ENSMUSG00000038279


Mus musculus

Features
Gene ID: ENSMUSG00000038279
  
Biological name :Nop2
  
Synonyms : Nop2 / NOP2 nucleolar protein
  
Possible biological names infered from orthology : P46087
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: F2
Gene start: 125131909
Gene end: 125144753
  
Corresponding Affymetrix probe sets: 10541845 (MoGene1.0st)   1424019_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000047123
Ensembl peptide - ENSMUSP00000145333
NCBI entrez gene - 110109     See in Manteia.
MGI - MGI:107891
RefSeq - NM_138747
RefSeq - XM_017321322
RefSeq - XM_017321323
RefSeq Peptide - NP_620086
swissprot - E9QN31
swissprot - A0A0N4SW16
Ensembl - ENSMUSG00000038279
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nop2ENSDARG00000043304Danio rerio
 NOP2ENSGALG00000037807Gallus gallus
 NOP2ENSG00000111641Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nsun6 / Q7TS68 / Putative methyltransferase NSUN6 / Q8TEA1* / NOP2/Sun RNA methyltransferase family member 6*ENSMUSG0000002670713
Nsun4 / Q9CZ57 / C4P6S0 / 5-methylcytosine rRNA methyltransferase NSUN4 / Q96CB9* / NOP2/Sun RNA methyltransferase family member 4*ENSMUSG0000002870611
Nsun3 / Q8CCT7 / tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial / Q9H649* / NOP2/Sun RNA methyltransferase family member 3*ENSMUSG0000005031211


Protein motifs (from Interpro)
Interpro ID Name
 IPR001678  SAM-dependent methyltransferase RsmB/NOP2-type
 IPR011023  Nop2p
 IPR012586  P120R repeat
 IPR018314  Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site
 IPR023267  RNA (C5-cytosine) methyltransferase
 IPR023273  RNA (C5-cytosine) methyltransferase, NOP2
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase
 IPR031341  Ribosomal RNA small subunit methyltransferase F, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000027 ribosomal large subunit assembly IEA
 biological_processGO:0006364 rRNA processing IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0032259 methylation IEA
 biological_processGO:1901796 regulation of signal transduction by p53 class mediator IEA
 cellular_componentGO:0005730 nucleolus IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008757 S-adenosylmethionine-dependent methyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011091 complete prenatal lethality "death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
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Allelic Composition: Glultm1.1Geno/Glultm1.1Geno,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: C57BL/6 * C57BL/6J * DBA

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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