ENSMUSG00000053644


Mus musculus

Features
Gene ID: ENSMUSG00000053644
  
Biological name :Aldh7a1
  
Synonyms : Aldh7a1 / Alpha-aminoadipic semialdehyde dehydrogenase / Q9DBF1
  
Possible biological names infered from orthology : aldehyde dehydrogenase 7 family member A1 / P49419
  
Species: Mus musculus
  
Chr. number: 18
Strand: -1
Band: D3
Gene start: 56509687
Gene end: 56572951
  
Corresponding Affymetrix probe sets: 10458960 (MoGene1.0st)   1415902_at (Mouse Genome 430 2.0 Array)   1448137_at (Mouse Genome 430 2.0 Array)   1460167_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000133372
Ensembl peptide - ENSMUSP00000134192
Ensembl peptide - ENSMUSP00000133970
Ensembl peptide - ENSMUSP00000065089
Ensembl peptide - ENSMUSP00000127625
Ensembl peptide - ENSMUSP00000127652
NCBI entrez gene - 110695     See in Manteia.
MGI - MGI:108186
RefSeq - NM_001127338
RefSeq - NM_138600
RefSeq Peptide - NP_001120810
RefSeq Peptide - NP_613066
swissprot - Q9DBF1
swissprot - E9Q1G1
swissprot - G3UY72
swissprot - G3UYR8
swissprot - E9Q1H3
Ensembl - ENSMUSG00000053644
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aldh7a1ENSDARG00000018426Danio rerio
 ALDH7A1ENSGALG00000008229Gallus gallus
 P49419ENSG00000164904Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8K009 / Aldh1l2 / Mitochondrial 10-formyltetrahydrofolate dehydrogenase / Q3SY69* / aldehyde dehydrogenase 1 family member L2*ENSMUSG0000002025629
Q9CZS1 / Aldh1b1 / Aldehyde dehydrogenase X, mitochondrial / P30837* / aldehyde dehydrogenase 1 family member B1*ENSMUSG0000003556126
Aldh2 / P47738 / Aldehyde dehydrogenase, mitochondrial / P05091* / AC002996.1* / aldehyde dehydrogenase 2 family (mitochondrial)*ENSMUSG0000002945526
Q62148 / Aldh1a2 / Retinal dehydrogenase 2 / O94788* / aldehyde dehydrogenase 1 family member A2*ENSMUSG0000001358426
Q9JHW9 / Aldh1a3 / Aldehyde dehydrogenase family 1 member A3 / P47895* / aldehyde dehydrogenase 1 family member A3*ENSMUSG0000001513426
P24549 / Aldh1a1 / Retinal dehydrogenase 1 / P00352* / aldehyde dehydrogenase 1 family member A1*ENSMUSG0000005327926
Q8R0Y6 / Aldh1l1 / Mus musculus aldehyde dehydrogenase 1 family, member L1 (Aldh1l1), transcript variant 2, mRNA. / O75891* / aldehyde dehydrogenase 1 family member L1*ENSMUSG0000003008826
O35945 / Aldh1a7 / Aldehyde dehydrogenase, cytosolic 1 / P00352* / ALDH1A1* / aldehyde dehydrogenase 1 family member A1*ENSMUSG0000002474725
Aldh9a1 / aldehyde dehydrogenase 9 family member A1 / P49189*ENSMUSG0000002668723
Q8BH00 / Aldh8a1 / Aldehyde dehydrogenase family 8 member A1 / Q9H2A2* / aldehyde dehydrogenase 8 family member A1*ENSMUSG0000003754222


Protein motifs (from Interpro)
Interpro ID Name
 IPR015590  Aldehyde dehydrogenase domain
 IPR016161  Aldehyde/histidinol dehydrogenase
 IPR016162  Aldehyde dehydrogenase, N-terminal
 IPR029510  Aldehyde dehydrogenase, glutamic acid active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0019285 glycine betaine biosynthetic process from choline IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0004029 aldehyde dehydrogenase (NAD) activity IEA
 molecular_functionGO:0004043 L-aminoadipate-semialdehyde dehydrogenase activity ISO
 molecular_functionGO:0008802 betaine-aldehyde dehydrogenase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA


Pathways (from Reactome)
Pathway description
Choline catabolism
Lysine catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Baxtm1Dlo/Baxtm1Dlo
Genetic Background: involves: 129P2/OlaHsd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000053644 Q9DBF1 / Aldh7a1 / Alpha-aminoadipic semialdehyde dehydrogenase / P49419* / aldehyde dehydrogenase 7 family member A1*  / complex






 

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contact: otassy@igbmc.fr