ENSG00000133612


Homo sapiens

Features
Gene ID: ENSG00000133612
  
Biological name :AGAP3
  
Synonyms : AGAP3 / ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 / Q96P47
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q36.1
Gene start: 151085831
Gene end: 151144436
  
Corresponding Affymetrix probe sets: 225789_at (Human Genome U133 Plus 2.0 Array)   231299_at (Human Genome U133 Plus 2.0 Array)   239026_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000418159
Ensembl peptide - ENSP00000418125
Ensembl peptide - ENSP00000418921
Ensembl peptide - ENSP00000480655
Ensembl peptide - ENSP00000419801
Ensembl peptide - ENSP00000335589
Ensembl peptide - ENSP00000380413
Ensembl peptide - ENSP00000417151
Ensembl peptide - ENSP00000417910
Ensembl peptide - ENSP00000418016
NCBI entrez gene - 116988     See in Manteia.
OMIM - 616813
RefSeq - XM_017011735
RefSeq - NM_001042535
RefSeq - NM_001281300
RefSeq - NM_001308304
RefSeq - NM_001308305
RefSeq - NM_031946
RefSeq - XM_005249943
RefSeq - XM_011515780
RefSeq - XM_017011732
RefSeq - XM_017011733
RefSeq - XM_017011734
RefSeq Peptide - NP_001268229
RefSeq Peptide - NP_001295233
RefSeq Peptide - NP_001295234
RefSeq Peptide - NP_114152
RefSeq Peptide - NP_001036000
swissprot - H7C4U6
swissprot - H7C5G0
swissprot - A0A090N7Y0
swissprot - Q96P47
swissprot - E7ESL9
swissprot - C9J975
swissprot - H0Y873
swissprot - H7C4F1
Ensembl - ENSG00000133612
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 agap3ENSDARG00000087822Danio rerio
 ENSGALG00000031276Gallus gallus
 ENSGALG00000043576Gallus gallus
 Agap3ENSMUSG00000023353Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AGAP1 / Q9UPQ3 / ArfGAP with GTPase domain, ankyrin repeat and PH domain 1ENSG0000015798567
AGAP2 / Q99490 / ArfGAP with GTPase domain, ankyrin repeat and PH domain 2ENSG0000013543950
AGAP5 / A6NIR3 / ArfGAP with GTPase domain, ankyrin repeat and PH domain 5ENSG0000017265036
AGAP6 / Q5VW22 / ArfGAP with GTPase domain, ankyrin repeat and PH domain 6ENSG0000020414936
AGAP4 / Q96P64 / ArfGAP with GTPase domain, ankyrin repeat and PH domain 4ENSG0000018823435
AGAP9 / Q5VTM2 / ArfGAP with GTPase domain, ankyrin repeat and PH domain 9ENSG0000020417233
ACAP3 / Q96P50 / ArfGAP with coiled-coil, ankyrin repeat and PH domains 3ENSG0000013158419
ASAP1 / Q9ULH1 / ArfGAP with SH3 domain, ankyrin repeat and PH domain 1ENSG0000015331718
ASAP2 / O43150 / ArfGAP with SH3 domain, ankyrin repeat and PH domain 2ENSG0000015169317
ASAP3 / Q8TDY4 / ArfGAP with SH3 domain, ankyrin repeat and PH domain 3ENSG0000008828017
ACAP2 / Q15057 / ArfGAP with coiled-coil, ankyrin repeat and PH domains 2ENSG0000011433117
ACAP1 / Q15027 / ArfGAP with coiled-coil, ankyrin repeat and PH domains 1ENSG0000007281816


Protein motifs (from Interpro)
Interpro ID Name
 IPR001164  Arf GTPase activating protein
 IPR001806  Small GTPase superfamily
 IPR001849  Pleckstrin homology domain
 IPR002110  Ankyrin repeat
 IPR011993  PH-like domain superfamily
 IPR020683  Ankyrin repeat-containing domain
 IPR020849  Small GTPase superfamily, Ras-type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR036770  Ankyrin repeat-containing domain superfamily
 IPR037278  ARFGAP/RecO-like zinc finger


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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