion and invagination of the distal end of the optic vesicle that develops into the pigmented and sensory layers of the retina while the mouth of the optic cup eventually forms the pupil of the eye" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: MitfMi/MitfMi
Genetic Background: Not Specified
Allelic Composition: MitfMi-wh/MitfMi-wh
Genetic Background: B6.Cg-MitfMi-wh
Allelic Composition: MitfMi-Mee/MitfMi-Mee
Genetic Background: involves: C57BL/6 * FVB
|
| MP:0004364 | thin stria vascularis | "reduced thickness of the stratified, secretory epithelium which lines the upper part of the cochlear spiral ligament and maintains potassium ion homeostasis in the endolymph" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Mitfmi-bw/Mitfmi-bw
Genetic Background: C3H
Allelic Composition: Mitfmi-ce/Mitfmi-ce
Genetic Background: DBA/2N
|
| MP:0004381 | abnormal hair follicle melanocyte morphology | "any structural anomaly of the cells that produce pigment in the hair follicles" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Mitfmi-tg/Mitfmi-tg
Genetic Background: involves: C3H/HeNCrl * C57BL/6NCrl
Allelic Composition: Mitftm5.1Arnh/Mitftm5.1Arnh,Kittm1Alf/Kit+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * 129S6/SvEvTac * C57BL/6N
|
| MP:0004686 | decreased length of long bones | "reduced end-to-end length of the several elongated bones of the extremities" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: MitfMi-Or/MitfMi-Or
Genetic Background: involves: 101/Rl * C3H/Rl
|
| MP:0004982 | abnormal osteoclast morphology | "any structural anomaly of the bone resorpting cells that remove bone tissue by degrading the mineralized matrix" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Mitfmi-vga9/Mitfmi-vga9,Tfe3tm1Est/Tfe3tm1Est
Genetic Background: either: (involves: 129/Sv * 129S1/Sv * C57BL/6 * CBA) or (involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA)
Allelic Composition: Mitfmi-ew/Mitfmi-ew,Tfe3tm1Est/Tfe3tm1Est
Genetic Background: either: (involves: 129/Sv * 129S1/Sv * C57BL/6Bn * NAW) or (involves: 129S1/Sv * C57BL/6Bn * C57BL/6J * NAW)
Allelic Composition: MitfMi/MitfMi
Genetic Background: Not Specified
Allelic Composition: MitfMi-Or/MitfMi-Or
Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: MitfMi/MitfMi
Genetic Background: involves: C57BL/6J
Allelic Composition: MitfMi/MitfMi,Tfe3tm1Est/Tfe3tm1Est
Genetic Background: either: (involves: 129/Sv * 129S1/Sv * C57BL/6J) or (involves: 129S1/Sv * C57BL/6J)
|
| MP:0004984 | increased osteoclast cell number | "greater than average number of the bone resorpting cells that remove bone tissue by degrading the mineralized matrix" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: MitfMi/MitfMi
Genetic Background: Not Specified
Allelic Composition: MitfMi-Or/MitfMi-Or
Genetic Background: involves: 101/Rl * C3H/Rl
|
| MP:0004985 | decreased osteoclast cell number | "reduced number of the bone resorpting cells that remove bone tissue by degrading the mineralized matrix" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: MitfMi-Or/MitfMi-Or
Genetic Background: involves: 101/Rl * C3H/Rl
|
| MP:0005098 | abnormal choroid morphology | "anomalous structure of the thin, highly vascularized membrane covering most of the posterior of the eye between the retina and the sclera" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: MitfMi/MitfMi
Genetic Background: Not Specified
Allelic Composition: MitfMi-wh/MitfMi-wh
Genetic Background: B6.Cg-MitfMi-wh
|
| MP:0005099 | abnormal ciliary body morphology | "structural anomaly of the thickened portion of the vascular tunic, which lies between the choroid and the iris" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: MitfMi/MitfMi
Genetic Background: Not Specified
|
| MP:0005100 | abnormal choroid pigmentation | "anomalous coloring of the thin, highly vascularized membrane covering most of the posterior of the eye between the retina and the sclera" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: MitfMi-b/MitfMi-b
Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: MitfMi-b/Mitf+
Genetic Background: involves: 101/Rl * C3H/Rl
|
| MP:0005102 | abnormal iris pigmentation | "anomalous coloring of the adjustable membrane, composed of the stroma and pigmented epithelium, located just in front of the crystalline lens within the eye" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Lmnatm2Stw/Lmnatm2Stw
Genetic Background: involves: 129S1/Sv
Allelic Composition: MitfMi-H/MitfRorp
Genetic Background: involves: BALB/cAnN * C3H/HeN
Allelic Composition: MitfRorp/MitfRorp
Genetic Background: involves: BALB/cAnN * C3H/HeN
Allelic Composition: MitfMi-wh/Mitf+
Genetic Background: involves: C57BL * DBA
Allelic Composition: Mitfmi-vit/Mitfmi-vit
Genetic Background: C57BL/6J-Mitfmi-vit/J
Allelic Composition: MitfMi-Mee/MitfMi-Mee
Genetic Background: involves: C57BL/6 * FVB
Allelic Composition: Mitfmi-tg/Mitfmi-tg
Genetic Background: involves: C3H/HeNCrl * C57BL/6NCrl
|
| MP:0005103 | abnormal retinal pigmentation | "anomalous coloring of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: MitfMi/MitfMi
Genetic Background: Not Specified
Allelic Composition: Mitfmi-enu122/Mitf+
Genetic Background: involves: 102 * C3H
Allelic Composition: Mitfmi-vit/Mitfmi-vit
Genetic Background: C57BL/6J-Mitfmi-vit
Allelic Composition: MitfMi-wh/MitfMi-wh
Genetic Background: B6.Cg-MitfMi-wh
Allelic Composition: MitfMi-Mee/?
Genetic Background: involves: C57BL/6 * CAST * FVB
Allelic Composition: MitfMi-Mee/MitfMi-Mee
Genetic Background: involves: C57BL/6 * FVB
Allelic Composition: MitfMi-Mee/Mitf+
Genetic Background: involves: C57BL/6 * FVB
|
| MP:0005171 | lack of coat pigmentation | "fur is devoid of coloration and appears white " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:83500] |
Show
Allelic Composition: Lmnatm2Stw/Lmnatm2Stw
Genetic Background: involves: 129S1/Sv
Allelic Composition: MitfMi-H/MitfMi-H
Genetic Background: involves: BALB/cAnN * C3H/HeN
Allelic Composition: MitfMi-H/MitfRorp
Genetic Background: involves: BALB/cAnN * C3H/HeN
Allelic Composition: MitfRorp/MitfRorp
Genetic Background: involves: BALB/cAnN * C3H/HeN
Allelic Composition: Mitfmi-enu5/Mitfmi-enu5
Genetic Background: involves: 102 * C3H/El
Allelic Composition: Mitfmi-Mhdabcc2/Mitfmi-Mhdabcc2
Genetic Background: C3HeB/FeJ-Mitfmi-Mhdabcc2/Ieg
Allelic Composition: MitfMi-wh/MitfMi-wh
Genetic Background: involves: C57BL * DBA
Allelic Composition: Mitfmi-vga9/Mitfmi-vga9,Tfe3tm1Est/Tfe3tm1Est
Genetic Background: either: (involves: 129/Sv * 129S1/Sv * C57BL/6 * CBA) or (involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA)
Allelic Composition: Mitfmi-ew/Mitfmi-ew,Tfe3tm1Est/Tfe3tm1Est
Genetic Background: either: (involves: 129/Sv * 129S1/Sv * C57BL/6Bn * NAW) or (involves: 129S1/Sv * C57BL/6Bn * C57BL/6J * NAW)
Allelic Composition: MitfMi-wh/MitfMi-wh,Tfe3tm1Est/Tfe3tm1Est
Genetic Background: either: (involves: 129/Sv * 129S1/Sv * C57BL * DBA) or (involves: 129S1/Sv * C57BL * C57BL/6J * DBA)
Allelic Composition: MitfMi-wh/MitfMi-wh,Tfectm1Est/Tfectm1Est
Genetic Background: either: (involves: 129/Sv * 129S1/Sv * C57BL * DBA) or (involves: 129S1/Sv * C57BL * C57BL/6J * DBA)
Allelic Composition: MitfMi/MitfMi
Genetic Background: Not Specified
Allelic Composition: Mitfmi-bw/Mitfmi-bw
Genetic Background: C3H
Allelic Composition: Mitfmi-di/Mitfmi-di
Genetic Background: (PT x C3H/HeH)F1
Allelic Composition: MitfMi-b/MitfMi-b
Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: MitfMi-ws/MitfMi-ws
Genetic Background: involves: C57BL/6
Allelic Composition: Mitfmi-vit/Mitfmi-vit
Genetic Background: C57BL/6J-Mitfmi-vit
Allelic Composition: Mitftm1Arnh/Mitftm1Arnh
Genetic Background: involves: 129S1/Sv * C57BL/6
Allelic Composition: Mitfmi-ew/Mitftm1Arnh
Genetic Background: involves: 129S1/Sv * C57BL/6 * NAW
Allelic Composition: Mitfmi-vga9/Mitftm1Arnh
Genetic Background: involves: 129S1/Sv * C3H/He * C57BL/6
Allelic Composition: MitfMi/Mitftm1Arnh
Genetic Background: involves: 129S1/Sv * C57BL/6
Allelic Composition: MitfMi-Mee/MitfMi-Mee
Genetic Background: involves: C57BL/6 * FVB
Allelic Composition: MitfMi/Mitfmi-sp
Genetic Background: B6.Cg-MitfMi/Mitfmi-sp
Allelic Composition: Mitfmi-tg/Mitfmi-tg
Genetic Background: involves: C3H/HeNCrl * C57BL/6NCrl
Allelic Composition: Mitfmi-tg/Mitfmi-tg
Genetic Background: B6.Cg-Mitfmi-tg
Allelic Composition: MitfMi-Or/MitfMi-Or
Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: MitfMi-b/MitfMi-Or
Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Mitfmi-x39/Mitfmi-x39
Genetic Background: involves: 102 * C3H
Allelic Composition: Mitfmi-enu198/Mitfmi-enu198
Genetic Background: involves: 102 * C3H
Allelic Composition: Mitfmi-vga9/Mitfmi-vga9
Genetic Background: involves: C57BL/6 * CBA
Allelic Composition: MitfMi/MitfMi
Genetic Background: involves: C57BL/6J
Allelic Composition: MitfMi-wh/MitfMi-wh
Genetic Background: involves: C57BL * C57BL/6J * DBA
Allelic Composition: Mitfmi-ew/Mitfmi-ew
Genetic Background: involves: C57BL/6Bn * NAW
Allelic Composition: MitfMi/MitfMi,Tfectm1Est/Tfectm1Est
Genetic Background: either: (involves: 129/Sv * 129S1/Sv * C57BL/6J) or (involves: 129S1/Sv * C57BL/6J)
Allelic Composition: MitfMi/MitfMi,Tfe3tm1Est/Tfe3tm1Est
Genetic Background: either: (involves: 129/Sv * 129S1/Sv * C57BL/6J) or (involves: 129S1/Sv * C57BL/6J)
Allelic Composition: MitfMi-wh/MitfMi-wh,Tfe3tm1Est/Tfe3tm1Est,Tfectm1Est/Tfectm1Est
Genetic Background: either: (involves: 129/Sv * 129S1/Sv * C57BL * DBA) or (involves: 129S1/Sv * C57BL * C57BL/6J * DBA)
Allelic Composition: MitfMi-wh/MitfMi-wh,Tfebtm1Est/Tfeb+
Genetic Background: involves: 129S1/Sv * C57BL * C57BL/6J * DBA
Allelic Composition: Mitfmi-ew/Mitfmi-ew,Tfe3tm1Est/Tfe3+
Genetic Background: either: (involves: 129/Sv * 129S1/Sv * C57BL/6Bn * NAW) or (involves: 129S1/Sv * C57BL/6Bn * C57BL/6J * NAW)
Allelic Composition: MitfMi/MitfMi-J
Genetic Background: involves: C3HeB/Fe * C57BL/6J * C57BL/10J
Allelic Composition: Mitftm4Arnh/Mitfmi-vga9
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6N * CBA
Allelic Composition: Mitftm4Arnh/MitfMi
Genetic Background: involves: 129S6/SvEvTac * C57BL/6N
Allelic Composition: Mitftm5Arnh/MitfMi
Genetic Background: involves: 129S6/SvEvTac * C57BL/6N
Allelic Composition: Mitftm6Arnh/MitfMi
Genetic Background: involves: 129S6/SvEvTac * C57BL/6N
Allelic Composition: Mitftm7Arnh/MitfMi
Genetic Background: involves: 129S6/SvEvTac * C57BL/6N
Allelic Composition: Mitfmi-bw/Mitfmi-bw,Tg(Dct-LacZ)A12Jkn/0
Genetic Background: involves: C3H * C57BL/6 * C57BL/6J * CBA
|
| MP:0005172 | lack of eye pigmentation | "visual organs are devoid of coloring pigment in relation to control animals, usually resulting in a red or pink color" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:83500] |
Show
Allelic Composition: Lmnatm2Stw/Lmnatm2Stw
Genetic Background: involves: 129S1/Sv
Allelic Composition: MitfMi-wh/MitfMi-wh
Genetic Background: involves: C57BL * DBA
Allelic Composition: MitfMi-wh/Mitf+
Genetic Background: involves: C57BL * DBA
Allelic Composition: MitfMi/MitfMi
Genetic Background: Not Specified
Allelic Composition: MitfMi/Mitf+
Genetic Background: Not Specified
Allelic Composition: Mitfmi-di/Mitfmi-di
Genetic Background: (PT x C3H/HeH)F1
Allelic Composition: Mitfmi-ce/Mitfmi-ce
Genetic Background: DBA/2N
Allelic Composition: Mitfmi-enu122/Mitfmi-enu122
