Manteia

ID	Phenotype	Definition	Genetic BG
MP:0000743	muscle spasms	"muscular twitching, cramps and seizures ; frequently associated with calcium deficiency, hypoparathyroidism, vitamin D deficiency or alkalosis " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: S1pr1^tm1Rlp/S1pr1^tm1Rlp Genetic Background: involves: 129S6/SvEvTac
MP:0000745	tremors	"repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Psen1^tm1Vln/Psen1^tm1Vln,Tg(Thy1-APPLon)2Vln/0,Tg(Thy1-cre)1Vln/0 Genetic Background: involves: FVB/N Allelic Composition: Reln^rl-6J/Reln^rl-6J Genetic Background: C57BL/6J-Reln^rl-6J/J Allelic Composition: Reln^rl/Reln^rl Genetic Background: B6.Cg-Reln^rl Allelic Composition: Reln^rl-od/Reln^rl-od Genetic Background: involves: C57BL/6 * DBA/2 Allelic Composition: Reln^rl-tg/Reln^rl-tg Genetic Background: involves: C3H * C57BL/6 * DBA/2 Allelic Composition: Reln^rl-Alb2/Reln^rl-Alb2 Genetic Background: involves: C3H/HeJ * C57BL/6J Allelic Composition: Reln^rl-Alb/Reln^rl-Alb Genetic Background: involves: 101 * C3Hf/Rl
MP:0000788	abnormal cerebral cortex morphology	"malformed gray cellular mantle covering the surface of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:38857]	Show Allelic Composition: Cxcr2^tm1Mwm/Cxcr2^tm1Mwm Genetic Background: C.129S2(B6)-Cxcr2^tm1Mwm/J Allelic Composition: Reln^rl/Reln^rl Genetic Background: C3.Cg-Reln^rl Allelic Composition: Reln^rl-7J/Reln^rl-7J Genetic Background: C57BL/6J-Reln^rl-7J/GrsrJ Allelic Composition: Reln^rl-8J/Reln^rl-8J Genetic Background: STOCK Reln^rl-8J/J Allelic Composition: Reln^tm1.1Mhat/Reln^tm1.1Mhat Genetic Background: B6NSlc.B6(Cg)-Reln^tm1.1Mhat
MP:0000790	abnormal stratification in cerebral cortex	"abnormal formation or pattern of the layers of the cerebral cortex " [J:64289, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Reln^rl-5J/Reln^rl-5J Genetic Background: C3Fe(SWV) Mbp^shi-Reln^rl-5J/GrsrJ Allelic Composition: Reln^rl-6J/Reln^rl-6J Genetic Background: C57BL/6J-Reln^rl-6J/J Allelic Composition: Reln^rl/Reln^rl Genetic Background: C3.Cg-Reln^rl Allelic Composition: Reln^rl-7J/Reln^rl-7J Genetic Background: C57BL/6J-Reln^rl-7J/GrsrJ Allelic Composition: Reln^rl-4J/Reln^rl-4J Genetic Background: B6.Cg-Reln^rl-4J/GrsrJ Allelic Composition: Reln^rl-od/Reln^rl-od Genetic Background: involves: C57BL/6 * DBA/2 Allelic Composition: Reln^ctrdel/Reln^ctrdel,Rgs4^tm1Dgen/Rgs4⁺ Genetic Background: involves: 129P2/OlaHsd * A/J * C57BL/6
MP:0000792	abnormal cortical marginal zone morphology		Show Allelic Composition: Rag2^tm1.1Cgn/Rag2^tm1.1Cgn Genetic Background: C57BL/6-Rag2^tm1.1Cgn Allelic Composition: Dab1^tm1Cpr/Dab1^tm4Cpr,Reln^rl/Reln⁺ Genetic Background: involves: 129/Sv * C3HeB/Fe * C57BL/6 Allelic Composition: Reln^rl-5J/Reln^rl-5J Genetic Background: C3Fe(SWV) Mbp^shi-Reln^rl-5J/GrsrJ Allelic Composition: Reln^tm1.1Mhat/Reln^tm1.1Mhat Genetic Background: B6NSlc.B6(Cg)-Reln^tm1.1Mhat
MP:0000807	abnormal hippocampus morphology	"absent or malformed deep lying structure of the cerebrum involved with memory storage and spatial navigation" [The Atlas of Mouse Development:ISBN 0-12-402035-6, MGI:Cls, J:38857]	Show Allelic Composition: Msx1^tm1Rilm/Msx1^tm1Rilm,Msx2^tm1Rilm/Msx2^tm1Rilm Genetic Background: involves: 129S4/SvJae * BALB/c * CD-1 Allelic Composition: Reln^rl/Reln^rl Genetic Background: C3.Cg-Reln^rl Allelic Composition: Reln^rl/Reln^rl Genetic Background: B6.Cg-Reln^rl Allelic Composition: Reln^rl-7J/Reln^rl-7J Genetic Background: C57BL/6J-Reln^rl-7J/GrsrJ Allelic Composition: Reln^rl-od/Reln^rl-od Genetic Background: involves: C57BL/6 * DBA/2 Allelic Composition: Reln^rl-8J/Reln^rl-8J Genetic Background: STOCK Reln^rl-8J/J Allelic Composition: Reln^tm1.1Mhat/Reln^tm1.1Mhat Genetic Background: B6NSlc.B6(Cg)-Reln^tm1.1Mhat
