ENSMUSG00000036402


Mus musculus

Features
Gene ID: ENSMUSG00000036402
  
Biological name :Gng12
  
Synonyms : Gng12 / guanine nucleotide binding protein (G protein), gamma 12 / Q9DAS9
  
Possible biological names infered from orthology : G protein subunit gamma 12 / Q9UBI6
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: C1
Gene start: 66896397
Gene end: 67021350
  
Corresponding Affymetrix probe sets: 10538842 (MoGene1.0st)   1421947_at (Mouse Genome 430 2.0 Array)   1455089_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000145234
Ensembl peptide - ENSMUSP00000109866
Ensembl peptide - ENSMUSP00000145346
Ensembl peptide - ENSMUSP00000046557
Ensembl peptide - ENSMUSP00000109860
Ensembl peptide - ENSMUSP00000109862
Ensembl peptide - ENSMUSP00000109863
Ensembl peptide - ENSMUSP00000109864
Ensembl peptide - ENSMUSP00000109865
NCBI entrez gene - 14701     See in Manteia.
MGI - MGI:1336171
RefSeq - XM_006505542
RefSeq - NM_001177556
RefSeq - NM_001177557
RefSeq - NM_001177558
RefSeq - NM_001177559
RefSeq - NM_001177560
RefSeq - NM_025278
RefSeq Peptide - NP_001171031
RefSeq Peptide - NP_079554
RefSeq Peptide - NP_001171028
RefSeq Peptide - NP_001171027
RefSeq Peptide - NP_001171029
RefSeq Peptide - NP_001171030
swissprot - Q9DAS9
swissprot - A0A0N4SW28
swissprot - A0A0N4SVT3
Ensembl - ENSMUSG00000036402
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gng12aENSDARG00000003375Danio rerio
 si:dkey-44g17.6ENSDARG00000098123Danio rerio
 GNG12ENSGALG00000026591Gallus gallus
 GNG12ENSG00000172380Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gng7 / Q61016 / guanine nucleotide binding protein (G protein), gamma 7 / O60262* / G protein subunit gamma 7*ENSMUSG0000004824072
Gm5741 / G protein subunit gamma 14 / GNG14* / A0A1W2PPG7*ENSMUSG0000009584563
Gng2 / P63213 / guanine nucleotide binding protein (G protein), gamma 2 / P59768* / G protein subunit gamma 2*ENSMUSG0000004300461
Gng3 / P63216 / guanine nucleotide binding protein (G protein), gamma 3 / P63215* / G protein subunit gamma 3*ENSMUSG0000007165860
Gng4 / P50153 / guanine nucleotide binding protein (G protein), gamma 4 / P50150* / G protein subunit gamma 4*ENSMUSG0000002130354
Gng5 / Q80SZ7 / guanine nucleotide binding protein (G protein), gamma 5 / P63218* / G protein subunit gamma 5*ENSMUSG0000006852347
Gng8 / P63078 / guanine nucleotide binding protein (G protein), gamma 8 / Q9UK08* / G protein subunit gamma 8*ENSMUSG0000006359447
Gng10 / Q9CXP8 / guanine nucleotide binding protein (G protein), gamma 10 / P50151* / G protein subunit gamma 10*ENSMUSG0000003860746


Protein motifs (from Interpro)
Interpro ID Name
 IPR001770  G-protein, gamma subunit
 IPR015898  G-protein gamma-like domain
 IPR036284  G-protein gamma-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0021987 cerebral cortex development IEA
 biological_processGO:0032496 response to lipopolysaccharide IEA
 cellular_componentGO:0005834 heterotrimeric G-protein complex IEA
 cellular_componentGO:0005884 actin filament IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0030165 PDZ domain binding ISO
 molecular_functionGO:0042301 phosphate ion binding IEA


Pathways (from Reactome)
Pathway description
Activation of G protein gated Potassium channels
Glucagon signaling in metabolic regulation
G-protein activation
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
ADP signalling through P2Y purinoceptor 12
G beta:gamma signalling through PI3Kgamma
Prostacyclin signalling through prostacyclin receptor
Adrenaline,noradrenaline inhibits insulin secretion
Ca2+ pathway
G alpha (q) signalling events
G alpha (12/13) signalling events
G beta:gamma signalling through PLC beta
G alpha (s) signalling events
ADP signalling through P2Y purinoceptor 1
G alpha (i) signalling events
G alpha (z) signalling events
Glucagon-type ligand receptors
Thromboxane signalling through TP receptor
Vasopressin regulates renal water homeostasis via Aquaporins
Thrombin signalling through proteinase activated receptors (PARs)
Presynaptic function of Kainate receptors
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr