ENSMUSG00000039092


Mus musculus

Features
Gene ID: ENSMUSG00000039092
  
Biological name :Sptlc3
  
Synonyms : Mus musculus serine palmitoyltransferase, long chain base subunit 3 (Sptlc3), transcript variant 1, mRNA. / Q8BG54 / Sptlc3
  
Possible biological names infered from orthology : Q9NUV7 / serine palmitoyltransferase long chain base subunit 3
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: F3
Gene start: 139493913
Gene end: 139637674
  
Corresponding Affymetrix probe sets: 10476545 (MoGene1.0st)   1439492_at (Mouse Genome 430 2.0 Array)   1446310_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000048313
Ensembl peptide - ENSMUSP00000105710
NCBI entrez gene - 228677     See in Manteia.
MGI - MGI:2444678
RefSeq - XM_006499295
RefSeq - NM_001356507
RefSeq - NM_175467
RefSeq Peptide - NP_780676
RefSeq Peptide - NP_001343436
swissprot - Q8BG54
Ensembl - ENSMUSG00000039092
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sptlc3ENSDARG00000030743Danio rerio
 SPTLC3ENSGALG00000009037Gallus gallus
 Q9NUV7ENSG00000172296Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P97363 / Sptlc2 / serine palmitoyltransferase, long chain base subunit 2 / O15270*ENSMUSG0000002103657


Protein motifs (from Interpro)
Interpro ID Name
 IPR001917  Aminotransferase, class-II, pyridoxal-phosphate binding site
 IPR004839  Aminotransferase, class I/classII
 IPR015421  Pyridoxal phosphate-dependent transferase, major domain
 IPR015422  Pyridoxal phosphate-dependent transferase domain 1
 IPR015424  Pyridoxal phosphate-dependent transferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006665 sphingolipid metabolic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009058 biosynthetic process IEA
 biological_processGO:0046520 sphingoid biosynthetic process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0017059 serine C-palmitoyltransferase complex IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004758 serine C-palmitoyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA


Pathways (from Reactome)
Pathway description
Sphingolipid de novo biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000043461 Q925E8 / Sptssb / Serine palmitoyltransferase small subunit B / Q8NFR3*  / complex
 ENSMUSG00000044408 Q8R207 / Sptssa / Serine palmitoyltransferase small subunit A / Q969W0*  / complex
 ENSMUSG00000021468 O35704 / Sptlc1 / Serine palmitoyltransferase 1 / O15269* / serine palmitoyltransferase long chain base subunit 1*  / complex






 

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