ENSMUSG00000038965


Mus musculus

Features
Gene ID: ENSMUSG00000038965
  
Biological name :Ube2l3
  
Synonyms : P68037 / Ube2l3 / ubiquitin-conjugating enzyme E2L 3
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 16
Strand: -1
Band: A3
Gene start: 17152015
Gene end: 17201492
  
Corresponding Affymetrix probe sets: 10362310 (MoGene1.0st)   10438109 (MoGene1.0st)   10458841 (MoGene1.0st)   10499187 (MoGene1.0st)   10502898 (MoGene1.0st)   1417907_at (Mouse Genome 430 2.0 Array)   1417908_s_at (Mouse Genome 430 2.0 Array)   1448879_at (Mouse Genome 430 2.0 Array)   1448880_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000087658
NCBI entrez gene - 22195     See in Manteia.
MGI - MGI:109240
RefSeq - XM_006522004
RefSeq - NM_009456
RefSeq Peptide - NP_033482
swissprot - P68037
swissprot - Q561N4
Ensembl - ENSMUSG00000038965
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ube2l3aENSDARG00000112087Danio rerio
 ube2l3bENSDARG00000027141Danio rerio
 UBE2L3ENSGALG00000036739Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9QZU9 / Ube2l6 / ubiquitin-conjugating enzyme E2L 6 / O14933*ENSMUSG0000002707850
P62838 / Ube2d2a / ubiquitin-conjugating enzyme E2D 2A / UBE2D2* / P62837* / ubiquitin conjugating enzyme E2 D2*ENSMUSG0000009189638
Q6ZWY6 / Ube2d2b / ubiquitin-conjugating enzyme E2D 2BENSMUSG0000006344738
P61080 / Ube2d1 / ubiquitin-conjugating enzyme E2D 1 / P51668*ENSMUSG0000001992738
Ube2dnl2 / ubiquitin-conjugating enzyme E2D N-terminal like 2ENSMUSG0000004707937
Ube2dnl1ENSMUSG0000005043536
P61079 / Ube2d3 / ubiquitin-conjugating enzyme E2D 3 / P61077*ENSMUSG0000007857835
P52483 / Ube2e3 / ubiquitin-conjugating enzyme E2E 3 / Q969T4*ENSMUSG0000002701134
P52482 / Ube2e1 / ubiquitin-conjugating enzyme E2E 1 / P51965*ENSMUSG0000002177434
Q91W82 / Ube2e2 / ubiquitin-conjugating enzyme E2E 2 / Q96LR5*ENSMUSG0000005831734
Ube2s / Q921J4 / ubiquitin-conjugating enzyme E2S / Q16763*ENSMUSG0000006086026


Protein motifs (from Interpro)
Interpro ID Name
 IPR000608  Ubiquitin-conjugating enzyme E2
 IPR016135  Ubiquitin-conjugating enzyme/RWD-like
 IPR023313  Ubiquitin-conjugating enzyme, active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination ISS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated ISO
 biological_processGO:0008283 cell proliferation ISS
 biological_processGO:0016567 protein ubiquitination ISO
 biological_processGO:0031398 positive regulation of protein ubiquitination ISO
 biological_processGO:0044770 cell cycle phase transition ISO
 biological_processGO:0051443 positive regulation of ubiquitin-protein transferase activity ISO
 biological_processGO:0070979 protein K11-linked ubiquitination ISO
 biological_processGO:0071383 cellular response to steroid hormone stimulus ISS
 biological_processGO:0071385 cellular response to glucocorticoid stimulus ISS
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm ISS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003713 transcription coactivator activity ISO
 molecular_functionGO:0004842 ubiquitin-protein transferase activity ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding ISO
 molecular_functionGO:0061631 ubiquitin conjugating enzyme activity ISO
 molecular_functionGO:0097027 ubiquitin-protein transferase activator activity ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001711 abnormal placenta 
Show

Allelic Composition: Vhltm1Wml/Vhltm1Wml
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0001712 abnormal placental development "malformed or incomplete differentiation of the organ of metabolic exchange between the fetus and mother" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61790]
Show

Allelic Composition: Vhltm1Wml/Vhltm1Wml
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Vhltm1Wml/Vhltm1Wml
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0008803 abnormal placental labyrinth vasculature morphology "any structural anomaly in blood vessels of the layer of the placenta where embryonic and maternal blood vessels interdigitate" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Vhltm1Wml/Vhltm1Wml
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0011089 complete perinatal lethality "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
Show

Allelic Composition: Vhltm1Wml/Vhltm1Wml
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0011109 partial lethality throughout fetal growth and development "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith]
Show

Allelic Composition: Vhltm1Wml/Vhltm1Wml
Genetic Background: involves: 129S4/SvJae * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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