ENSMUSG00000040183


Mus musculus

Features
Gene ID: ENSMUSG00000040183
  
Biological name :Ankrd6
  
Synonyms : Ankrd6 / Mus musculus ankyrin repeat domain 6 (Ankrd6), transcript variant 4, mRNA. / Q69ZU8
  
Possible biological names infered from orthology : ankyrin repeat domain 6 / Q9Y2G4
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: A5
Gene start: 32804035
Gene end: 32950841
  
Corresponding Affymetrix probe sets: 10511901 (MoGene1.0st)   1421386_at (Mouse Genome 430 2.0 Array)   1437217_at (Mouse Genome 430 2.0 Array)   1450227_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000081800
Ensembl peptide - ENSMUSP00000081802
Ensembl peptide - ENSMUSP00000103801
Ensembl peptide - ENSMUSP00000041300
Ensembl peptide - ENSMUSP00000081801
NCBI entrez gene - 140577     See in Manteia.
MGI - MGI:2154278
RefSeq - XM_011249924
RefSeq - NM_001012450
RefSeq - NM_001012451
RefSeq - NM_001355587
RefSeq - NM_080471
RefSeq - XM_006537608
RefSeq - XM_011249919
RefSeq - XM_011249920
RefSeq - XM_011249921
RefSeq - XM_011249922
RefSeq - XM_011249923
RefSeq Peptide - NP_001012453
RefSeq Peptide - NP_001012454
RefSeq Peptide - NP_001342516
RefSeq Peptide - NP_536719
swissprot - Q69ZU8
swissprot - A2ANY8
Ensembl - ENSMUSG00000040183
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ankrd6aENSDARG00000057790Danio rerio
 ankrd6bENSDARG00000029370Danio rerio
 ANKRD6ENSGALG00000015768Gallus gallus
 ANKRD6ENSG00000135299Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Anks1 / P59672 / Ankyrin repeat and SAM domain-containing protein 1A / Q92625* / ANKS1A* / ankyrin repeat and sterile alpha motif domain containing 1A*ENSMUSG0000002421921
Q6P9K8 / Caskin1 / Q8WXD9* / CASK interacting protein 1*ENSMUSG0000003359720
Q8VHK1 / Caskin2 / Q8WXE0* / CASK interacting protein 2*ENSMUSG0000003447120
Mib1 / Q80SY4 / E3 ubiquitin-protein ligase MIB1 / Q86YT6* / mindbomb E3 ubiquitin protein ligase 1*ENSMUSG0000002429414
Mib2 / Q8R516 / E3 ubiquitin-protein ligase MIB2 / Q96AX9* / mindbomb E3 ubiquitin protein ligase 2*ENSMUSG0000002906014
Q14DN9 / Ankdd1b / Ankyrin repeat and death domain-containing protein 1B / A6NHY2* / ankyrin repeat and death domain containing 1B*ENSMUSG0000004711713
Ankdd1a / ankyrin repeat and death domain containing 1A / Q495B1*ENSMUSG0000006651013
Anks1b / ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform 6 / Q7Z6G8* / ankyrin repeat and sterile alpha motif domain containing 1B*ENSMUSG000000585895


Protein motifs (from Interpro)
Interpro ID Name
 IPR002110  Ankyrin repeat
 IPR020683  Ankyrin repeat-containing domain
 IPR036770  Ankyrin repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0046330 positive regulation of JNK cascade IBA
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IGI
 biological_processGO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle ISO
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001144 fused vaginal opening "condition in which the external vaginal opening is closed by the adherence of the epithelium of the vagina" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ankrd6tm1Pche/Ankrd6tm1Pche,Vangl2Lp/Vangl2+
Genetic Background: involves: 129 * LPT/LeJ

 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
Show

Allelic Composition: Fgf10tm1Ska/Fgf10+,Fgf8tm1Moon/Fgf8tm1Moon,Mesp1tm2(cre)Ysa/Mesp1+
Genetic Background: involves: C57BL/6NCrlj * CBA/JNCrlj

 MP:0002622 abnormal cochlear hair cell morphology "malformation of the sensory epithelial cells of the cochlea; these cells are in synaptic contact with the auditory nerve" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Ankrd6tm1Pche/Ankrd6tm1Pche,Vangl2Lp/Vangl2+
Genetic Background: involves: 129 * LPT/LeJ

 MP:0002623 abnormal vestibular hair cell morphology "malformation of the sensory epithelial cells of the membraneous labyrinth of the inner ear; these cells are in synaptic contact with the vestibular nerve" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Fgf10tm1Ska/Fgf10+,Fgf8tm1Moon/Fgf8tm1Moon,Mesp1tm2(cre)Ysa/Mesp1+
Genetic Background: involves: C57BL/6NCrlj * CBA/JNCrlj

 MP:0004399 abnormal cochlear outer hair cell morphology "any structural abnormality in the sensory cells of the organ of Corti which are in synaptic contact with sensory as well as efferent fibers of the auditory nerve; there are three rows of columnar outer hair cells largely surrounded by cortilymph and supporting phalangeal cells; the apical end of each cell is anchored to the cuticular plate and about 100 stereocilia arranged in a V-shaped pattern extend from the cell s surface through the cuticular plate into the tectorial membrane" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ankrd6tm1Pche/Ankrd6tm1Pche,Vangl2Lp/Vangl2+
Genetic Background: involves: 129 * LPT/LeJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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