Genetic Background: involves: 102 * C3H
Allelic Composition: MitfMi-ws/MitfMi-ws
Genetic Background: involves: C57BL/6
Allelic Composition: MitfMi-wh/Mitf+,Myo5ad/Myo5ad
Genetic Background: involves: C57BL * DBA
Allelic Composition: MitfMi-Mee/?
Genetic Background: involves: C57BL/6 * CAST * FVB
Allelic Composition: MitfMi-Mee/MitfMi-Mee
Genetic Background: involves: C57BL/6 * FVB
Allelic Composition: MitfMi-Mee/Mitf+
Genetic Background: involves: C57BL/6 * FVB
Allelic Composition: MitfMi/Mitfmi-sp
Genetic Background: involves: C57BL/6J
Allelic Composition: MitfMi/Mitfmi-sp
Genetic Background: B6.Cg-MitfMi/Mitfmi-sp
Allelic Composition: MitfMi-Or/MitfMi-Or
Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: MitfMi-Or/Mitf+
Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: MitfMi-b/MitfMi-wh
Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: MitfMi-b/MitfMi-Or
Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Mitfmi-rw/Mitfmi-rw
Genetic Background: CBA/J
Allelic Composition: Mitfmi-x39/Mitf+
Genetic Background: involves: 102 * C3H
Allelic Composition: Mitfmi-enu198/Mitf+
Genetic Background: involves: 102 * C3H
Allelic Composition: MitfMi-wh/MitfMi-wh
Genetic Background: involves: C57BL * C57BL/6J * DBA
|
| MP:0005175 | non-pigmented tail tip | "lack of color at the end of the tail " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:83500] |
Show
Allelic Composition: Lmnatm2Stw/Lmnatm2Stw
Genetic Background: involves: 129S1/Sv
|
| MP:0005176 | eyelids fail to open | "eyes remain shut throughout life" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:83500] |
Show
Allelic Composition: Lmnatm2Stw/Lmnatm2Stw
Genetic Background: involves: 129S1/Sv
Allelic Composition: MitfMi/MitfMi
Genetic Background: Not Specified
Allelic Composition: MitfMi-Or/MitfMi-Or
Genetic Background: involves: 101/Rl * C3H/Rl
|
| MP:0005195 | abnormal posterior eye segment morphology | "anomalous structure of any of the parts of the eye that lie in back of, or dorsal to, the lens (but not inclusive) " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: MitfMi/MitfMi
Genetic Background: Not Specified
Allelic Composition: MitfMi-wh/MitfMi-wh
Genetic Background: B6.Cg-MitfMi-wh
|
| MP:0005201 | abnormal retinal pigment epithelium morphology | "anomaly in the epithelial layer of the retina composed of cells containing pigment granules " [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: MitfMi/MitfMi
Genetic Background: Not Specified
Allelic Composition: MitfMi-b/MitfMi-b
Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Mitfmi-vit/Mitfmi-vit
Genetic Background: C57BL/6J-Mitfmi-vit
Allelic Composition: MitfMi-wh/MitfMi-wh
Genetic Background: B6.Cg-MitfMi-wh
Allelic Composition: Mitfmi-vga9/Mitfmi-vga9
Genetic Background: involves: C57BL/6 * CBA
Allelic Composition: Mitfmi-vga9/Mitf+,Pax6Sey-Neu/Pax6+
Genetic Background: involves: C57BL/6 * CBA
Allelic Composition: Mitfmi-vga9/Mitfmi-vga9,Pax6Sey-Neu/Pax6Sey-Neu
Genetic Background: involves: C57BL/6 * CBA
Allelic Composition: Mitfmi-vga9/Mitfmi-vga9,Pax6Sey-Neu/Pax6+
Genetic Background: involves: C57BL/6 * CBA
Allelic Composition: Mitftm3.1Arnh/Mitftm3.1Arnh,Pax6Sey-Neu/Pax6+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6N
|
| MP:0005253 | abnormal eye physiology | "anomalous function and/or activity of the ocular system or any of its parts" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: MitfMi-b/MitfMi-b
Genetic Background: involves: 101/Rl * C3H/Rl
|
| MP:0005262 | coloboma | "anomaly in which some of the structures of the eye are absent due to incomplete fusion of the fetal intraocular fissure during gestation" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: MitfMi-H/MitfRorp
Genetic Background: involves: BALB/cAnN * C3H/HeN
