ENSDARG00000031775


Danio rerio

Features
Gene ID: ENSDARG00000031775
  
Biological name :ube2s
  
Synonyms : Q4V908 / ube2s / ubiquitin-conjugating enzyme E2S
  
Possible biological names infered from orthology : Q16763 / Q921J4
  
Species: Danio rerio
  
Chr. number: 16
Strand: -1
Band:
Gene start: 13672768
Gene end: 13680692
  
Corresponding Affymetrix probe sets: Dr.14654.1.S1_at (Zebrafish Array)   Dr.17970.1.S1_at (Zebrafish Array)   NM_001025536_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000047451
NCBI entrez gene - 565498     See in Manteia.
RefSeq - NM_001025536
RefSeq Peptide - NP_001020707
swissprot - Q4V908
ZFIN ID - ZDB-GENE-050913-92
Ensembl - ENSDARG00000031775
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 UBE2SENSG00000108106Homo sapiens
 Ube2sENSMUSG00000060860Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ube2d4 / ubiquitin-conjugating enzyme E2D 4 (putative) / Q9Y2X8*ENSDARG0000001505724
ube2d1a / ubiquitin-conjugating enzyme E2D 1aENSDARG0000002910723
ube2d3 / ubiquitin-conjugating enzyme E2D 3ENSDARG0000003847323
ube2d2 / ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) / P62838* / P62837* / Ube2d2a* / ubiquitin conjugating enzyme E2 D2* / ubiquitin-conjugating enzyme E2D 2A*ENSDARG0000004348423
ube2d1b / ubiquitin-conjugating enzyme E2D 1b / UBE2D1* / P51668* / P61080* / ubiquitin conjugating enzyme E2 D1*ENSDARG0000003857623
ube2d2l / ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast), likeENSDARG0000009974923
rpl15 / ube2e1 / ubiquitin-conjugating enzyme E2E 1 / Q96LR5* / P51965* / UBE2E2* / ubiquitin conjugating enzyme E2 E2*ENSDARG0000011664922
ube2e3 / ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast) / P52483* / Q969T4* / ubiquitin conjugating enzyme E2 E3*ENSDARG0000001224422
ube2e2 / ubiquitin-conjugating enzyme E2E 2 / Q91W82* / Q96LR5* / UBE2E1* / P52482* / P51965* / ubiquitin conjugating enzyme E2 E1*ENSDARG0000003467022
ube2l3b / ubiquitin-conjugating enzyme E2L 3b / UBE2L3* / P68036* / P68037* / UBE2L5* / ubiquitin conjugating enzyme E2 L3* / ubiquitin conjugating enzyme E2 L5*ENSDARG0000002714119
ube2l3a / ubiquitin-conjugating enzyme E2L 3a / UBE2L5* / P68036* / UBE2L3* / ubiquitin conjugating enzyme E2 L3* / ubiquitin conjugating enzyme E2 L5*ENSDARG0000011208719


Protein motifs (from Interpro)
Interpro ID Name
 IPR000608  Ubiquitin-conjugating enzyme E2
 IPR016135  Ubiquitin-conjugating enzyme/RWD-like
 IPR023313  Ubiquitin-conjugating enzyme, active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IBA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IBA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0010458 exit from mitosis ISS
 biological_processGO:0010994 free ubiquitin chain polymerization ISS
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0031145 anaphase-promoting complex-dependent catabolic process ISS
 biological_processGO:0051301 cell division IEA
 biological_processGO:0070979 protein K11-linked ubiquitination ISS
 biological_processGO:1904668 positive regulation of ubiquitin protein ligase activity ISS
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005680 anaphase-promoting complex ISS
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity ISS
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IBA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA


Pathways (from Reactome)
Pathway description
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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