ENSMUSG00000045994


Mus musculus

Features
Gene ID: ENSMUSG00000045994
  
Biological name :B3gat1
  
Synonyms : B3gat1 / Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 / Q9CW73
  
Possible biological names infered from orthology : beta-1,3-glucuronyltransferase 1 / Q9P2W7
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: A4
Gene start: 26733728
Gene end: 26763101
  
Corresponding Affymetrix probe sets: 10583929 (MoGene1.0st)   1425316_at (Mouse Genome 430 2.0 Array)   1425690_at (Mouse Genome 430 2.0 Array)   1425691_at (Mouse Genome 430 2.0 Array)   1454821_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000125700
Ensembl peptide - ENSMUSP00000110924
Ensembl peptide - ENSMUSP00000124067
Ensembl peptide - ENSMUSP00000124438
Ensembl peptide - ENSMUSP00000124752
NCBI entrez gene - 76898     See in Manteia.
MGI - MGI:1924148
RefSeq - XM_006510674
RefSeq - NM_001310766
RefSeq - NM_029792
RefSeq Peptide - NP_001297695
RefSeq Peptide - NP_084068
swissprot - Q9CW73
swissprot - A0A0R4J1Z6
Ensembl - ENSMUSG00000045994
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 b3gat1aENSDARG00000040547Danio rerio
 B3GAT1ENSGALG00000001611Gallus gallus
 B3GAT1ENSG00000109956Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
B3gat2 / P59270 / Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2 / Q9NPZ5* / beta-1,3-glucuronyltransferase 2*ENSMUSG0000002615642
B3gat3 / P58158 / Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 / O94766* / beta-1,3-glucuronyltransferase 3*ENSMUSG0000007164941


Protein motifs (from Interpro)
Interpro ID Name
 IPR005027  Glycosyl transferase, family 43
 IPR029044  Nucleotide-diphospho-sugar transferases


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IBA
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0030204 chondroitin sulfate metabolic process IBA
 biological_processGO:0050650 chondroitin sulfate proteoglycan biosynthetic process IBA
 cellular_componentGO:0000139 Golgi membrane IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane ISS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle ISO
 molecular_functionGO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity IDA
 molecular_functionGO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity IBA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
A tetrasaccharide linker sequence is required for GAG synthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001463 abnormal spatial learning "defects in the abilibity to navigate using behavioraly meaningful locations" [CFG:Center for Functional Genomics , Northwestern University]
Show

Allelic Composition: Cln3tm1Blda/Cln3tm1Blda
Genetic Background: B6.129-Cln3tm1Blda

 MP:0001473 reduced long term potentiation "less than the normal persistent robust synaptic response induced by synchronous stimulation of pre- and postsynaptic cells " [Principles of Neural Science:ISBN 0-8385-8034-3]
Show

Allelic Composition: Cln3tm1Blda/Cln3tm1Blda
Genetic Background: B6.129-Cln3tm1Blda

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000045994 B3gat1 / Q9CW73 / Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 / Q9P2W7* / beta-1,3-glucuronyltransferase 1*  / complex






 

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