Manteia

ENSMUSG00000039826

Mus musculus

Features

Gene ID:	ENSMUSG00000039826

Biological name :	Trub2

Synonyms :	Q91WG3 / Trub2 / TruB pseudouridine (psi) synthase family member 2

Possible biological names infered from orthology :	O95900 / TruB pseudouridine synthase family member 2

Species:	Mus musculus

Chr. number:	2
Strand:	-1
Band:	B
Gene start:	29761224
Gene end:	29788502

Corresponding Affymetrix probe sets:	10481368 (MoGene1.0st) 1424610_at (Mouse Genome 430 2.0 Array) 1424611_x_at (Mouse Genome 430 2.0 Array) 1451408_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000109438 Ensembl peptide - ENSMUSP00000135521 Ensembl peptide - ENSMUSP00000041848 Ensembl peptide - ENSMUSP00000135893 Ensembl peptide - ENSMUSP00000134787 Ensembl peptide - ENSMUSP00000135464 NCBI entrez gene - 227682 See in Manteia. MGI - MGI:2442186 RefSeq - NM_145520 RefSeq - XM_006497925 RefSeq - XM_006497924 RefSeq - NM_001290495 RefSeq - NM_001290496 RefSeq Peptide - NP_001277424 RefSeq Peptide - NP_001277425 RefSeq Peptide - NP_663495 swissprot - H3BLS1 swissprot - Q91WG3 swissprot - H3BKT7 swissprot - A2ARC1 Ensembl - ENSMUSG00000039826

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Trub1 / Q8C0D0 / Probable tRNA pseudouridine synthase 1 / Q8WWH5* / TruB pseudouridine synthase family member 1*	ENSMUSG00000025086	25

Protein motifs (from Interpro)

Interpro ID	Name
IPR002501	Pseudouridine synthase II, N-terminal
IPR020103	Pseudouridine synthase, catalytic domain superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0001522	pseudouridine synthesis	IEA
biological_process	GO:0006396	RNA processing	IEA
biological_process	GO:0006397	mRNA processing	IEA
biological_process	GO:0008033	tRNA processing	IEA
biological_process	GO:0008150	biological_process	ND
biological_process	GO:0009451	RNA modification	IEA
cellular_component	GO:0005739	mitochondrion	IEA
cellular_component	GO:0005759	mitochondrial matrix	IEA
cellular_component	GO:0005829	cytosol	IEA
molecular_function	GO:0003723	RNA binding	IEA
molecular_function	GO:0009982	pseudouridine synthase activity	IEA
molecular_function	GO:0016853	isomerase activity	IEA

Pathways (from Reactome)

Pathway description

No match

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0001556	increased circulating HDL cholesterol level	"higher than average level of high density lipoprotein in the blood; this molecule transports cholesterol to the liver for excretion in bile" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:47439]	Show Allelic Composition: Tcf7l2^{tm1a(EUCOMM)Wtsi}/Tcf7l2⁺ Genetic Background: C57BL/6N-Tcf7l2^{tm1a(EUCOMM)Wtsi}/Wtsi
MP:0005178	increased total circulating cholesterol level	"greater than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Tcf7l2^{tm1a(EUCOMM)Wtsi}/Tcf7l2⁺ Genetic Background: C57BL/6N-Tcf7l2^{tm1a(EUCOMM)Wtsi}/Wtsi
MP:0011100	complete preweaning lethality	"death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]	Show Allelic Composition: Sufu^{tm1b(KOMP)Wtsi}/Sufu^{tm1b(KOMP)Wtsi} Genetic Background: C57BL/6N-Sufu^{tm1b(KOMP)Wtsi}/Ucd

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr