Manteia

ENSMUSG00000037542

Mus musculus

Features

Gene ID:	ENSMUSG00000037542

Biological name :	Aldh8a1

Synonyms :	Aldehyde dehydrogenase family 8 member A1 / Aldh8a1 / Q8BH00

Possible biological names infered from orthology :	aldehyde dehydrogenase 8 family member A1 / Q9H2A2

Species:	Mus musculus

Chr. number:	10
Strand:	1
Band:	A3
Gene start:	21377291
Gene end:	21396585

Corresponding Affymetrix probe sets:	10362052 (MoGene1.0st) 1427336_at (Mouse Genome 430 2.0 Array) 1427337_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000038878 NCBI entrez gene - 237320 See in Manteia. MGI - MGI:2653900 RefSeq - NM_178713 RefSeq Peptide - NP_848828 swissprot - Q8BH00 Ensembl - ENSMUSG00000037542

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Q8R0Y6 / Aldh1l1 / Mus musculus aldehyde dehydrogenase 1 family, member L1 (Aldh1l1), transcript variant 2, mRNA. / O75891* / aldehyde dehydrogenase 1 family member L1*	ENSMUSG00000030088	38
Q9CZS1 / Aldh1b1 / Aldehyde dehydrogenase X, mitochondrial / P30837* / aldehyde dehydrogenase 1 family member B1*	ENSMUSG00000035561	38
O35945 / Aldh1a7 / Aldehyde dehydrogenase, cytosolic 1 / P00352* / ALDH1A1* / aldehyde dehydrogenase 1 family member A1*	ENSMUSG00000024747	38
Q62148 / Aldh1a2 / Retinal dehydrogenase 2 / O94788* / aldehyde dehydrogenase 1 family member A2*	ENSMUSG00000013584	37
Aldh2 / P47738 / Aldehyde dehydrogenase, mitochondrial / P05091* / AC002996.1* / aldehyde dehydrogenase 2 family (mitochondrial)*	ENSMUSG00000029455	37
Q9JHW9 / Aldh1a3 / Aldehyde dehydrogenase family 1 member A3 / P47895* / aldehyde dehydrogenase 1 family member A3*	ENSMUSG00000015134	37
Aldh9a1 / aldehyde dehydrogenase 9 family member A1 / P49189*	ENSMUSG00000026687	37
P24549 / Aldh1a1 / Retinal dehydrogenase 1 / P00352* / aldehyde dehydrogenase 1 family member A1*	ENSMUSG00000053279	37
Q8K009 / Aldh1l2 / Mitochondrial 10-formyltetrahydrofolate dehydrogenase / Q3SY69* / aldehyde dehydrogenase 1 family member L2*	ENSMUSG00000020256	36
Q9DBF1 / Aldh7a1 / Alpha-aminoadipic semialdehyde dehydrogenase / P49419* / aldehyde dehydrogenase 7 family member A1*	ENSMUSG00000053644	25

Protein motifs (from Interpro)

Interpro ID	Name
IPR015590	Aldehyde dehydrogenase domain
IPR016160	Aldehyde dehydrogenase, cysteine active site
IPR016161	Aldehyde/histidinol dehydrogenase
IPR016162	Aldehyde dehydrogenase, N-terminal
IPR029510	Aldehyde dehydrogenase, glutamic acid active site

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0008152	metabolic process	IEA
biological_process	GO:0042573	retinoic acid metabolic process	IEA
biological_process	GO:0042574	retinal metabolic process	IEA
biological_process	GO:0042904	9-cis-retinoic acid biosynthetic process	IDA
biological_process	GO:0055114	oxidation-reduction process	IEA
cellular_component	GO:0005622	intracellular	IEA
cellular_component	GO:0005737	cytoplasm	IEA
molecular_function	GO:0001758	retinal dehydrogenase activity	IEA
molecular_function	GO:0016491	oxidoreductase activity	IEA
molecular_function	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	IEA

Pathways (from Reactome)

Pathway description

RA biosynthesis pathway

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr