ENSMUSG00000043753


Mus musculus

Features
Gene ID: ENSMUSG00000043753
  
Biological name :Dmrta1
  
Synonyms : Dmrta1 / Doublesex- and mab-3-related transcription factor A1 / Q8CFG4
  
Possible biological names infered from orthology : DMRT like family A1 / Q5VZB9
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: C4
Gene start: 89679436
Gene end: 89694772
  
Corresponding Affymetrix probe sets: 10505911 (MoGene1.0st)   1441579_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000057488
NCBI entrez gene - 242523     See in Manteia.
MGI - MGI:2653627
RefSeq - NM_175647
RefSeq Peptide - NP_783578
swissprot - Q8CFG4
Ensembl - ENSMUSG00000043753
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DMRTA1ENSG00000176399Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A2A9A2 / Dmrta2 / Doublesex- and mab-3-related transcription factor A2 / Q96SC8* / DMRT like family A2*ENSMUSG0000004714336
Dmrt3 / Q80WT2 / Doublesex- and mab-3-related transcription factor 3 / Q9NQL9*ENSMUSG0000004237224
Dmrt2 / Q8BG36 / Doublesex- and mab-3-related transcription factor 2 / Q9Y5R5*ENSMUSG0000004813819
Dmrt1 / Q9QZ59 / Doublesex- and mab-3-related transcription factor 1 / Q9Y5R6*ENSMUSG0000002483717
Dmrtc2 / Q8CGW9 / Doublesex- and mab-3-related transcription factor C2 / Q8IXT2* / DMRT like family C2*ENSMUSG0000001134914
A2A9I7 / Dmrtb1 / Doublesex- and mab-3-related transcription factor B1 / Q96MA1* / DMRT like family B with proline rich C-terminal 1*ENSMUSG0000002861013
Dmrtc1b / DMRTC1* / Q5HYR2* / DMRT like family C1* / DMRT like family C1B*ENSMUSG000000730276
Q9D9R7 / Dmrtc1a / Doublesex- and mab-3-related transcription factor C1 / DMRTC1* / Q5HYR2* / DMRTC1B* / DMRT like family C1* / DMRT like family C1B*ENSMUSG000000313233


Protein motifs (from Interpro)
Interpro ID Name
 IPR001275  DM DNA-binding domain
 IPR005173  DMRTA motif
 IPR009060  UBA-like superfamily
 IPR026607  DMRT/protein doublesex/protein male abnormal 3
 IPR036407  DM DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001541 ovarian follicle development IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0060179 male mating behavior IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0043565 sequence-specific DNA binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001375 abnormal mating preference "deviation from the usual preference of a male to initiate sexual contact with a receptive female; usually refers to males that initiate sexual behavior with males and females indiscriminately" [J:76339]
Show

Allelic Composition: Ptgs2tm2.1(Ptgs1)Fun/Ptgs2tm2.1(Ptgs1)Fun
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB

 MP:0002566 abnormal sexual interaction "altered initiation, failure of initiation or incomplete mating behavior" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ptgs2tm2.1(Ptgs1)Fun/Ptgs2tm2.1(Ptgs1)Fun
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB

Allelic Composition: Dmrta1tm1.1Zark/Dmrta1+
Genetic Background: involves: 129S1/Sv * FVB/N

 MP:0009433 polyovular ovarian follicle "an ovarian follicle containing more than one oocyte (ovum)" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ptgs2tm2.1(Ptgs1)Fun/Ptgs2tm2.1(Ptgs1)Fun
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB

Allelic Composition: Dmrta1tm1.1Zark/Dmrta1+
Genetic Background: involves: 129S1/Sv * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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