ENSMUSG00000044017


Mus musculus

Features
Gene ID: ENSMUSG00000044017
  
Biological name :Adgrd1
  
Synonyms : Adgrd1 / Adhesion G-protein coupled receptor D1 / Q80T32
  
Possible biological names infered from orthology : Q6QNK2
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: G1.3
Gene start: 129096750
Gene end: 129204599
  
Corresponding Affymetrix probe sets: 10525989 (MoGene1.0st)   1455466_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000060307
Ensembl peptide - ENSMUSP00000121217
NCBI entrez gene - 243277     See in Manteia.
MGI - MGI:3041203
RefSeq - XM_006504308
RefSeq - NM_001081342
RefSeq - XM_006504307
RefSeq Peptide - NP_001334415
RefSeq Peptide - NP_001074811
swissprot - Q80T32
swissprot - B2RXV6
Ensembl - ENSMUSG00000044017
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adgrd1ENSDARG00000053344Danio rerio
 ADGRD1ENSGALG00000002557Gallus gallus
 ADGRD1ENSG00000111452Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Adgrl1 / Q80TR1 / Adhesion G protein-coupled receptor L1 / O94910*ENSMUSG0000001303323
Adgrl3 / Q80TS3 / Adhesion G protein-coupled receptor L3 / Q9HAR2*ENSMUSG0000003760522
Adgrl2 / Q8JZZ7 / Adhesion G protein-coupled receptor L2 / O95490*ENSMUSG0000002818422
Adgre1 / Q61549 / Mus musculus adhesion G protein-coupled receptor E1 (Adgre1), transcript variant 2, mRNA. / Q14246* / adhesion G protein-coupled receptor E1*ENSMUSG0000000473020
Adgre5 / adhesion G protein-coupled receptor E5 / P48960*ENSMUSG0000000288519
Adgrl4 / Q923X1 / Adhesion G protein-coupled receptor L4 / Q9HBW9*ENSMUSG0000003916718
Adgre4 / Q91ZE5 / Adhesion G protein-coupled receptor E4 ENSMUSG0000003291516


Protein motifs (from Interpro)
Interpro ID Name
 IPR000203  GPS motif
 IPR000832  GPCR, family 2, secretin-like
 IPR001759  Pentraxin-related
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR017981  GPCR, family 2-like
 IPR017983  GPCR, family 2, secretin-like, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007166 cell surface receptor signaling pathway IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000063 reduced bone density "decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315]
Show

Allelic Composition: Abcc2tm2b(KOMP)Wtsi/Abcc2tm2b(KOMP)Wtsi
Genetic Background: C57BL/6N-Abcc2tm2b(KOMP)Wtsi/H

 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
Show

Allelic Composition: Abcc2tm2b(KOMP)Wtsi/Abcc2tm2b(KOMP)Wtsi
Genetic Background: C57BL/6N-Abcc2tm2b(KOMP)Wtsi/H

 MP:0003345 decreased number of ribs "fewer than normal numbers of the pairs of bony structures that make up the body wall" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request]
Show

Allelic Composition: Abcc2tm2b(KOMP)Wtsi/Abcc2tm2b(KOMP)Wtsi
Genetic Background: C57BL/6N-Abcc2tm2b(KOMP)Wtsi/H

 MP:0010124 decreased bone mineral content "reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Abcc2tm2b(KOMP)Wtsi/Abcc2tm2b(KOMP)Wtsi
Genetic Background: C57BL/6N-Abcc2tm2b(KOMP)Wtsi/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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