ENSMUSG00000060860


Mus musculus

Features
Gene ID: ENSMUSG00000060860
  
Biological name :Ube2s
  
Synonyms : Q921J4 / Ube2s / ubiquitin-conjugating enzyme E2S
  
Possible biological names infered from orthology : Q16763
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: A1
Gene start: 4794546
Gene end: 4812590
  
Corresponding Affymetrix probe sets: 10559676 (MoGene1.0st)   10585586 (MoGene1.0st)   1416726_s_at (Mouse Genome 430 2.0 Array)   1430962_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000078459
Ensembl peptide - ENSMUSP00000146276
Ensembl peptide - ENSMUSP00000146232
Ensembl peptide - ENSMUSP00000146213
NCBI entrez gene - 77891     See in Manteia.
MGI - MGI:1925141
RefSeq - NM_133777
RefSeq Peptide - NP_598538
swissprot - A0A0U1RQ37
swissprot - A0A0U1RQ22
swissprot - A0A0U1RQ75
swissprot - Q921J4
Ensembl - ENSMUSG00000060860
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ube2sENSDARG00000031775Danio rerio
 UBE2SENSG00000108106Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P62838 / Ube2d2a / ubiquitin-conjugating enzyme E2D 2A / UBE2D2* / P62837* / ubiquitin conjugating enzyme E2 D2*ENSMUSG0000009189625
Q6ZWY6 / Ube2d2b / ubiquitin-conjugating enzyme E2D 2BENSMUSG0000006344725
P61080 / Ube2d1 / ubiquitin-conjugating enzyme E2D 1 / P51668*ENSMUSG0000001992725
Ube2dnl1ENSMUSG0000005043524
Ube2dnl2 / ubiquitin-conjugating enzyme E2D N-terminal like 2ENSMUSG0000004707924
P52483 / Ube2e3 / ubiquitin-conjugating enzyme E2E 3 / Q969T4*ENSMUSG0000002701123
P61079 / Ube2d3 / ubiquitin-conjugating enzyme E2D 3 / P61077*ENSMUSG0000007857823
P52482 / Ube2e1 / ubiquitin-conjugating enzyme E2E 1 / P51965*ENSMUSG0000002177423
Q91W82 / Ube2e2 / ubiquitin-conjugating enzyme E2E 2 / Q96LR5*ENSMUSG0000005831722
P68037 / Ube2l3 / ubiquitin-conjugating enzyme E2L 3ENSMUSG0000003896518
Q9QZU9 / Ube2l6 / ubiquitin-conjugating enzyme E2L 6 / O14933*ENSMUSG0000002707816


Protein motifs (from Interpro)
Interpro ID Name
 IPR000608  Ubiquitin-conjugating enzyme E2
 IPR016135  Ubiquitin-conjugating enzyme/RWD-like
 IPR023313  Ubiquitin-conjugating enzyme, active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IBA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IBA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0010458 exit from mitosis IEA
 biological_processGO:0010994 free ubiquitin chain polymerization IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0031145 anaphase-promoting complex-dependent catabolic process IEA
 biological_processGO:0035519 protein K29-linked ubiquitination IEA
 biological_processGO:0044314 protein K27-linked ubiquitination IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0070534 protein K63-linked ubiquitination IEA
 biological_processGO:0070979 protein K11-linked ubiquitination IEA
 biological_processGO:0085020 protein K6-linked ubiquitination IEA
 biological_processGO:1904668 positive regulation of ubiquitin protein ligase activity IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005680 anaphase-promoting complex IEA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IBA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA
 molecular_functionGO:0061631 ubiquitin conjugating enzyme activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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