Allelic Composition: MitfRorp/MitfRorp
Genetic Background: involves: BALB/cAnN * C3H/HeN
Allelic Composition: MitfMi/MitfMi
Genetic Background: Not Specified
|
| MP:0005322 | abnormal serotonin level | "anomalous concentration of biochemical messenger and regulator, found in the CNS, g.i. tract, and produced by platelets; it mediates neurotransmission, g.i. motility, hemostasis, and cardiovascular integrity " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Mitfmi-tg/Mitf+
Genetic Background: involves: C3H/HeNCrl * C57BL/6NCrl
Allelic Composition: Mitfmi-tg/Mitfmi-tg
Genetic Background: B6.Cg-Mitfmi-tg
|
| MP:0005358 | abnormal incisor morphology | "structural defect of the long pointed teeth; most anterior and prominent in the jaw" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:85574] |
Show
Allelic Composition: MitfMi-Or/MitfMi-Or
Genetic Background: involves: 101/Rl * C3H/Rl
|
| MP:0005362 | abnormal Langerhans cell physiology | "atypical or failure of normal function of the phagocytic dendritic cells principally found in the epidemis" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Mitfmi-vit/Mitfmi-vit
Genetic Background: C57BL/6J-Mitfmi-vit
|
| MP:0005366 | variegated coat color | "dappled coloration of the fur; mosaic" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
Show
Allelic Composition: MitfMi/Mitftm1Arnh
Genetic Background: involves: 129S1/Sv * C57BL/6
|
| MP:0005408 | hypopigmentation | "dilution of the pigment in the body" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Crybb2tm1Itl/Crybb2tm1Itl
Genetic Background: C57BL/6-Crybb2tm1Itl
Allelic Composition: MitfMi-wh/Mitfmi-sp
Genetic Background: B6.Cg-MitfMi-wh/Mitfmi-sp/J
Allelic Composition: MitfMi/Mitfmi-sp
Genetic Background: involves: C57BL/6J
|
| MP:0005409 | darkened coat color | "amount and distribution of yellow pigment (phaeomelanin) relative to black or brown pigment (eumelanin) is decreasesd when compared to wild-type agouti" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Mitftm5.1Arnh/MitfMi-wh
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL * C57BL/6N * DBA
Allelic Composition: Mitftm7.1Arnh/MitfMi-wh
Genetic Background: involves: 129S6/SvEvTac * C57BL * C57BL/6N * DBA
Allelic Composition: Mitftm6.1Arnh/MitfMi-wh
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL * C57BL/6N * DBA
|
| MP:0005422 | osteosclerosis | "abnormal hardening or eburnation (change in exposed subchondral bone in degenerative joint disease in which bone is converted into a dense substance with a smooth surface) of bone " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cml:Cathy M Lutz , Mouse Genome Informatics Curator] |
Show
Allelic Composition: MitfMi-Or/MitfMi-Or
Genetic Background: involves: 101/Rl * C3H/Rl
|
| MP:0005508 | abnormal skeleton morphology | "malformation of the bony framework of the body in vertebrates" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: MitfMi/MitfMi
Genetic Background: Not Specified
|
| MP:0005541 | abnormal iris stromal pigmentation | "anomalous coloring of the framework of the iris" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: MitfMi/Mitf+
Genetic Background: Not Specified
|
| MP:0005607 | decreased bleeding time | "less than the normal duration of blood flow after skin puncture; indicative of platement and capillary function" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission] |
Show
Allelic Composition: MitfMi-wh/MitfMi-wh
Genetic Background: B6.Cg-MitfMi-wh
|
| MP:0006010 | absent cochlear melanocytes | "absence of cochlear melanocytes (neural crest-derived intermediate cells of the stria vascularis) that are required for normal cochlear development." [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, smb:Susan M Bello, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Mitfmi-bw/Mitfmi-bw