MP:0000812	abnormal dentate gyrus morphology	"absence or malformation of one of two interlocking gyri of the hippocampus that contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:38857]	Show Allelic Composition: Rag2^tm1.1Cgn/Rag2^tm1.1Cgn Genetic Background: C57BL/6-Rag2^tm1.1Cgn Allelic Composition: Reln^rl/Reln^rl Genetic Background: C3.Cg-Reln^rl Allelic Composition: Reln^rl/Reln^rl Genetic Background: B6.Cg-Reln^rl Allelic Composition: Reln^rl-od/Reln^rl-od Genetic Background: involves: C57BL/6 * DBA/2 Allelic Composition: Reln^rl-8J/Reln^rl-8J Genetic Background: STOCK Reln^rl-8J/J Allelic Composition: Reln^tm1.1Mhat/Reln^tm1.1Mhat Genetic Background: B6NSlc.B6(Cg)-Reln^tm1.1Mhat
MP:0000813	abnormal hippocampal laminar structure	"malformed or missing layers of the laminar structure of the hippocampus" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:38857]	Show Allelic Composition: Reln^rl-5J/Reln^rl-5J Genetic Background: C3Fe(SWV) Mbp^shi-Reln^rl-5J/GrsrJ Allelic Composition: Reln^rl-4J/Reln^rl-4J Genetic Background: B6.Cg-Reln^rl-4J/GrsrJ
MP:0000819	abnormal olfactory bulb morphology	"malformation or absence of the forebrain region that coordinates neuronal signaling involved in the perception of smell; it receives input from the sensory neurons and outputs to the olfactory cortex" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, Principles of Neural Science:ISBN 0-8385-8034-3, J:16461]	Show Allelic Composition: Dab1^tm1Cpr/Dab1^tm1Cpr Genetic Background: either: (involves: 129S4/SvJaeSor * BALB/c) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0000849	abnormal cerebellum morphology	"any malformation or absence of the part of the metencephalon that lies in the posterior cranial fossa dorsal to the pons and medulla that is concerned with the coordination of movement and learning of motor skills" [J:50311, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]	Show Allelic Composition: Cxcr2^tm1Mwm/Cxcr2^tm1Mwm Genetic Background: C.129S2(B6)-Cxcr2^tm1Mwm/J
MP:0000852	small cerebellum	"reduced size of cerebellum" [MGI:CLS, J:17203, J:67524]	Show Allelic Composition: Cxcr2^tm1Mwm/Cxcr2^tm1Mwm Genetic Background: C.129S2(B6)-Cxcr2^tm1Mwm/J Allelic Composition: Reln^rl-5J/Reln^rl-5J Genetic Background: C3Fe(SWV) Mbp^shi-Reln^rl-5J/GrsrJ Allelic Composition: Reln^rl-6J/Reln^rl-6J Genetic Background: C57BL/6J-Reln^rl-6J/J Allelic Composition: Reln^rl/Reln⁺ Genetic Background: involves: BALB/c Allelic Composition: Reln^rl-7J/Reln^rl-7J Genetic Background: C57BL/6J-Reln^rl-7J/GrsrJ Allelic Composition: Reln^rl-4J/Reln^rl-4J Genetic Background: B6.Cg-Reln^rl-4J/GrsrJ Allelic Composition: Reln^rl-8J/Reln^rl-8J Genetic Background: STOCK Reln^rl-8J/J Allelic Composition: Reln^rl-tg/Reln^rl-tg Genetic Background: involves: C3H * C57BL/6 * DBA/2 Allelic Composition: Reln^rl-Alb/Reln^rl-Alb Genetic Background: involves: 101 * C3Hf/Rl
MP:0000853	absent cerebellar foliation	"missing small branches of the cerebellar lobules" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3, tc:Teresa Chu , Mouse Genome Informatics Curator, J:60896]	Show Allelic Composition: Reln^rl-tg/Reln^rl-tg Genetic Background: involves: C3H * C57BL/6 * DBA/2
MP:0000854	abnormal cerebellum development	"malformed or incomplete differentiation of the part of the metencephalon that lies dorsal to the pons and medulla behind the brain stem and controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Reln^rl-6J/Reln^rl-6J Genetic Background: C57BL/6J-Reln^rl-6J/J
MP:0000872	abnormal external granule cell layer	"malformation of the transient layer of the cerebellar cortex which is composed of the dividing and migrating granule cells" [tc:Teresa Chu , Mouse Genome Informatics Curator]	Show Allelic Composition: Reln^rl-Alb/Reln^rl-Alb Genetic Background: involves: 101 * C3Hf/Rl
MP:0000875	abnormal cerebellar Purkinje cell layer	"any malformation or absence of the cell layer that lies just underneath the molecular layer of the cerebellar cortex; it contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer, and candelabrum interneurons are vertically oriented between the Purkinje cells" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Reln^rl-7J/Reln^rl-7J Genetic Background: C57BL/6J-Reln^rl-7J/GrsrJ Allelic Composition: Reln^rl-4J/Reln^rl-4J Genetic Background: B6.Cg-Reln^rl-4J/GrsrJ Allelic Composition: Reln^rl-od/Reln^rl-od Genetic Background: involves: C57BL/6 * DBA/2
MP:0000876	Purkinje cell degeneration	"a retrogressive impairment of function or destruction of the large neurons located at the interface of the molecular and internal granule layers of the cerebellar cortex" [J:46854]	Show Allelic Composition: Fgf8^tm1.2Mrt/Fgf8^tm1.3Mrt,Foxg1^tm1(cre)Skm/Foxg1⁺ Genetic Background: involves: 129P2/OlaHsd
MP:0000877	abnormal Purkinje cell	"any structural anomaly of the neurons located at the interface of the molecular and internal granule layers of the cerebellar cortex; these inhibitory neurons provide the output of the cerebellar cortex through axons that project into the white matter, and extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells" [J:46140, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]	Show Allelic Composition: Reln^rl-Alb/Reln^rl-Alb Genetic Background: involves: 101 * C3Hf/Rl
MP:0000880	decreased Purkinje cell number	"fewer than normal neuronal cells that are located in the interface of the molecular and granular layers of the cerebellar cortex" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:45302]	Show Allelic Composition: Fgf8^tm1.2Mrt/Fgf8^tm1.3Mrt,Foxg1^tm1(cre)Skm/Foxg1⁺ Genetic Background: involves: 129P2/OlaHsd Allelic Composition: Reln^rl-Alb/Reln^rl-Alb Genetic Background: involves: 101 * C3Hf/Rl
MP:0000884	delaminated Purkinje cell layer	"splitting or disorganization of the layer of large neuron cell bodies between the molecular and granular layers of the cerebellum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61509]	Show Allelic Composition: Reln^rl-5J/Reln^rl-5J Genetic Background: C3Fe(SWV) Mbp^shi-Reln^rl-5J/GrsrJ
MP:0000885	ectopic Purkinje cell	"Purkinje cell body resides in places other than the Purkinje cell layer in the cerebellum" [MGI:tc, J:60896]	Show Allelic Composition: Reln^rl-Alb/Reln^rl-Alb Genetic Background: involves: 101 * C3Hf/Rl
MP:0000886	abnormal cerebellar granule layer	"any malformation or absence of the innermost cortical layer of the cerebellum; contains densly packed small neurons, mostly granule cells with some Golgi cells are found at the outer border" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]	Show Allelic Composition: Reln^rl-4J/Reln^rl-4J Genetic Background: B6.Cg-Reln^rl-4J/GrsrJ
MP:0000887	delaminated granule layer	"splitting or disorganization of the deepest of the three layers of the cerebellum that contains granule cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61509]	Show Allelic Composition: Reln^rl-5J/Reln^rl-5J Genetic Background: C3Fe(SWV) Mbp^shi-Reln^rl-5J/GrsrJ
MP:0000968	abnormal sensory neuron innervation	"defective or incomplete supply of nerve fibers to sensory termini or to spinal cord" [J:31622]	Show Allelic Composition: Reln^rl/Reln^rl Genetic Background: C3.Cg-Reln^rl Allelic Composition: Reln^rl/Reln^rl Genetic Background: B6.Cg-Reln^rl
MP:0001262	decreased body weight	"lower than normal average weight " [J:61295]	Show Allelic Composition: Reln^rl/Reln^rl Genetic Background: B6.Cg-Reln^rl Allelic Composition: Reln^rl-od/Reln^rl-od Genetic Background: involves: C57BL/6 * DBA/2
MP:0001265	reduced body size	"smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]	Show Allelic Composition: Psen1^tm1Vln/Psen1^tm1Vln,Tg(Thy1-APPLon)2Vln/0,Tg(Thy1-cre)1Vln/0 Genetic Background: involves: FVB/N Allelic Composition: Reln^rl-4J/Reln^rl-4J Genetic Background: B6.Cg-Reln^rl-4J/GrsrJ Allelic Composition: Reln^rl-Alb/Reln^rl-Alb Genetic Background: involves: 101 * C3Hf/Rl Allelic Composition: Reln^m1Anu/Reln^m1Anu Genetic Background: C57BL/6JAnu-Reln^m1Anu
MP:0001360	abnormal social investigation	"altered behavior of animals to approach and examine other animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Meis1^tm1Mtor/Meis1^tm1Mtor Genetic Background: Not Specified
MP:0001393	ataxia	"inability to coordinate voluntary muscular movements" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67231]	Show Allelic Composition: Agtpbp1^pcd-7J/Agtpbp1^pcd-7J Genetic Background: C.Cg-Igh-6^tm1Cgn Agtpbp1^pcd-7J Allelic Composition: Reln^rl/Reln^rl Genetic Background: C3.Cg-Reln^rl Allelic Composition: Reln^rl/Reln^rl Genetic Background: B6.Cg-Reln^rl Allelic Composition: Reln^rl-7J/Reln^rl-7J Genetic Background: C57BL/6J-Reln^rl-7J/GrsrJ Allelic Composition: Reln^rl-4J/Reln^rl-4J Genetic Background: B6.Cg-Reln^rl-4J/GrsrJ Allelic Composition: Reln^rl-od/Reln^rl-od Genetic Background: involves: C57BL/6 * DBA/2 Allelic Composition: Reln^rl-8J/Reln^rl-8J Genetic Background: STOCK Reln^rl-8J/J Allelic Composition: Reln^rl-tg/Reln^rl-tg Genetic Background: involves: C3H * C57BL/6 * DBA/2 Allelic Composition: Reln^rl-Alb/Reln^rl-Alb Genetic Background: involves: 101 * C3Hf/Rl
MP:0001402	hypoactivity	"reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]	Show Allelic Composition: Psen1^tm1Vln/Psen1^tm1Vln,Tg(Thy1-APPLon)2Vln/0,Tg(Thy1-cre)1Vln/0 Genetic Background: involves: FVB/N Allelic Composition: Reln^rl/Reln^rl Genetic Background: B6.Cg-Reln^rl Allelic Composition: Reln^rl-od/Reln^rl-od Genetic Background: involves: C57BL/6 * DBA/2
MP:0001405	impaired coordination	"reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Reln^m1Anu/Reln^m1Anu Genetic Background: C57BL/6JAnu-Reln^m1Anu
