ENSG00000108106


Homo sapiens

Features
Gene ID: ENSG00000108106
  
Biological name :UBE2S
  
Synonyms : Q16763 / UBE2S / ubiquitin conjugating enzyme E2 S
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.42
Gene start: 55399745
Gene end: 55407777
  
Corresponding Affymetrix probe sets: 202779_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000264552
Ensembl peptide - ENSP00000466388
Ensembl peptide - ENSP00000467409
NCBI entrez gene - 27338     See in Manteia.
OMIM - 610309
RefSeq - XM_011526752
RefSeq - NM_014501
RefSeq Peptide - NP_055316
swissprot - K7EM75
swissprot - Q16763
swissprot - K7EPJ1
Ensembl - ENSG00000108106
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ube2sENSDARG00000031775Danio rerio
 Ube2sENSMUSG00000060860Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9Y2X8 / UBE2D4 / ubiquitin conjugating enzyme E2 D4 (putative)ENSG0000007896726
P51668 / UBE2D1 / ubiquitin conjugating enzyme E2 D1ENSG0000007240125
P62837 / UBE2D2 / ubiquitin conjugating enzyme E2 D2ENSG0000013150825
P61077 / UBE2D3 / ubiquitin conjugating enzyme E2 D3ENSG0000010933224
P51965 / UBE2E1 / ubiquitin conjugating enzyme E2 E1ENSG0000017014223
Q96LR5 / UBE2E2 / ubiquitin conjugating enzyme E2 E2ENSG0000018224723
Q969T4 / UBE2E3 / ubiquitin conjugating enzyme E2 E3ENSG0000017003523
UBE2L5 / ubiquitin conjugating enzyme E2 L5ENSG0000023644418
P68036 / UBE2L3 / ubiquitin conjugating enzyme E2 L3ENSG0000018565118
O14933 / UBE2L6 / ubiquitin conjugating enzyme E2 L6ENSG0000015658717


Protein motifs (from Interpro)
Interpro ID Name
 IPR000608  Ubiquitin-conjugating enzyme E2
 IPR016135  Ubiquitin-conjugating enzyme/RWD-like
 IPR023313  Ubiquitin-conjugating enzyme, active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006464 cellular protein modification process TAS
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0010458 exit from mitosis IMP
 biological_processGO:0010994 free ubiquitin chain polymerization IDA
 biological_processGO:0016567 protein ubiquitination TAS
 biological_processGO:0031145 anaphase-promoting complex-dependent catabolic process IDA
 biological_processGO:0035519 protein K29-linked ubiquitination IDA
 biological_processGO:0044314 protein K27-linked ubiquitination IDA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0070534 protein K63-linked ubiquitination IDA
 biological_processGO:0070979 protein K11-linked ubiquitination IDA
 biological_processGO:0085020 protein K6-linked ubiquitination IDA
 biological_processGO:1904668 positive regulation of ubiquitin protein ligase activity IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005680 anaphase-promoting complex IDA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IBA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA
 molecular_functionGO:0061631 ubiquitin conjugating enzyme activity IDA


Pathways (from Reactome)
Pathway description
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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