ENSMUSG00000061080


Mus musculus

Features
Gene ID: ENSMUSG00000061080
  
Biological name :Lsamp
  
Synonyms : Lsamp / Mus musculus limbic system-associated membrane protein (Lsamp), transcript variant 2, mRNA. / Q8BLK3
  
Possible biological names infered from orthology : limbic system-associated membrane protein / Q13449
  
Species: Mus musculus
  
Chr. number: 16
Strand: 1
Band: B4
Gene start: 39984361
Gene end: 42181679
  
Corresponding Affymetrix probe sets: 10435748 (MoGene1.0st)   10435752 (MoGene1.0st)   1435895_at (Mouse Genome 430 2.0 Array)   1455636_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000115823
Ensembl peptide - ENSMUSP00000140114
Ensembl peptide - ENSMUSP00000139814
Ensembl peptide - ENSMUSP00000139667
Ensembl peptide - ENSMUSP00000139655
Ensembl peptide - ENSMUSP00000139576
Ensembl peptide - ENSMUSP00000139449
Ensembl peptide - ENSMUSP00000077913
Ensembl peptide - ENSMUSP00000097349
NCBI entrez gene - 268890     See in Manteia.
MGI - MGI:1261760
RefSeq - XM_006522202
RefSeq - NM_001347236
RefSeq - NM_175548
RefSeq - XM_006522201
RefSeq Peptide - NP_001334165
RefSeq Peptide - NP_780757
swissprot - A0A087WPK6
swissprot - Q8BLK3
swissprot - A0A087WQA7
swissprot - Q3TYE5
swissprot - A0A087WP80
swissprot - A0A087WP70
swissprot - A0A087WNQ5
swissprot - A0A087WP06
swissprot - F6SB80
Ensembl - ENSMUSG00000061080
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LSAMPENSDARG00000103069Danio rerio
 LSAMPENSGALG00000040620Gallus gallus
 LSAMPENSG00000185565Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Negr1 / Q80Z24 / neuronal growth regulator 1 / Q7Z3B1*ENSMUSG0000004003751
Opcml / opioid binding protein/cell adhesion molecule-like / Q14982*ENSMUSG0000006225749
Ntm / Q99PJ0 / Mus musculus neurotrimin (Ntm), transcript variant 7, mRNA. / Q9P121* / neurotrimin*ENSMUSG0000005997448
Iglon5 / Q8HW98 / IgLON family member 5 / A6NGN9*ENSMUSG0000001336744


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0035641 locomotory exploration behavior IMP
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031225 anchored component of membrane IEA


Pathways (from Reactome)
Pathway description
Post-translational modification: synthesis of GPI-anchored proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,E4f1tm1Pisc/E4f1tm1.1Llca,Polr2atm1(cre/ERT2)Bbd/Polr2a+
Genetic Background: involves: 129/Sv * 129S4/SvJae * C57BL/6 * SJL

 MP:0001364 decreased anxiety-related response "when compared to controls, subjects exhibit fewer responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:86626, J:85438, J:64043]
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,E4f1tm1Pisc/E4f1tm1.1Llca,Polr2atm1(cre/ERT2)Bbd/Polr2a+
Genetic Background: involves: 129/Sv * 129S4/SvJae * C57BL/6 * SJL

 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,E4f1tm1Pisc/E4f1tm1.1Llca,Polr2atm1(cre/ERT2)Bbd/Polr2a+
Genetic Background: involves: 129/Sv * 129S4/SvJae * C57BL/6 * SJL

 MP:0001415 increased exploration in new environment "greater amount of time spent investigating new location" [J:28825]
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Allelic Composition: Cacna2d2du-2J/Cacna2d2du-2J
Genetic Background: involves: C57BLKS/J-Cacna2d2du-2J/LetJ

 MP:0001440 abnormal grooming behavior "defects in the standard of behavior of cleaning and/or keeping outward appearance tidy (self, mate or offspring)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,E4f1tm1Pisc/E4f1tm1.1Llca,Polr2atm1(cre/ERT2)Bbd/Polr2a+
Genetic Background: involves: 129/Sv * 129S4/SvJae * C57BL/6 * SJL

 MP:0001522 impaired swimming "reduced ability or inability to swim" [J:45446, J:39081]
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,E4f1tm1Pisc/E4f1tm1.1Llca,Polr2atm1(cre/ERT2)Bbd/Polr2a+
Genetic Background: involves: 129/Sv * 129S4/SvJae * C57BL/6 * SJL

 MP:0002557 abnormal social/conspecific interaction "deviation of the normal behavior of mice towards each other" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,E4f1tm1Pisc/E4f1tm1.1Llca,Polr2atm1(cre/ERT2)Bbd/Polr2a+
Genetic Background: involves: 129/Sv * 129S4/SvJae * C57BL/6 * SJL

 MP:0003862 decreased aggression towards males "when compared to controls, subjects exhibit less than normal level of domineering, assaultive posture and/or hostile physical action towards male mice " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,E4f1tm1Pisc/E4f1tm1.1Llca,Polr2atm1(cre/ERT2)Bbd/Polr2a+
Genetic Background: involves: 129/Sv * 129S4/SvJae * C57BL/6 * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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