Manteia

ENSMUSG00000060147

Mus musculus

Features

Gene ID:	ENSMUSG00000060147

Biological name :	Serpinb6a

Synonyms :	Q60854 / serine (or cysteine) peptidase inhibitor, clade B, member 6a / Serpinb6a

Possible biological names infered from orthology :	P35237 / SERPINB6 / serpin family B member 6

Species:	Mus musculus

Chr. number:	13
Strand:	-1
Band:	A3.3
Gene start:	33917918
Gene end:	34002794

Corresponding Affymetrix probe sets:	10408600 (MoGene1.0st) 1450138_a_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000126287 Ensembl peptide - ENSMUSP00000132433 Ensembl peptide - ENSMUSP00000131900 Ensembl peptide - ENSMUSP00000131115 Ensembl peptide - ENSMUSP00000130356 Ensembl peptide - ENSMUSP00000128267 Ensembl peptide - ENSMUSP00000127768 Ensembl peptide - ENSMUSP00000127224 Ensembl peptide - ENSMUSP00000126450 Ensembl peptide - ENSMUSP00000017188 Ensembl peptide - ENSMUSP00000041016 Ensembl peptide - ENSMUSP00000075848 Ensembl peptide - ENSMUSP00000126162 NCBI entrez gene - 20719 See in Manteia. MGI - MGI:103123 RefSeq - XM_011244301 RefSeq - NM_001164117 RefSeq - NM_001164118 RefSeq - NM_001243192 RefSeq - NM_009254 RefSeq - XM_006516623 RefSeq - XM_011244299 RefSeq - XM_011244300 RefSeq Peptide - NP_001230121 RefSeq Peptide - NP_033280 RefSeq Peptide - NP_001157589 RefSeq Peptide - NP_001157590 swissprot - E9Q6X2 swissprot - E9Q4R2 swissprot - E9Q3Y1 swissprot - E9Q108 swissprot - E9Q0P9 swissprot - E9PZQ9 swissprot - E9PYY0 swissprot - K7E6F1 swissprot - F8WIV2 swissprot - E9Q5Q5 swissprot - Q4FJQ6 swissprot - Q60854 Ensembl - ENSMUSG00000060147

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
serpinb14	ENSDARG00000091801	Danio rerio
serpinb1l1	ENSDARG00000095830	Danio rerio
serpinb1l3	ENSDARG00000014556	Danio rerio
serpinb1l4	ENSDARG00000096888	Danio rerio
zgc:173729	ENSDARG00000057263	Danio rerio
SERPINB6L	ENSGALG00000012866	Gallus gallus
P35237	ENSG00000124570	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Serpinb6b / serine (or cysteine) peptidase inhibitor, clade B, member 6b / P35237* / SERPINB6* / serpin family B member 6*	ENSMUSG00000042842	76
Serpinb6c / serine (or cysteine) peptidase inhibitor, clade B, member 6c / P35237* / SERPINB6* / serpin family B member 6*	ENSMUSG00000052180	74
Serpinb6e / P35237* / SERPINB6* / serpin family B member 6*	ENSMUSG00000069248	64
Serpinb6d / serine (or cysteine) peptidase inhibitor, clade B, member 6d / P35237* / SERPINB6* / serpin family B member 6*	ENSMUSG00000047889	62
O08800 / Serpinb8 / Serpin B8 / P50452* / serpin family B member 8*	ENSMUSG00000026315	57
Serpinb9f / P50453* / SERPINB9* / serpin family B member 9*	ENSMUSG00000038327	53
Serpinb9e / serine (or cysteine) peptidase inhibitor, clade B, member 9e / P50453* / SERPINB9* / serpin family B member 9*	ENSMUSG00000062342	53
Serpinb9g / serine (or cysteine) peptidase inhibitor, clade B, member 9g / P50453* / SERPINB9* / serpin family B member 9*	ENSMUSG00000057726	53
Gm11397 / P50453* / SERPINB9* / serpin family B member 9*	ENSMUSG00000071452	52
Serpinb9d / serine (or cysteine) peptidase inhibitor, clade B, member 9d / P50453* / SERPINB9* / serpin family B member 9*	ENSMUSG00000054266	52
Serpinb9 / serine (or cysteine) peptidase inhibitor, clade B, member 9 / P50453* / serpin family B member 9*	ENSMUSG00000045827	52
Serpinb9b / serine (or cysteine) peptidase inhibitor, clade B, member 9b / P50453* / SERPINB9* / serpin family B member 9*	ENSMUSG00000021403	51
Serpinb9c / serine (or cysteine) peptidase inhibitor, clade B, member 9c / P50453* / SERPINB9* / serpin family B member 9*	ENSMUSG00000021404	49
Q9D154 / Serpinb1a / serine (or cysteine) peptidase inhibitor, clade B, member 1a / P30740* / SERPINB1* / serpin family B member 1*	ENSMUSG00000044734	47
Q8VHP7 / Serpinb1b / serine (or cysteine) peptidase inhibitor, clade B, member 1b / P30740* / SERPINB1* / serpin family B member 1*	ENSMUSG00000051029	46
Q5SV42 / Serpinb1c / serine (or cysteine) peptidase inhibitor, clade B, member 1c / P30740* / SERPINB1* / serpin family B member 1*	ENSMUSG00000079049	44
P12388 / Serpinb2 / serine (or cysteine) peptidase inhibitor, clade B, member 2 / P05120* / serpin family B member 2*	ENSMUSG00000062345	43
Serpinb3a / P48594* / P29508* / SERPINB3* / SERPINB4* / serpin family B member 3* / serpin family B member 4*	ENSMUSG00000044594	42
Serpinb3b / serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3B / P29508* / P48594* / SERPINB3* / SERPINB4* / serpin family B member 3* / serpin family B member 4*	ENSMUSG00000073602	42
Serpinb3c / P48594* / P29508* / SERPINB3* / SERPINB4* / serpin family B member 3* / serpin family B member 4*	ENSMUSG00000073601	41

Protein motifs (from Interpro)

Interpro ID	Name
IPR000215	Serpin family
IPR023795	Serpin, conserved site
IPR023796	Serpin domain
IPR036186	Serpin superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0007605	sensory perception of sound	ISO
biological_process	GO:0008406	gonad development	NAS
biological_process	GO:0010466	negative regulation of peptidase activity	IEA
biological_process	GO:0010951	negative regulation of endopeptidase activity	NAS
biological_process	GO:0071470	cellular response to osmotic stress	ISO
cellular_component	GO:0005576	extracellular region	ISO
cellular_component	GO:0005615	extracellular space	IBA
cellular_component	GO:0005622	intracellular	IDA
cellular_component	GO:0005737	cytoplasm	IEA
cellular_component	GO:0097180	serine protease inhibitor complex	ISO
molecular_function	GO:0002020	protease binding	ISO
molecular_function	GO:0004867	serine-type endopeptidase inhibitor activity	NAS
molecular_function	GO:0005515	protein binding	IPI
molecular_function	GO:0030414	peptidase inhibitor activity	IEA

Pathways (from Reactome)

Pathway description

Neutrophil degranulation

Dissolution of Fibrin Clot

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0002169	no phenotype detected	"normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Gja1^tm1Kwi/Gja1^{tm5(cre/ERT)Kwi} Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr