ENSG00000114331


Homo sapiens

Features
Gene ID: ENSG00000114331
  
Biological name :ACAP2
  
Synonyms : ACAP2 / ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 / Q15057
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: q29
Gene start: 195274736
Gene end: 195443078
  
Corresponding Affymetrix probe sets: 1552472_a_at (Human Genome U133 Plus 2.0 Array)   212476_at (Human Genome U133 Plus 2.0 Array)   212477_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000412338
Ensembl peptide - ENSP00000411336
Ensembl peptide - ENSP00000413388
Ensembl peptide - ENSP00000489156
Ensembl peptide - ENSP00000484209
Ensembl peptide - ENSP00000324287
Ensembl peptide - ENSP00000405262
NCBI entrez gene - 23527     See in Manteia.
OMIM - 607766
RefSeq - XM_017006049
RefSeq - XM_011512602
RefSeq - XM_011512603
RefSeq - XM_011512604
RefSeq - XM_011512605
RefSeq - XM_011512606
RefSeq - XM_017006046
RefSeq - XM_017006047
RefSeq - XM_017006048
RefSeq - NM_012287
RefSeq - XM_006713557
RefSeq Peptide - NP_036419
swissprot - A0A0U1RQT1
swissprot - F8WAU0
swissprot - H7C3K3
swissprot - H7C3Q8
swissprot - A0A087X1H5
swissprot - C9J8L1
swissprot - Q15057
Ensembl - ENSG00000114331
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 acap2ENSDARG00000060783Danio rerio
 si:ch211-168b3.1ENSDARG00000056478Danio rerio
 ACAP2ENSGALG00000007040Gallus gallus
 Acap2ENSMUSG00000049076Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ACAP3 / Q96P50 / ArfGAP with coiled-coil, ankyrin repeat and PH domains 3ENSG0000013158461
ACAP1 / Q15027 / ArfGAP with coiled-coil, ankyrin repeat and PH domains 1ENSG0000007281850
ASAP1 / Q9ULH1 / ArfGAP with SH3 domain, ankyrin repeat and PH domain 1ENSG0000015331724
ASAP3 / Q8TDY4 / ArfGAP with SH3 domain, ankyrin repeat and PH domain 3ENSG0000008828024
ASAP2 / O43150 / ArfGAP with SH3 domain, ankyrin repeat and PH domain 2ENSG0000015169324
AGAP3 / Q96P47 / ArfGAP with GTPase domain, ankyrin repeat and PH domain 3ENSG0000013361220
AGAP2 / Q99490 / ArfGAP with GTPase domain, ankyrin repeat and PH domain 2ENSG0000013543920
AGAP1 / Q9UPQ3 / ArfGAP with GTPase domain, ankyrin repeat and PH domain 1ENSG0000015798519
AGAP6 / Q5VW22 / ArfGAP with GTPase domain, ankyrin repeat and PH domain 6ENSG0000020414917
AGAP5 / A6NIR3 / ArfGAP with GTPase domain, ankyrin repeat and PH domain 5ENSG0000017265016
AGAP4 / Q96P64 / ArfGAP with GTPase domain, ankyrin repeat and PH domain 4ENSG0000018823416
AGAP9 / Q5VTM2 / ArfGAP with GTPase domain, ankyrin repeat and PH domain 9ENSG0000020417215


Protein motifs (from Interpro)
Interpro ID Name
 IPR001164  Arf GTPase activating protein
 IPR001849  Pleckstrin homology domain
 IPR002110  Ankyrin repeat
 IPR011993  PH-like domain superfamily
 IPR020683  Ankyrin repeat-containing domain
 IPR027267  AH/BAR domain superfamily
 IPR036770  Ankyrin repeat-containing domain superfamily
 IPR037278  ARFGAP/RecO-like zinc finger


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0036010 protein localization to endosome ISS
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:1990090 cellular response to nerve growth factor stimulus ISS
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0010008 endosome membrane ISS
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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