ENSG00000157985


Homo sapiens

Features
Gene ID: ENSG00000157985
  
Biological name :AGAP1
  
Synonyms : AGAP1 / ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 / Q9UPQ3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q37.2
Gene start: 235494089
Gene end: 236131800
  
Corresponding Affymetrix probe sets: 204066_s_at (Human Genome U133 Plus 2.0 Array)   228240_at (Human Genome U133 Plus 2.0 Array)   235968_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000393838
Ensembl peptide - ENSP00000387174
Ensembl peptide - ENSP00000403482
Ensembl peptide - ENSP00000489496
Ensembl peptide - ENSP00000484463
Ensembl peptide - ENSP00000483085
Ensembl peptide - ENSP00000411824
Ensembl peptide - ENSP00000307634
Ensembl peptide - ENSP00000338378
Ensembl peptide - ENSP00000385492
Ensembl peptide - ENSP00000386897
NCBI entrez gene - 116987     See in Manteia.
OMIM - 608651
RefSeq - XM_017003282
RefSeq - NM_001037131
RefSeq - NM_001244888
RefSeq - NM_014914
RefSeq - XM_005246059
RefSeq - XM_006712234
RefSeq - XM_006712235
RefSeq - XM_006712237
RefSeq - XM_006712239
RefSeq - XM_011510547
RefSeq - XM_011510548
RefSeq - XM_011510549
RefSeq Peptide - NP_001231817
RefSeq Peptide - NP_055729
RefSeq Peptide - NP_001032208
swissprot - A0A0U1RRF1
swissprot - A0A087X1U1
swissprot - F5GXM9
swissprot - H7C0A7
swissprot - H7C211
swissprot - A0A087X044
swissprot - Q9UPQ3
swissprot - E7EUN2
swissprot - C9J8Z2
Ensembl - ENSG00000157985
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 agap1ENSDARG00000062123Danio rerio
 ENSGALG00000004045Gallus gallus
 Agap1ENSMUSG00000055013Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AGAP3 / Q96P47 / ArfGAP with GTPase domain, ankyrin repeat and PH domain 3ENSG0000013361271
AGAP2 / Q99490 / ArfGAP with GTPase domain, ankyrin repeat and PH domain 2ENSG0000013543953
AGAP5 / A6NIR3 / ArfGAP with GTPase domain, ankyrin repeat and PH domain 5ENSG0000017265052
AGAP6 / Q5VW22 / ArfGAP with GTPase domain, ankyrin repeat and PH domain 6ENSG0000020414951
AGAP4 / Q96P64 / ArfGAP with GTPase domain, ankyrin repeat and PH domain 4ENSG0000018823450
AGAP9 / Q5VTM2 / ArfGAP with GTPase domain, ankyrin repeat and PH domain 9ENSG0000020417247
ACAP3 / Q96P50 / ArfGAP with coiled-coil, ankyrin repeat and PH domains 3ENSG0000013158419
ASAP1 / Q9ULH1 / ArfGAP with SH3 domain, ankyrin repeat and PH domain 1ENSG0000015331718
ASAP2 / O43150 / ArfGAP with SH3 domain, ankyrin repeat and PH domain 2ENSG0000015169317
ACAP1 / Q15027 / ArfGAP with coiled-coil, ankyrin repeat and PH domains 1ENSG0000007281817
ASAP3 / Q8TDY4 / ArfGAP with SH3 domain, ankyrin repeat and PH domain 3ENSG0000008828017
ACAP2 / Q15057 / ArfGAP with coiled-coil, ankyrin repeat and PH domains 2ENSG0000011433117


Protein motifs (from Interpro)
Interpro ID Name
 IPR001164  Arf GTPase activating protein
 IPR001806  Small GTPase superfamily
 IPR001849  Pleckstrin homology domain
 IPR002110  Ankyrin repeat
 IPR011993  PH-like domain superfamily
 IPR020683  Ankyrin repeat-containing domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR036770  Ankyrin repeat-containing domain superfamily
 IPR037278  ARFGAP/RecO-like zinc finger


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0005543 phospholipid binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr