ENSMUSG00000055523


Mus musculus

Features
Gene ID: ENSMUSG00000055523
  
Biological name :Gucy2g
  
Synonyms : Guanylate cyclase 2G / Gucy2g / Q6TL19
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 19
Strand: -1
Band: D2
Gene start: 55198297
Gene end: 55241236
  
Corresponding Affymetrix probe sets: 10468562 (MoGene1.0st)   1430336_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000068253
NCBI entrez gene - 73707     See in Manteia.
MGI - MGI:106025
RefSeq - NM_001081076
RefSeq - XM_017318299
RefSeq Peptide - NP_001074545
swissprot - Q6TL19
Ensembl - ENSMUSG00000055523
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gucy2gENSDARG00000076776Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Npr1 / P18293 / natriuretic peptide receptor 1 / P16066*ENSMUSG0000002793131
Gucy2dENSMUSG0000007400330
Gucy2f / Q5SDA5 / Retinal guanylyl cyclase 2 / P51841* / guanylate cyclase 2F, retinal*ENSMUSG0000004228230
Npr2 / Q6VVW5 / natriuretic peptide receptor 2 / P20594*ENSMUSG0000002846930
Gucy2e / P52785 / Guanylyl cyclase GC-E / GUCY2D* / Q02846* / guanylate cyclase 2D, retinal*ENSMUSG0000002089029
Gucy2c / Q3UWA6 / Heat-stable enterotoxin receptor / P25092* / guanylate cyclase 2C*ENSMUSG0000004263825
Gucy1b2ENSMUSG0000002193315
Q9ERL9 / Gucy1a1 / guanylate cyclase 1, soluble, alpha 1 / Q02108* / guanylate cyclase 1 soluble subunit alpha 1*ENSMUSG0000003391013
Gucy1a2 / guanylate cyclase 1 soluble subunit alpha 2 / P33402*ENSMUSG0000004162413
O54865 / Gucy1b1 / guanylate cyclase 1, soluble, beta 1 / Q02153* / guanylate cyclase 1 soluble subunit beta 1*ENSMUSG0000002800512


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001054  Adenylyl cyclase class-3/4/guanylyl cyclase
 IPR001170  Adenylyl cyclase class-4/guanylyl cyclase
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR001828  Receptor, ligand binding region
 IPR011009  Protein kinase-like domain superfamily
 IPR018297  Adenylyl cyclase class-4/guanylyl cyclase, conserved site
 IPR028082  Periplasmic binding protein-like I
 IPR029787  Nucleotide cyclase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006182 cGMP biosynthetic process IDA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0009190 cyclic nucleotide biosynthetic process IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 cellular_componentGO:0008074 guanylate cyclase complex, soluble IBA
 cellular_componentGO:0009897 external side of plasma membrane IDA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004383 guanylate cyclase activity IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016849 phosphorus-oxygen lyase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0004042 decreased susceptibility to kidney reperfusion injury "a diminished likelihood or extent of damage to the kidney when the blood supply is restored after a period of ischemia" [brs:Beverly Richards-Smith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Alpltm1(cre)Nagy/Alpl+,Dicer1tm1.1Mnn/Dicer1tm1.2Mnn
Genetic Background: involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr