ENSG00000170035


Homo sapiens

Features
Gene ID: ENSG00000170035
  
Biological name :UBE2E3
  
Synonyms : Q969T4 / UBE2E3 / ubiquitin conjugating enzyme E2 E3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q31.3
Gene start: 180967248
Gene end: 181076585
  
Corresponding Affymetrix probe sets: 210024_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000473639
Ensembl peptide - ENSP00000473623
Ensembl peptide - ENSP00000473642
Ensembl peptide - ENSP00000376215
Ensembl peptide - ENSP00000386788
Ensembl peptide - ENSP00000473264
Ensembl peptide - ENSP00000473345
Ensembl peptide - ENSP00000473521
Ensembl peptide - ENSP00000473525
Ensembl peptide - ENSP00000473591
NCBI entrez gene - 10477     See in Manteia.
OMIM - 604151
RefSeq - XM_017003166
RefSeq - NM_001278554
RefSeq - NM_001278555
RefSeq - NM_006357
RefSeq - NM_182678
RefSeq - XM_005246244
RefSeq - XM_011510492
RefSeq Peptide - NP_006348
RefSeq Peptide - NP_872619
RefSeq Peptide - NP_001265483
RefSeq Peptide - NP_001265484
swissprot - R4GN77
swissprot - R4GND1
swissprot - R4GNG6
swissprot - A0A1B0GX65
swissprot - Q969T4
swissprot - R4GMM6
Ensembl - ENSG00000170035
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ube2e3ENSDARG00000012244Danio rerio
 UBE2E3ENSGALG00000020793Gallus gallus
 P52483ENSMUSG00000027011Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q96LR5 / UBE2E2 / ubiquitin conjugating enzyme E2 E2ENSG0000018224785
P51965 / UBE2E1 / ubiquitin conjugating enzyme E2 E1ENSG0000017014278
P62837 / UBE2D2 / ubiquitin conjugating enzyme E2 D2ENSG0000013150845
Q9Y2X8 / UBE2D4 / ubiquitin conjugating enzyme E2 D4 (putative)ENSG0000007896744
P61077 / UBE2D3 / ubiquitin conjugating enzyme E2 D3ENSG0000010933243
P51668 / UBE2D1 / ubiquitin conjugating enzyme E2 D1ENSG0000007240143
UBE2S / Q16763 / ubiquitin conjugating enzyme E2 SENSG0000010810625
UBE2L5 / ubiquitin conjugating enzyme E2 L5ENSG0000023644425
P68036 / UBE2L3 / ubiquitin conjugating enzyme E2 L3ENSG0000018565124
O14933 / UBE2L6 / ubiquitin conjugating enzyme E2 L6ENSG0000015658722


Protein motifs (from Interpro)
Interpro ID Name
 IPR000608  Ubiquitin-conjugating enzyme E2
 IPR016135  Ubiquitin-conjugating enzyme/RWD-like
 IPR023313  Ubiquitin-conjugating enzyme, active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination TAS
 biological_processGO:0040008 regulation of growth IEA
 biological_processGO:0070534 protein K63-linked ubiquitination IDA
 biological_processGO:0070936 protein K48-linked ubiquitination IDA
 biological_processGO:0070979 protein K11-linked ubiquitination IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0061631 ubiquitin conjugating enzyme activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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