ENSMUSG00000043029


Mus musculus

Features
Gene ID: ENSMUSG00000043029
  
Biological name :Trpv3
  
Synonyms : Q8K424 / Transient receptor potential cation channel subfamily V member 3 / Trpv3
  
Possible biological names infered from orthology : Q8NET8
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: B4
Gene start: 73267388
Gene end: 73300363
  
Corresponding Affymetrix probe sets: 10378367 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000053755
NCBI entrez gene - 246788     See in Manteia.
MGI - MGI:2181407
RefSeq - XM_006533348
RefSeq - NM_145099
RefSeq - XM_006533347
RefSeq Peptide - NP_659567
swissprot - Q8K424
Ensembl - ENSMUSG00000043029
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TRPV3ENSGALG00000004660Gallus gallus
 TRPV3ENSG00000167723Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Trpv1 / Q704Y3 / Transient receptor potential cation channel subfamily V member 1 / Q8NER1*ENSMUSG0000000595240
Trpv4 / Q9EPK8 / Transient receptor potential cation channel subfamily V member 4 / Q9HBA0*ENSMUSG0000001415838
Trpv2 / Q9WTR1 / Transient receptor potential cation channel subfamily V member 2 / Q9Y5S1*ENSMUSG0000001850737
Trpv6 / Q91WD2 / transient receptor potential cation channel, subfamily V, member 6 / Q9H1D0*ENSMUSG0000002986824
Trpv5 / P69744 / Transient receptor potential cation channel subfamily V member 5 / Q9NQA5*ENSMUSG0000003689923


Protein motifs (from Interpro)
Interpro ID Name
 IPR002110  Ankyrin repeat
 IPR005821  Ion transport domain
 IPR008347  Transient receptor potential channel, vanilloid 1-4
 IPR020683  Ankyrin repeat-containing domain
 IPR024862  Transient receptor potential cation channel subfamily V
 IPR024866  Transient receptor potential channel, vanilloid 3
 IPR036770  Ankyrin repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0009266 response to temperature stimulus IDA
 biological_processGO:0009408 response to heat IEA
 biological_processGO:0042636 negative regulation of hair cycle IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 biological_processGO:0090280 positive regulation of calcium ion import IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043235 receptor complex IEA
 molecular_functionGO:0005216 ion channel activity IDA
 molecular_functionGO:0005261 cation channel activity IDA
 molecular_functionGO:0005262 calcium channel activity IBA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
TRP channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000367 abnormal coat/ hair morphology "anomalous color, structure, growth, or texture of the hair" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cecr2Gt(pGT1)1Hemc/Cecr2Gt(pGT1)1Hemc
Genetic Background: involves: C.129P2-Cecr2Gt(pGT1)1Hemc * FVB.129P2(C)-Cecr2Gt(pGT1)1Hemc

 MP:0000383 abnormal hair follicle orientation "misaligned hair follicles; hair follicles that do not orient in a typical pattern" [J:47620]
Show

Allelic Composition: Tfpitm1.1Rdsi/Tfpitm1.1Rdsi,Lyz2tm1(cre)Ifo/Lyz2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * 129S6/SvEvTac * BALB/cJ * C57BL/6

Allelic Composition: Trpv3tm1.2Clph/Trpv3tm1.2Clph
Genetic Background: involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6 * C57BL/6J * CBA

 MP:0000410 waved hair "hair or fur having undulations or a sinusoidal shape" [J:47620]
Show

Allelic Composition: Tfpitm1.1Rdsi/Tfpitm1.1Rdsi,Lyz2tm1(cre)Ifo/Lyz2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * 129S6/SvEvTac * BALB/cJ * C57BL/6

Allelic Composition: Trpv3tm1.2Clph/Trpv3tm1.2Clph
Genetic Background: B6.129S4-Trpv3tm1.2Clph

Allelic Composition: Trpv3tm1.2Clph/Trpv3tm1.2Clph
Genetic Background: involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6 * C57BL/6J * CBA

 MP:0001192 scaly skin "skin covered with shedding scales or flakes" [J:65146]
Show

Allelic Composition: Tfpitm1.1Rdsi/Tfpitm1.1Rdsi,Lyz2tm1(cre)Ifo/Lyz2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * 129S6/SvEvTac * BALB/cJ * C57BL/6

Allelic Composition: Trpv3tm1.2Clph/Trpv3tm1.2Clph
Genetic Background: involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6 * C57BL/6J * CBA

 MP:0001194 dermatitis "inflammation of the skin" [J:65146]
Show

Allelic Composition: Apoetm1Unc/Apoetm1Unc
Genetic Background: B6.129P2-Apoetm1Unc/J

 MP:0001240 abnormal cornified layer morphology "structural or developmental anomaly of the outer layer of the epidermis, consisting of several layers of flat keratinized non-nucleated cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Tfpitm1.1Rdsi/Tfpitm1.1Rdsi,Lyz2tm1(cre)Ifo/Lyz2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * 129S6/SvEvTac * BALB/cJ * C57BL/6

Allelic Composition: Trpv3tm1.2Clph/Trpv3tm1.2Clph
Genetic Background: involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6 * C57BL/6J * CBA

 MP:0001274 curly vibrissae "whiskers twisted into coils or spirals" [J:47620]
Show

Allelic Composition: Tfpitm1.1Rdsi/Tfpitm1.1Rdsi,Lyz2tm1(cre)Ifo/Lyz2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * 129S6/SvEvTac * BALB/cJ * C57BL/6

Allelic Composition: Trpv3tm1.2Clph/Trpv3tm1.2Clph
Genetic Background: B6.129S4-Trpv3tm1.2Clph

Allelic Composition: Trpv3tm1.2Clph/Trpv3tm1.2Clph
Genetic Background: involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6 * C57BL/6J * CBA

 MP:0001973 increased thermal nociceptive threshold "a greater than average point at which thermal pain sensation is first detectable" [What s Wrong With My Mouse?:ISBN 0-471-31639-3, J:17194]
Show

Allelic Composition: Cecr2Gt(pGT1)1Hemc/Cecr2Gt(pGT1)1Hemc
Genetic Background: involves: C.129P2-Cecr2Gt(pGT1)1Hemc * FVB.129P2(C)-Cecr2Gt(pGT1)1Hemc

 MP:0002073 abnormal hair growth "absence or reduced amount of hair or abnormal onset of hair growth cycle or development" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Apoetm1Unc/Apoetm1Unc
Genetic Background: B6.129P2-Apoetm1Unc/J

 MP:0002412 increased susceptibility to bacterial infection "greater likelihood that an organism will develop ill effects from a bacterial infection or from components of or toxins produced by bacteria" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Apoetm1Unc/Apoetm1Unc
Genetic Background: B6.129P2-Apoetm1Unc/J

 MP:0003453 abnormal keratinocyte physiology "atypical function of the cells of the epidermis that produce keratin" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator, J:94860]
Show

Allelic Composition: Cecr2Gt(pGT1)1Hemc/Cecr2Gt(pGT1)1Hemc
Genetic Background: involves: C.129P2-Cecr2Gt(pGT1)1Hemc * FVB.129P2(C)-Cecr2Gt(pGT1)1Hemc

Allelic Composition: Trpv3tm1.2Clph/Trpv3tm1.2Clph
Genetic Background: involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6 * C57BL/6J * CBA

 MP:0003454 erythroderma "exfoliation and widespread, intense reddening of the skin due to inflammatory skin disease" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:95549]
Show

Allelic Composition: Tfpitm1.1Rdsi/Tfpitm1.1Rdsi,Lyz2tm1(cre)Ifo/Lyz2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * 129S6/SvEvTac * BALB/cJ * C57BL/6

Allelic Composition: Trpv3tm1.2Clph/Trpv3tm1.2Clph
Genetic Background: involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6 * C57BL/6J * CBA

 MP:0003663 abnormal thermosensation "defect in the ability to sense or display a preference for a given temperature" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator, J:96549]
Show

Allelic Composition: Cecr2Gt(pGT1)1Hemc/Cecr2Gt(pGT1)1Hemc
Genetic Background: involves: C.129P2-Cecr2Gt(pGT1)1Hemc * FVB.129P2(C)-Cecr2Gt(pGT1)1Hemc

 MP:0003853 dry skin "skin characterized by the lack of natural or normal moisture" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Tfpitm1.1Rdsi/Tfpitm1.1Rdsi,Lyz2tm1(cre)Ifo/Lyz2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * 129S6/SvEvTac * BALB/cJ * C57BL/6

Allelic Composition: Trpv3tm1.2Clph/Trpv3tm1.2Clph
Genetic Background: involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6 * C57BL/6J * CBA

 MP:0009594 abnormal corneocyte envelope morphology "any structural or developmental anomaly of the electron-dense layer of highly transglutaminase cross-linked protein that is deposited on the inner surface of the plasma membrane of corneocytes in the outermost layers of the epidermis; a monomolecular layer of ceramides is covalently attached to the outer surface of the CE to form a hydrophobic lipid envelope that covers each corneocyte and provides continuity with the lipid matrix" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tfpitm1.1Rdsi/Tfpitm1.1Rdsi,Lyz2tm1(cre)Ifo/Lyz2+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * 129S6/SvEvTac * BALB/cJ * C57BL/6

Allelic Composition: Trpv3tm1.2Clph/Trpv3tm1.2Clph
Genetic Background: involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6 * C57BL/6J * CBA

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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