ENSMUSG00000035696


Mus musculus

Features
Gene ID: ENSMUSG00000035696
  
Biological name :Rnf38
  
Synonyms : Mus musculus ring finger protein 38 (Rnf38), transcript variant 3, mRNA. / Q8BI21 / Rnf38
  
Possible biological names infered from orthology : Q9H0F5 / ring finger protein 38
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: B1
Gene start: 44126210
Gene end: 44233789
  
Corresponding Affymetrix probe sets: 10512655 (MoGene1.0st)   1428101_at (Mouse Genome 430 2.0 Array)   1431993_a_at (Mouse Genome 430 2.0 Array)   1442259_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000116642
Ensembl peptide - ENSMUSP00000103467
Ensembl peptide - ENSMUSP00000119889
Ensembl peptide - ENSMUSP00000122342
Ensembl peptide - ENSMUSP00000121329
Ensembl peptide - ENSMUSP00000038477
Ensembl peptide - ENSMUSP00000095702
Ensembl peptide - ENSMUSP00000099998
NCBI entrez gene - 73469     See in Manteia.
MGI - MGI:1920719
RefSeq - XM_011250120
RefSeq - XM_006538303
RefSeq - XM_006538304
RefSeq - XM_006538305
RefSeq - XM_006538306
RefSeq - XM_011250115
RefSeq - XM_011250116
RefSeq - XM_011250117
RefSeq - XM_011250118
RefSeq - XM_011250119
RefSeq - NM_001038993
RefSeq - NM_001355181
RefSeq - NM_175201
RefSeq - XM_006538298
RefSeq - XM_006538299
RefSeq - XM_006538300
RefSeq - XM_006538301
RefSeq - XM_006538302
RefSeq Peptide - NP_001034082
RefSeq Peptide - NP_001342110
RefSeq Peptide - NP_780410
swissprot - Q3UH35
swissprot - E9Q959
swissprot - B1AWE7
swissprot - Q8BI21
swissprot - B1AWE9
swissprot - B1AWE8
Ensembl - ENSMUSG00000035696
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rnf38ENSDARG00000062055Danio rerio
 RNF38ENSGALG00000015311Gallus gallus
 RNF38ENSG00000137075Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rnf44 / Q3UHJ8 / RING finger protein 44 / Q7L0R7*ENSMUSG0000003492856
Rlim / Q9WTV7 / Mus musculus ring finger protein, LIM domain interacting (Rlim), transcript variant 2, mRNA. / Q9NVW2* / ring finger protein, LIM domain interacting*ENSMUSG0000005653719
Rnf6 / Q9DBU5 / E3 ubiquitin-protein ligase RNF6 / Q9Y252* / ring finger protein 6*ENSMUSG0000002963419


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008584 male gonad development IEA
 biological_processGO:0016567 protein ubiquitination ISO
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IBA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0036126 sperm flagellum IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0010097 abnormal retinal blood vessel morphology "any structural anomaly of the blood vessels supplying the retina" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Rnf10tm1b(KOMP)Wtsi/Rnf10tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Rnf10tm1b(KOMP)Wtsi/Ucd

 MP:0010123 increased bone mineral content "elevation in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Rnf10tm1b(KOMP)Wtsi/Rnf10tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Rnf10tm1b(KOMP)Wtsi/Ucd

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Rnf10tm1b(KOMP)Wtsi/Rnf10tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Rnf10tm1b(KOMP)Wtsi/Ucd

 MP:0011967 increased or absent threshold for auditory brainstem response "increase in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system, or complete lack of a recordable response at any frequency or broadband click" [MGI:csmith]
Show

Allelic Composition: Rnf10tm1b(KOMP)Wtsi/Rnf10tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Rnf10tm1b(KOMP)Wtsi/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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