ENSMUSG00000066568


Mus musculus

Features
Gene ID: ENSMUSG00000066568
  
Biological name :Lsm14a
  
Synonyms : A / Lsm14a / Q8K2F8
  
Possible biological names infered from orthology : LSM14A, mRNA processing body assembly factor / Q8ND56
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: B1
Gene start: 34344646
Gene end: 34393315
  
Corresponding Affymetrix probe sets: 10562382 (MoGene1.0st)   1428436_at (Mouse Genome 430 2.0 Array)   1428437_at (Mouse Genome 430 2.0 Array)   1428438_s_at (Mouse Genome 430 2.0 Array)   1457738_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000119461
Ensembl peptide - ENSMUSP00000118766
Ensembl peptide - ENSMUSP00000145807
Ensembl peptide - ENSMUSP00000145972
Ensembl peptide - ENSMUSP00000145883
Ensembl peptide - ENSMUSP00000082723
NCBI entrez gene - 67070     See in Manteia.
MGI - MGI:1914320
RefSeq - XM_017312254
RefSeq - NM_025948
RefSeq - XM_006540299
RefSeq - XM_011250678
RefSeq - XM_011250679
RefSeq - XM_011250680
RefSeq - XM_011250681
RefSeq Peptide - NP_080224
swissprot - A2BH69
swissprot - A0A0U1RPG3
swissprot - Q8K2F8
swissprot - A0A0U1RP90
swissprot - A0A0U1RP30
swissprot - F6X2V9
Ensembl - ENSMUSG00000066568
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lsm14aaENSDARG00000006600Danio rerio
 lsm14abENSDARG00000100553Danio rerio
 LSM14AENSGALG00000004935Gallus gallus
 LSM14AENSG00000257103Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
B / Lsm14b / Q8CGC4 / Q9BX40* / LSM family member 14B*ENSMUSG0000003910847


Protein motifs (from Interpro)
Interpro ID Name
 IPR010920  LSM domain superfamily
 IPR019050  FDF domain
 IPR025609  Lsm14-like, N-terminal
 IPR025761  FFD box
 IPR025762  DFDF domain
 IPR025768  TFG box


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0033962 cytoplasmic mRNA processing body assembly IEA
 biological_processGO:0039529 RIG-I signaling pathway IGI
 biological_processGO:0051607 defense response to virus IMP
 biological_processGO:0060340 positive regulation of type I interferon-mediated signaling pathway IDA
 cellular_componentGO:0000932 P-body ISO
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0010494 cytoplasmic stress granule ISS
 cellular_componentGO:0036464 cytoplasmic ribonucleoprotein granule IEA
 molecular_functionGO:0003690 double-stranded DNA binding IDA
 molecular_functionGO:0003725 double-stranded RNA binding IDA
 molecular_functionGO:0003727 single-stranded RNA binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Krit1tm1.1(KOMP)Vlcg/Krit1+
Genetic Background: C57BL/6N-Krit1tm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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