Genetic Background: C3H
|
| MP:0006069 | abnormal retinal neuronal layer morphology | "malformation in any of the neuronal layers that make up the retina, including the ganglion cell, inner plexiform, inner nuclear, outer plexiform, outer nuclear layers, the inner and outer segments" [smb:Susan M Bello, Mouse Genome Informatics Curator, Gray s Anatomy:ISBN 0-914294-08-3] |
Show
Allelic Composition: MitfMi/MitfMi
Genetic Background: Not Specified
Allelic Composition: MitfMi-wh/MitfMi-wh
Genetic Background: B6.Cg-MitfMi-wh
|
| MP:0006089 | abnormal saccule morphology | "malformation in the smaller of the two sacs in the vestibule" [smb:Susan M Bello, Mouse Genome Informatics Curator, Taber s Cyclopedic Medical Dictionary:19th edition: ISBN N 0-8036-0655-99, J:92940] |
Show
Allelic Composition: MitfMi-wh/MitfMi-wh
Genetic Background: involves: C57BL * DBA
Allelic Composition: MitfMi/MitfMi
Genetic Background: Not Specified
Allelic Composition: MitfMi/Mitf+
Genetic Background: Not Specified
|
| MP:0006159 | ocular albinism | "absence of melanin production in the eye only" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator] |
Show
Allelic Composition: MitfMi-wh/MitfMi-wh
Genetic Background: involves: C57BL * DBA
|
| MP:0006226 | iris hypoplasia | "less than the normal number of cells in the iris" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Mitfmi-tg/Mitfmi-tg
Genetic Background: involves: C3H/HeNCrl * C57BL/6NCrl
|
| MP:0006243 | abnormal pupil dilation reaction to light | "the pupil fails to constrict fully when exposed to bright light" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator] |
Show
Allelic Composition: MitfMi-Mee/MitfMi-Mee
Genetic Background: involves: C57BL/6 * FVB
|
| MP:0006358 | absent pinna reflex | "complete failure to respond to an auditory stimulus by a characteristic ear twitch" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Mitfmi-enu5/Mitfmi-enu5
Genetic Background: involves: 102 * C3H/El
Allelic Composition: Mitfmi-enu5/Mitf+
Genetic Background: involves: 102 * C3H/El
|
| MP:0006395 | abnormal epiphyseal plate morphology | "any structural anomaly of the cartilaginous center of ossification on the bones permitting growth of the bone in both directions during development" [MESH:A02.835.232.251.352] |
Show
Allelic Composition: MitfMi-Or/MitfMi-Or
Genetic Background: involves: 101/Rl * C3H/Rl
|
| MP:0008447 | absent retinal cone cells | "absence of one of the photoreceptor cell types in the retina, in which the photopigment is in invaginations of the cell membrane of the outer segment" [MESH:A08.663.650.650.670.100] |
Show
Allelic Composition: Mitfmi-vit/Mitfmi-vit
Genetic Background: C57BL/6J-Mitfmi-vit
|
| MP:0008450 | retinal photoreceptor degeneration | "a retrogressive impairment of function or destruction of a cell specialized to detect and transduce light, including rods and cones of the retina" [MESH:A08.663.650.650, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Mitfmi-vit/Mitfmi-vit
Genetic Background: C57BL/6J-Mitfmi-vit
|
| MP:0008454 | absent retinal rod cells | "absence of one of the photoreceptor cell types of the vertebrate retina, in which the photopigment is in stacks of membranous disks separate from the outer cell membrane" [MESH:A08.663.650.650.670.650] |
Show
Allelic Composition: Mitfmi-vit/Mitfmi-vit
Genetic Background: C57BL/6J-Mitfmi-vit
|
| MP:0008480 | absent eye pigmentation | "absence of melanin (pigment) in the eye either due to absent melanocytes or failure of melanin synthesis" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Mitfmi-enu198/Mitfmi-enu198
Genetic Background: involves: 102 * C3H
Allelic Composition: MitfMi/MitfMi-J
Genetic Background: involves: C3HeB/Fe * C57BL/6J * C57BL/10J
|
| MP:0008585 | absent photoreceptor outer segment | "absence of the photoreceptor region that is rich in the visual pigment rhodopsin" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Mitfmi-di/Mitfmi-di
Genetic Background: (PT x C3H/HeH)F1
|
| MP:0008731 | abnormal hair shaft melanin granules | "any amount or distribution anomaly of pigment polymers in the hair shaft" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: MitfMi-wh/Mitfmi-sp
Genetic Background: B6.Cg-MitfMi-wh/Mitfmi-sp/J
|
| MP:0008770 | decreased survivor rate | "a smaller percentage of organisms than expected survive to adulthood and have a lifespan similar to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: MitfMi/MitfMi
Genetic Background: Not Specified
|
| MP:0009379 | abnormal foot pigmentation | "anomaly in the coloration of the foot" [MGI:mberry "Melissa Berry, Genetics Resources Curator"] |
Show
Allelic Composition: MitfMi-H/Mitf+
Genetic Background: involves: BALB/cAnN * C3H/HeN
Allelic Composition: MitfMi-wh/Mitf+
Genetic Background: involves: C57BL * DBA
Allelic Composition: Mitfmi-enu122/Mitfmi-enu122
Genetic Background: involves: 102 * C3H
Allelic Composition: MitfMi-wh/Mitfmi-sp
Genetic Background: B6.Cg-MitfMi-wh/Mitfmi-sp/J
|
| MP:0009772 | abnormal retinal development | "anomaly in any of the steps during embryogenesis that produce the nerve layer lining in the back of the eye which senses light, and creates impulses that travel through the optic nerve to the brain" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Mitfmi-di/Mitfmi-di
Genetic Background: (PT x C3H/HeH)F1
|
| MP:0009783 | abnormal melanoblast morphology | "any structural anomaly of a cell that originates from the neural crest and differentiates into a pigment cell" [CL:0000541] |
Show
Allelic Composition: Mitfmi-bw/Mitfmi-bw,Tg(Dct-LacZ)A12Jkn/0
Genetic Background: involves: C3H * C57BL/6 * C57BL/6J * CBA
|
| MP:0009784 | abnormal melanoblast migration | "defect in the dispersion of the cells that originate from the neural crest and differentiate into pigment cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Mitfmi-bw/Mitfmi-bw,Tg(Dct-LacZ)A12Jkn/0
Genetic Background: involves: C3H * C57BL/6 * C57BL/6J * CBA
|
| MP:0009877 | exostosis | "a projection of bone, sometimes a benign tumor, that is capped by cartilage and arises from a bone that develops from cartilage" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Mitfmi-ew/Mitfmi-ew
Genetic Background: involves: C57BL/6Bn * NAW
|
| MP:0010016 | variable depigmentation | "absence or loss of normal pigment in the skin in various and irregular patterns" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Mitfmi-vit/Mitfmi-vit
Genetic Background: C57BL/6J-Mitfmi-vit
|
| MP:0010932 | increased trabecular bone connectivity density | "increase in the extent of attachments between trabeculae; it may be expressed in ratios of nodes to free ends, trabecular bone pattern factor, and related measures" [ISBN:0120986523 "Principles of bone biology, Volume 1, Bilezikian, JP et al, eds"] |
Show
Allelic Composition: MitfMi-Or/MitfMi-Or
Genetic Background: involves: 101/Rl * C3H/Rl
|
| MP:0011085 | complete postnatal lethality | "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
Show
Allelic Composition: Mitfmi-vga9/Mitfmi-vga9,Tfe3tm1Est/Tfe3tm1Est
Genetic Background: either: (involves: 129/Sv * 129S1/Sv * C57BL/6 * CBA) or (involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA)
Allelic Composition: Mitfmi-ew/Mitfmi-ew,Tfe3tm1Est/Tfe3tm1Est
Genetic Background: either: (involves: 129/Sv * 129S1/Sv * C57BL/6Bn * NAW) or (involves: 129S1/Sv * C57BL/6Bn * C57BL/6J * NAW)
|
| MP:0011086 | partial postnatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
Show
Allelic Composition: MitfMi-wh/MitfMi-wh,Tfe3tm1Est/Tfe3tm1Est
Genetic Background: either: (involves: 129/Sv * 129S1/Sv * C57BL * DBA) or (involves: 129S1/Sv * C57BL * C57BL/6J * DBA)
|
| MP:0011277 | decreased tail pigmentation | "visually detectable dilution of pigment present on the tail surface" [MGI:csmith] |
Show
Allelic Composition: MitfMi-H/Mitf+
Genetic Background: involves: BALB/cAnN * C3H/HeN
Allelic Composition: MitfRorp/Mitf+
Genetic Background: involves: BALB/cAnN * C3H/HeN
Allelic Composition: MitfMi-wh/Mitf+
Genetic Background: involves: C57BL * DBA
Allelic Composition: MitfMi-b/Mitf+
Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: Mitfmi-enu122/Mitfmi-enu122
Genetic Background: involves: 102 * C3H
Allelic Composition: MitfMi-wh/Mitfmi-sp
Genetic Background: B6.Cg-MitfMi-wh/Mitfmi-sp/J
Allelic Composition: MitfMi-Or/Mitf+
Genetic Background: involves: 101/Rl * C3H/Rl
|
| MP:0011279 | decreased ear pigmentation | "visually detectable dilution of pigment present in the outer ear" [MGI:csmith] |
Show
Allelic Composition: MitfMi-H/Mitf+
Genetic Background: involves: BALB/cAnN * C3H/HeN
Allelic Composition: MitfRorp/Mitf+
Genetic Background: involves: BALB/cAnN * C3H/HeN
Allelic Composition: MitfMi-b/Mitf+
Genetic Background: involves: 101/Rl * C3H/Rl
Allelic Composition: MitfMi-wh/Mitfmi-sp
Genetic Background: B6.Cg-MitfMi-wh/Mitfmi-sp/J
Allelic Composition: MitfMi-Or/Mitf+
Genetic Background: involves: 101/Rl * C3H/Rl
|
| MP:0011697 | vacuolated lens | "fluid filled cavities are present in the cytoplasm of the transparent structure of the eye responsible for focusing light" [MGI:llw2] |
Show
Allelic Composition: MitfMi-Mee/MitfMi-Mee
Genetic Background: involves: C57BL/6 * FVB
|
| MP:0011967 | increased or absent threshold for auditory brainstem response | "increase in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system, or complete lack of a recordable response at any frequency or broadband click" [MGI:csmith] |
Show
Allelic Composition: Mitfmi-bw/Mitfmi-bw
Genetic Background: C3H
|
| MP:0012023 | decreased melanocyte number | "reduced number of the cells that produce pigment" [MGI:llw2] |
Show
Allelic Composition: Mitfmi-bw/Mitfmi-bw,Tg(Dct-LacZ)A12Jkn/0
Genetic Background: involves: C3H * C57BL/6 * C57BL/6J * CBA
|
| MP:0012535 | abnormal optic fissure closure | "failure to initiate and/or complete closure of the transient gap in the ventral margin of the developing optic cup; fusion of the optic fissure begins with apposition of the inferior lips of the ventral-most optic cup and continues anteriorly toward its rim and posteriorly along the optic stalk; failure or late closure of the optic fissure prevents the establishment of normal fetal intraocular pressure and can result in microphthalmia associataed with colobomas" [MGI:anna] |
Show
Allelic Composition: MitfMi-wh/MitfMi-wh
Genetic Background: B6.Cg-MitfMi-wh
|
| MP:0013743 | ciliary body hypoplasia | "underdevelopment or reduced size, usually due to a reduced number of cells, of the thickened portion of the vascular tunic which lies between the choroid and the iris" [ISBN:0-683-40008-8, MGI:Anna] |
Show
Allelic Composition: Mitfmi-tg/Mitfmi-tg
Genetic Background: involves: C3H/HeNCrl * C57BL/6NCrl
|
| MP:0014164 | abnormal ciliary process morphology | " any structural anomaly of any of the pigmented processes that radiate from the ciliary muscle and give attachments to ligaments supporting the lens of the eye; these processes increase in thickness as they advance from the orbiculus ciliaris to the external border of the iris, and together with the folds (plicae) in the furrows between them, constitute the corona ciliaris; ciliary processes produce aqueous humor" [http://www.medilexicon.com/medicaldictionary.php?s=processus+ciliaris] |
Show
Allelic Composition: MitfMi-b/MitfMi-b
Genetic Background: involves: 101/Rl * C3H/Rl
|