MP:0001406	abnormal gait	"unusual or distinctive way of walking" [J:65038]	Show Allelic Composition: Psen1^tm1Vln/Psen1^tm1Vln,Tg(Thy1-APPLon)2Vln/0,Tg(Thy1-cre)1Vln/0 Genetic Background: involves: FVB/N Allelic Composition: Reln^rl/Reln^rl Genetic Background: B6.Cg-Reln^rl Allelic Composition: Reln^rl-7J/Reln^rl-7J Genetic Background: C57BL/6J-Reln^rl-7J/GrsrJ Allelic Composition: Reln^rl-4J/Reln^rl-4J Genetic Background: B6.Cg-Reln^rl-4J/GrsrJ Allelic Composition: Reln^rl-8J/Reln^rl-8J Genetic Background: STOCK Reln^rl-8J/J Allelic Composition: Reln^rl-tg/Reln^rl-tg Genetic Background: involves: C3H * C57BL/6 * DBA/2
MP:0001504	abnormal posture	"atypical position of the limbs or carriage of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:18984]	Show Allelic Composition: Htr2c^tm1Knk/Htr2c^tm2Knk Genetic Background: B6.Cg-Htr2c^tm1Knk/Htr2c^tm2Knk
MP:0001511	disheveled coat	"coat that looks generally unkempt" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Psen1^tm1Vln/Psen1^tm1Vln,Tg(Thy1-APPLon)2Vln/0,Tg(Thy1-cre)1Vln/0 Genetic Background: involves: FVB/N
MP:0001516	abnormal motor coordination/ balance	"altered ability of an animal to maintain skillful and effective interaction of movements or maintenance of equilibrium" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Igf2r^tm1Arge/Igf2r⁺ Genetic Background: involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv
MP:0001523	impaired righting response	"reduced ability or greater amount of time needed to recover from supine position" [J:25565]	Show Allelic Composition: Reln^rl/Reln^rl Genetic Background: B6.Cg-Reln^rl Allelic Composition: Reln^rl-8J/Reln^rl-8J Genetic Background: STOCK Reln^rl-8J/J Allelic Composition: Reln^rl-Alb2/Reln^rl-Alb2 Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0001525	impaired balance	"reduced ability of an animal to maintain equilibrium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:64962, J:17123]	Show Allelic Composition: Psen1^tm1Vln/Psen1^tm1Vln,Tg(Thy1-APPLon)2Vln/0,Tg(Thy1-cre)1Vln/0 Genetic Background: involves: FVB/N Allelic Composition: Reln^rl-7J/Reln^rl-7J Genetic Background: C57BL/6J-Reln^rl-7J/GrsrJ Allelic Composition: Reln^rl-4J/Reln^rl-4J Genetic Background: B6.Cg-Reln^rl-4J/GrsrJ
MP:0001732	postnatal growth retardation	"slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Psen1^tm1Vln/Psen1^tm1Vln,Tg(Thy1-APPLon)2Vln/0,Tg(Thy1-cre)1Vln/0 Genetic Background: involves: FVB/N Allelic Composition: Reln^rl/Reln^rl Genetic Background: C3.Cg-Reln^rl Allelic Composition: Reln^rl/Reln^rl Genetic Background: B6.Cg-Reln^rl Allelic Composition: Reln^rl-od/Reln^rl-od Genetic Background: involves: C57BL/6 * DBA/2
MP:0001923	reduced female fertility	"reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]	Show Allelic Composition: Psen1^tm1Vln/Psen1^tm1Vln,Tg(Thy1-APPLon)2Vln/0,Tg(Thy1-cre)1Vln/0 Genetic Background: involves: FVB/N
MP:0001924	infertility	"inability to produce live offspring" [J:47225]	Show Allelic Composition: Reln^rl/Reln^rl Genetic Background: B6.Cg-Reln^rl
MP:0001925	male infertility	"inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]	Show Allelic Composition: Psen1^tm1Vln/Psen1^tm1Vln,Tg(Thy1-APPLon)2Vln/0,Tg(Thy1-cre)1Vln/0 Genetic Background: involves: FVB/N
MP:0002066	abnormal motor capabilities/coordination/movement	"altered ability to coordinate voluntary movement or repetitive, compulsive movements" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Spint1^tm1Bug/Spint1^tm1Bug,St14^tm1Bug/St14^tm1Bug Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * NIH Black Swiss
MP:0002082	postnatal lethality	"premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Igf2r^tm1Arge/Igf2r⁺ Genetic Background: involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv
MP:0002083	premature death	"death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Klf2^tm1Jml/Klf2^tm1Jml Genetic Background: either: (involves: 129X1/SvJ * C57BL/6) or (involves: 129X1/SvJ * C57BL/6 * CD-1) Allelic Composition: Reln^rl/Reln^rl Genetic Background: B6.Cg-Reln^rl Allelic Composition: Reln^rl-7J/Reln^rl-7J Genetic Background: C57BL/6J-Reln^rl-7J/GrsrJ Allelic Composition: Reln^rl-8J/Reln^rl-8J Genetic Background: STOCK Reln^rl-8J/J
MP:0002566	abnormal sexual interaction	"altered initiation, failure of initiation or incomplete mating behavior" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Agtpbp1^pcd/Agtpbp1^pcd Genetic Background: involves: C57BR/cdJ
MP:0003088	abnormal prepulse inhibition	"increase or decrease in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [smb:Susan M. Bello, Mouse Genome Informatics Curator, J:91131]	Show Allelic Composition: Meis1^tm1Mtor/Meis1^tm1Mtor Genetic Background: Not Specified
MP:0003651	abnormal axon outgrowth	"defect/abnormality in the ability of an axon to extend from a neuron cell body" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator, J:96121]	Show Allelic Composition: Hspa5^baffled/Hspa5^baffled,Tg(Mbp-MAPT/lacZ)#aCaw/Tg(Mbp-MAPT/lacZ)#aCaw Genetic Background: involves: BALB/c * C57BL/6 * C57BL/6J * FVB/N
MP:0003733	abnormal inner nuclear layer morphology	"malformation/anomalous structure of the retinal layer which contains the cell bodies of bipolar, horizontal, and amacrine cells" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]	Show Allelic Composition: Nudt1^tm1Tts/Nudt1^tm1Tts Genetic Background: B6.129S-Nudt1^tm1Tts
MP:0004021	abnormal rod electrophysiology	"anomaly in the function of dark adapted vision mediated by the rods" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Nudt1^tm1Tts/Nudt1^tm1Tts Genetic Background: B6.129S-Nudt1^tm1Tts
MP:0004022	abnormal cone electrophysiology	"anomaly in the function of light adapted vision mediated by the cones" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Nudt1^tm1Tts/Nudt1^tm1Tts Genetic Background: B6.129S-Nudt1^tm1Tts
MP:0004097	abnormal cerebellar cortex morphology	"any structural anomaly of the thin mantle of gray matter that covers the surface of each cerebral hemisphere, including the six layers of nerve cells and the nerve pathways that connect them; together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]	Show Allelic Composition: Reln^rl-4J/Reln^rl-4J Genetic Background: B6.Cg-Reln^rl-4J/GrsrJ Allelic Composition: Reln^rl-8J/Reln^rl-8J Genetic Background: STOCK Reln^rl-8J/J Allelic Composition: Reln^rl-tg/Reln^rl-tg Genetic Background: involves: C3H * C57BL/6 * DBA/2
MP:0004103	abnormal ventral striatum morphology	"any structural abnormality of the regions of the nucleus accumbens and some nuclei of the olfactory tubercule that lie ventral to the anterior commissure" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Adcy4^tm1.1Dek/Adcy4^tm1.1Dek,Tg(AQP2-cre)2Dek/0 Genetic Background: involves: C57BL/6 * CBA
