ENSG00000088280


Homo sapiens

Features
Gene ID: ENSG00000088280
  
Biological name :ASAP3
  
Synonyms : ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 / ASAP3 / Q8TDY4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p36.12
Gene start: 23428563
Gene end: 23484568
  
Corresponding Affymetrix probe sets: 219103_at (Human Genome U133 Plus 2.0 Array)   222236_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000436150
Ensembl peptide - ENSP00000435858
Ensembl peptide - ENSP00000436439
Ensembl peptide - ENSP00000483740
Ensembl peptide - ENSP00000476400
Ensembl peptide - ENSP00000338769
Ensembl peptide - ENSP00000408826
Ensembl peptide - ENSP00000434897
Ensembl peptide - ENSP00000435394
NCBI entrez gene - 55616     See in Manteia.
OMIM - 616594
RefSeq - XM_017001689
RefSeq - NM_001143778
RefSeq - NM_017707
RefSeq - XM_011541755
RefSeq - XM_017001685
RefSeq - XM_017001686
RefSeq - XM_017001687
RefSeq - XM_017001688
RefSeq Peptide - NP_001137250
RefSeq Peptide - NP_060177
swissprot - Q8TDY4
swissprot - E9PS98
swissprot - A0A087X0Y5
swissprot - H0YE36
swissprot - H0YEB0
swissprot - H0YER8
swissprot - V9GY49
swissprot - A0A024RAB1
Ensembl - ENSG00000088280
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 asap3ENSDARG00000021896Danio rerio
 ASAP3ENSGALG00000036949Gallus gallus
 Asap3ENSMUSG00000036995Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ASAP2 / O43150 / ArfGAP with SH3 domain, ankyrin repeat and PH domain 2ENSG0000015169347
ASAP1 / Q9ULH1 / ArfGAP with SH3 domain, ankyrin repeat and PH domain 1ENSG0000015331747
ACAP2 / Q15057 / ArfGAP with coiled-coil, ankyrin repeat and PH domains 2ENSG0000011433121
ACAP3 / Q96P50 / ArfGAP with coiled-coil, ankyrin repeat and PH domains 3ENSG0000013158421
ACAP1 / Q15027 / ArfGAP with coiled-coil, ankyrin repeat and PH domains 1ENSG0000007281819
AGAP3 / Q96P47 / ArfGAP with GTPase domain, ankyrin repeat and PH domain 3ENSG0000013361217
AGAP2 / Q99490 / ArfGAP with GTPase domain, ankyrin repeat and PH domain 2ENSG0000013543917
AGAP1 / Q9UPQ3 / ArfGAP with GTPase domain, ankyrin repeat and PH domain 1ENSG0000015798516
AGAP5 / A6NIR3 / ArfGAP with GTPase domain, ankyrin repeat and PH domain 5ENSG0000017265013
AGAP6 / Q5VW22 / ArfGAP with GTPase domain, ankyrin repeat and PH domain 6ENSG0000020414913
AGAP4 / Q96P64 / ArfGAP with GTPase domain, ankyrin repeat and PH domain 4ENSG0000018823413
AGAP9 / Q5VTM2 / ArfGAP with GTPase domain, ankyrin repeat and PH domain 9ENSG0000020417211


Protein motifs (from Interpro)
Interpro ID Name
 IPR001164  Arf GTPase activating protein
 IPR001849  Pleckstrin homology domain
 IPR002110  Ankyrin repeat
 IPR011993  PH-like domain superfamily
 IPR020683  Ankyrin repeat-containing domain
 IPR027267  AH/BAR domain superfamily
 IPR028775  Arf GTPase activating protein, ASAP3
 IPR036770  Ankyrin repeat-containing domain superfamily
 IPR037278  ARFGAP/RecO-like zinc finger


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016477 cell migration IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0051492 regulation of stress fiber assembly IMP
 cellular_componentGO:0001726 ruffle IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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