ENSMUSG00000049076


Mus musculus

Features
Gene ID: ENSMUSG00000049076
  
Biological name :Acap2
  
Synonyms : Acap2 / ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 / Q6ZQK5
  
Possible biological names infered from orthology : Q15057
  
Species: Mus musculus
  
Chr. number: 16
Strand: -1
Band: B2
Gene start: 31092412
Gene end: 31201245
  
Corresponding Affymetrix probe sets: 10438980 (MoGene1.0st)   1433561_at (Mouse Genome 430 2.0 Array)   1441669_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000061501
Ensembl peptide - ENSMUSP00000154852
Ensembl peptide - ENSMUSP00000154938
Ensembl peptide - ENSMUSP00000154983
NCBI entrez gene - 78618     See in Manteia.
MGI - MGI:1925868
RefSeq - XM_017317164
RefSeq - NM_030138
RefSeq - XM_006522749
RefSeq - XM_017317162
RefSeq - XM_017317163
RefSeq - XM_006522743
RefSeq - XM_006522744
RefSeq - XM_006522746
RefSeq - XM_006522747
RefSeq - XM_006522748
RefSeq Peptide - NP_084414
swissprot - Q6ZQK5
swissprot - D4AFX6
Ensembl - ENSMUSG00000049076
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 acap2ENSDARG00000060783Danio rerio
 si:ch211-168b3.1ENSDARG00000056478Danio rerio
 ACAP2ENSGALG00000007040Gallus gallus
 ACAP2ENSG00000114331Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Acap3 / ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 / Q96P50*ENSMUSG0000002903362
Acap1 / Q8K2H4 / ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 / Q15027*ENSMUSG0000000158850
Asap2 / Q7SIG6 / Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 / O43150* / ArfGAP with SH3 domain, ankyrin repeat and PH domain 2*ENSMUSG0000005263225
Asap1 / Q9QWY8 / Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 / Q9ULH1* / ArfGAP with SH3 domain, ankyrin repeat and PH domain 1*ENSMUSG0000002237724
Asap3 / Q5U464 / Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 / Q8TDY4* / ArfGAP with SH3 domain, ankyrin repeat and PH domain 3*ENSMUSG0000003699523
Agap3 / arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform b / Q96P47* / ArfGAP with GTPase domain, ankyrin repeat and PH domain 3*ENSMUSG0000002335321
Agap2 / Q3UHD9 / Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 / Q99490* / ArfGAP with GTPase domain, ankyrin repeat and PH domain 2*ENSMUSG0000002542220
Agap1 / Q8BXK8 / Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 / Q9UPQ3* / ArfGAP with GTPase domain, ankyrin repeat and PH domain 1*ENSMUSG0000005501320


Protein motifs (from Interpro)
Interpro ID Name
 IPR001164  Arf GTPase activating protein
 IPR001849  Pleckstrin homology domain
 IPR002110  Ankyrin repeat
 IPR011993  PH-like domain superfamily
 IPR020683  Ankyrin repeat-containing domain
 IPR027267  AH/BAR domain superfamily
 IPR036770  Ankyrin repeat-containing domain superfamily
 IPR037278  ARFGAP/RecO-like zinc finger


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030029 actin filament-based process ISO
 biological_processGO:0036010 protein localization to endosome ISS
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:1990090 cellular response to nerve growth factor stimulus ISS
 cellular_componentGO:0001726 ruffle ISO
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0010008 endosome membrane ISS
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0017137 Rab GTPase binding IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0080025 phosphatidylinositol-3,5-bisphosphate binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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