MP:0004275	abnormal postnatal subventricular zone morphology	"any structural anomaly of the mitotically active layer of cells surrounding the brain ventricles in the adult that consists of migrating neuroblasts, astrocytes and transitory amplifying progenitor cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:12637172]	Show Allelic Composition: Dab1^tm1Cpr/Dab1^tm1Cpr Genetic Background: either: (involves: 129S4/SvJaeSor * BALB/c) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0004279	abnormal rostral migratory stream morphology	"any structural anomaly of the transient structure formed by neurons migrating from the subventricular zone into the olfactory bulbs" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dab1^tm1Cpr/Dab1^tm1Cpr Genetic Background: either: (involves: 129S4/SvJaeSor * BALB/c) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0005036	diarrhea	"abnormally frequent discharge of semi-solid or fluid fecal matter from the bowel" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Reln^rl/Reln^rl Genetic Background: C3.Cg-Reln^rl
MP:0005267	abnormal olfactory cortex morphology	"anomalous structure of piriform cortex, part of the olfactory tract, which receives its major afferents from the olfactory bulb, and is primarily responsible for the identification of odors" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83884]	Show Allelic Composition: Reln^rl/Reln^rl Genetic Background: C3.Cg-Reln^rl Allelic Composition: Reln^rl/Reln^rl Genetic Background: B6.Cg-Reln^rl
MP:0006009	abnormal neuronal migration	"defective or impaired movement of immature neurons from germinal zones to specific positions where they will reside as they mature" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Reln^rl/Reln^rl Genetic Background: C3.Cg-Reln^rl
MP:0006074	abnormal retinal rod bipolar cell morphology	"anomalous structure of the bipolar cells that function in low light and transmit signals only through amacrine cells" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:92623]	Show Allelic Composition: Nudt1^tm1Tts/Nudt1^tm1Tts Genetic Background: B6.129S-Nudt1^tm1Tts
MP:0006300	abnormal entorhinal cortex morphology	"any structural anomaly of the structure in the anterior parahippocampus that lies forward of the parahippocampal cortex and immediately medial to the perirhinal cortex, bounded superiorly by the hippocampus and inferiorly by the collateral sulcus" [brs:Beverly Richards-Smith_IMSR Curator]	Show Allelic Composition: Reln^rl/Reln^rl Genetic Background: C3.Cg-Reln^rl Allelic Composition: Reln^rl/Reln^rl Genetic Background: B6.Cg-Reln^rl
MP:0008031	decreased Cajal-Retzius cell number	"reduced number of the distinct population of large, bipolar cells, distributed in a continuous band along the marginal zone of the cortex extending to the molecular layer of the dentate gyrus" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]	Show Allelic Composition: Gt(ROSA)26Sor^tm1(DTA)Riet/Gt(ROSA)26Sor⁺,Reln^rl/Reln⁺,Trp73^tm1(cre)Agof/Trp73⁺ Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ Allelic Composition: Gt(ROSA)26Sor^tm1(DTA)Riet/Gt(ROSA)26Sor⁺,Reln^rl/Reln⁺,Wnt3a^tm1(cre)Eag/Wnt3a⁺ Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ Allelic Composition: Gt(ROSA)26Sor^tm1(DTA)Riet/Gt(ROSA)26Sor⁺,Reln^rl/Reln⁺,Trp73^tm1(cre)Agof/Trp73⁺,Wnt3a^tm1(cre)Eag/Wnt3a⁺ Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
MP:0008263	abnormal hippocampus CA1 region morphology		Show Allelic Composition: Reln^rl/Reln^rl Genetic Background: C3.Cg-Reln^rl Allelic Composition: Reln^rl/Reln^rl Genetic Background: B6.Cg-Reln^rl Allelic Composition: Reln^tm1.1Mhat/Reln^tm1.1Mhat Genetic Background: B6NSlc.B6(Cg)-Reln^tm1.1Mhat
MP:0008265	abnormal hippocampus CA2 region morphology		Show Allelic Composition: Reln^rl/Reln^rl Genetic Background: C3.Cg-Reln^rl Allelic Composition: Reln^rl/Reln^rl Genetic Background: B6.Cg-Reln^rl
MP:0008284	abnormal hippocampus pyramidal cell layer		Show Allelic Composition: Rag2^tm1.1Cgn/Rag2^tm1.1Cgn Genetic Background: C57BL/6-Rag2^tm1.1Cgn Allelic Composition: Reln^rl-tg/Reln^rl-tg Genetic Background: involves: C3H * C57BL/6 * DBA/2
MP:0008285	abnormal hippocampus granule cell layer		Show Allelic Composition: Reln^rl-tg/Reln^rl-tg Genetic Background: involves: C3H * C57BL/6 * DBA/2
MP:0008431	abnormal short-term spatial reference memory	"anomaly in the short-term memory for spatial location information that is established during the first few minutes after training or an encouter at that location" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Meis1^tm1Mtor/Meis1^tm1Mtor Genetic Background: Not Specified
MP:0008489	postnatal slow weight gain	"the weight gain over a span of postnatal developmental time is slower than controls, with or without ever attaining a similar weight to controls as adults" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Reln^rl/Reln^rl Genetic Background: C3.Cg-Reln^rl
MP:0008770	decreased survivor rate	"a smaller percentage of organisms than expected survive to adulthood and have a lifespan similar to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Reln^rl-Alb/Reln^rl-Alb Genetic Background: involves: 101 * C3Hf/Rl
MP:0009937	abnormal neuron differentiation	"abnormal growth or development of the cells of the nervous system that receive, conduct, and transmit impulses" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Cxcr2^tm1Mwm/Cxcr2^tm1Mwm Genetic Background: C.129S2(B6)-Cxcr2^tm1Mwm/J
MP:0009949	abnormal olfactory bulb granule cell layer morphology		Show Allelic Composition: Dab1^tm1Cpr/Dab1^tm1Cpr Genetic Background: either: (involves: 129S4/SvJaeSor * BALB/c) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0011083	complete lethality at weaning	"premature death at weaning age of all organisms of a given genotype in a population, often due to the inability to make the transition to solid food" [MGI:csmith]	Show Allelic Composition: Psen1^tm1Vln/Psen1^tm1Vln,Tg(Thy1-APPLon)2Vln/0,Tg(Thy1-cre)1Vln/0 Genetic Background: involves: FVB/N
MP:0011086	partial postnatal lethality	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]	Show Allelic Composition: Reln^rl-4J/Reln^rl-4J Genetic Background: B6.Cg-Reln^rl-4J/GrsrJ
MP:0011448	decreased dopaminergic neuron number	"fewer than normal numbers of the neurons that utilize dopamine as a neurotransmitter" [MGI:smb]	Show Allelic Composition: Adcy4^tm1.1Dek/Adcy4^tm1.1Dek,Tg(AQP2-cre)2Dek/0 Genetic Background: involves: C57BL/6 * CBA

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr

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