ENSMUSG00000056216


Mus musculus

Features
Gene ID: ENSMUSG00000056216
  
Biological name :Cebpg
  
Synonyms : CCAAT/enhancer-binding protein gamma / Cebpg / P53568
  
Possible biological names infered from orthology : P53567
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: B2
Gene start: 35046422
Gene end: 35056573
  
Corresponding Affymetrix probe sets: 10562416 (MoGene1.0st)   1425261_at (Mouse Genome 430 2.0 Array)   1425262_at (Mouse Genome 430 2.0 Array)   1451639_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000064963
Ensembl peptide - ENSMUSP00000118588
NCBI entrez gene - 12611     See in Manteia.
MGI - MGI:104982
RefSeq - NM_009884
RefSeq Peptide - NP_034014
swissprot - P53568
swissprot - Q54AJ1
Ensembl - ENSMUSG00000056216
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cebpgENSDARG00000036073Danio rerio
 CEBPGENSGALG00000032365Gallus gallus
 CEBPGENSG00000153879Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cebpb / P28033 / CCAAT/enhancer-binding protein beta / P17676*ENSMUSG0000005650133
Cebpe / Q6PZD9 / CCAAT/enhancer-binding protein epsilon / Q15744*ENSMUSG0000005243530
Cebpa / P53566 / CCAAT/enhancer-binding protein alpha / P49715*ENSMUSG0000003495729
Cebpd / Q00322 / CCAAT/enhancer-binding protein delta / P49716*ENSMUSG0000007163727


Protein motifs (from Interpro)
Interpro ID Name
 IPR004827  Basic-leucine zipper domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001889 liver development ISS
 biological_processGO:0006337 nucleosome disassembly TAS
 biological_processGO:0006338 chromatin remodeling TAS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II ISO
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006955 immune response IDA
 biological_processGO:0016071 mRNA metabolic process IMP
 biological_processGO:0030183 B cell differentiation IEP
 biological_processGO:0042267 natural killer cell mediated cytotoxicity IMP
 biological_processGO:0043353 enucleate erythrocyte differentiation IMP
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity IDA
 biological_processGO:0045078 positive regulation of interferon-gamma biosynthetic process IMP
 biological_processGO:0045739 positive regulation of DNA repair ISS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm ISO
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding ISO
 molecular_functionGO:0003677 DNA binding ISO
 molecular_functionGO:0003690 double-stranded DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding ISS
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0043565 sequence-specific DNA binding ISS
 molecular_functionGO:0044377 RNA polymerase II proximal promoter sequence-specific DNA binding, bending IEA
 molecular_functionGO:0046982 protein heterodimerization activity ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001183 overexpanded alveoli "expanded volume of the saclike terminal dilation of the respiratory bronchioles" [J:66345]
Show

Allelic Composition: Apobtm5Sgy/Apobtm5Sgy
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0005070 defective NK cell cytolysis "impaired ability of these cells to destroy or dissolve targeted cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:6213]
Show

Allelic Composition: Apobtm5Sgy/Apobtm5Sgy
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0010766 abnormal NK cell physiology "any functional anomaly of a lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors, and also regulate immune responses via cytokine release and direct contact with other cells" [GOC:add, ISBN:0781735149, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:15771571]
Show

Allelic Composition: Apobtm5Sgy/Apobtm5Sgy
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0011088 partial neonatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Apobtm5Sgy/Apobtm5Sgy
Genetic Background: involves: 129S4/SvJae * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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