| MP:0000266 | abnormal cardiac morphology | "anomalies in the hollow, muscular organ that maintains the circulation of the blood" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: B2mtm1Unc/B2mtm1Unc,Tbptm1.1Ees/Tbptm1.1Ees
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
|
| MP:0000284 | double outlet right ventricle | "both the aorta and the pulmonary trunk originate from the right ventricle, usually in conjunction with a ventricular septal defect" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:67826] |
Show
Allelic Composition: B2mtm1Unc/B2mtm1Unc,Tbptm1.1Ees/Tbptm1.1Ees
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
|
| MP:0000542 | left-sided isomerism | "the relative symmetry of the organs of the thorax and abdomen as indicated by both atria displaying the morphology of the left atrium" [ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator] |
Show
Allelic Composition: B2mtm1Unc/B2mtm1Unc,Tbptm1.1Ees/Tbptm1.1Ees
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
|
| MP:0000598 | abnormal liver morphology | "malformation or absence of this bile-secreting exocrine gland, which is important for detoxification; for fat, carbohydrate, and protein metabolism; and for glycogen storage " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:23170] |
Show
Allelic Composition: B2mtm1Unc/B2mtm1Unc,Tbptm1.1Ees/Tbptm1.1Ees
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
|
| MP:0000644 | dextrocardia | "cardiac apex pointing to the right as opposed to the normal levocardia" [ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator] |
Show
Allelic Composition: B2mtm1Unc/B2mtm1Unc,Tbptm1.1Ees/Tbptm1.1Ees
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
|
| MP:0000932 | absent notochord | "missing axial fibrocellular cord in embryos around which develops the vertebral primordia" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:12622] |
Show
Allelic Composition: Lefty2tm1Hmd/Lefty2tm1Hmd
Genetic Background: involves: 129P2/OlaHsd * C57BL/6Cr
|
| MP:0001672 | abnormal embryogenesis/ development | "anomaly in the establishment of the characteristic configuration of the embryonic body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: B2mtm1Unc/B2mtm1Unc,Tbptm1.1Ees/Tbptm1.1Ees
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
Allelic Composition: Lefty2tm1Hmd/Lefty2tm1Hmd
Genetic Background: involves: 129P2/OlaHsd * C57BL/6Cr
|
| MP:0001675 | abnormal ectoderm development | "failure or abnormality in the formation of the ectoderm during gastrulation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Lefty2tm1Hmd/Lefty2tm1Hmd
Genetic Background: involves: 129P2/OlaHsd * C57BL/6Cr
|
| MP:0001706 | abnormal left-right axis patterning | "anomaly in the formation or development of the body or a specific organ of the body in relation to the left and right sides of the body or organ" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: B2mtm1Unc/B2mtm1Unc,Tbptm1.1Ees/Tbptm1.1Ees
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
|
| MP:0001718 | abnormal yolk sac | "malformed extraembryonic tissue which contributes to hematopoietic circulation" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:12623] |
Show
Allelic Composition: Lefty2tm1Hmd/Lefty2tm1Hmd
Genetic Background: involves: 129P2/OlaHsd * C57BL/6Cr
|
| MP:0001719 | absent vitelline blood vessels | "missing vasculature of the yolk sac" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:62571, J:12623] |
Show
Allelic Composition: Lefty2tm1Hmd/Lefty2tm1Hmd
Genetic Background: involves: 129P2/OlaHsd * C57BL/6Cr
|
| MP:0002084 | abnormal developmental patterning | "abnormal systematic arrangement of the developing body along an axis" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Lefty2tm1Hmd/Lefty2tm1Hmd
Genetic Background: involves: 129P2/OlaHsd * C57BL/6Cr
|
| MP:0002231 | abnormal primitive streak morphology | "anomaly in the midline ridge of the embryonic epiblast that later develops into mesoderm and endoderm" [The Atlas of Mouse Development:ISBN 0-12-402035-6, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Lefty2tm1Hmd/Lefty2tm1Hmd
Genetic Background: involves: 129P2/OlaHsd * C57BL/6Cr
|
| MP:0003284 | abnormal large intestine placement | "different location or arrangement of the large intestinal tract" [ncbi:Matthew Mailman, NCBI request] |
Show
Allelic Composition: B2mtm1Unc/B2mtm1Unc,Tbptm1.1Ees/Tbptm1.1Ees
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
|
| MP:0003342 | accessory spleen | "the splenic tissue is divided into equal masses; often related to situs inversus" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, ncbi:Matthew Mailman, NCBI request] |
Show
Allelic Composition: B2mtm1Unc/B2mtm1Unc,Tbptm1.1Ees/Tbptm1.1Ees
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
|
| MP:0003872 | absent right ventricle | "missing the lower right chamber of the heart" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
Show
Allelic Composition: B2mtm1Unc/B2mtm1Unc,Tbptm1.1Ees/Tbptm1.1Ees
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
|
| MP:0004110 | transposition of great arteries | "cardiovascular malformation in which the aorta arises from the right ventricle while the pulmonary artery arises from the left ventricle" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
Show
Allelic Composition: B2mtm1Unc/B2mtm1Unc,Tbptm1.1Ees/Tbptm1.1Ees
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
|
| MP:0006063 | abnormal inferior vena cava morphology | "structural malformation in the principal vein draining blood from the lower portion of the body" [smb:Susan M Bello, Mouse Genome Informatics Curator, Taber s Cyclopedic Medical Dictionary:19th edition: ISBN N 0-8036-0655-99] |
Show
Allelic Composition: B2mtm1Unc/B2mtm1Unc,Tbptm1.1Ees/Tbptm1.1Ees
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
|
| MP:0006123 | tricuspid valve atresia | "congenital closure of the tricuspid valve" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator] |
Show
Allelic Composition: B2mtm1Unc/B2mtm1Unc,Tbptm1.1Ees/Tbptm1.1Ees
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
|
| MP:0006386 | absent somites | "missing all somites" [MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Lefty2tm1Hmd/Lefty2tm1Hmd
Genetic Background: involves: 129P2/OlaHsd * C57BL/6Cr
|
| MP:0008461 | left atrial isomerism | "anomaly in the asymmetry of the cardiac atria such that atria on both the left and right side have the morphology normally seen on the left side of the body" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: B2mtm1Unc/B2mtm1Unc,Tbptm1.1Ees/Tbptm1.1Ees
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
|
| MP:0009331 | absent primitive node | "absence of the regional thickening of cells at the rostral tip of the vertebrate primitive streak through which gastrulating cells migrate anteriorally to form tissues in the future head and neck; this region organizes the formation of the three embryonic layers and establishes the longitudinal axis and the polarity of the embryo" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Lefty2tm1Hmd/Lefty2tm1Hmd
Genetic Background: involves: 129P2/OlaHsd * C57BL/6Cr
|
| MP:0009657 | failure of chorioallantoic fusion | "failure to initiate and/or complete the formation of a highly vascularized extra-embryonic fetal membrane by fusion of the chorion and allantois" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Lefty2tm1Hmd/Lefty2tm1Hmd
Genetic Background: involves: 129P2/OlaHsd * C57BL/6Cr
|
| MP:0010413 | complete atrioventricular septal defect | "a type of atrioventricular septal defect in which a single atrioventricular valve annulus, a common atrioventricular valve, and a defect of the inlet ventricular septum are observed; deficiency of the atrioventricular septum also results in the presence of a large primum atrial septal defect" [http://emedicine.medscape.com] |
Show
Allelic Composition: B2mtm1Unc/B2mtm1Unc,Tbptm1.1Ees/Tbptm1.1Ees
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
|
| MP:0010426 | abnormal heart and great artery attachment | "any anomaly in the in the position or pattern of the connection site of the heart to any of the great arteries, including the pulmonary artery and aorta" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: B2mtm1Unc/B2mtm1Unc,Tbptm1.1Ees/Tbptm1.1Ees
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
|
| MP:0010668 | abnormal hepatic portal vein morphology | "any structural anomaly of the wide short vein formed from the confluence of the superior mesenteric, inferior mesenteric and splenic veins, and then divides into the right and left branches which ramify with the liver; the hepatic portal vein carries venous blood from the GI tract, spleen and pancreas to the liver" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: B2mtm1Unc/B2mtm1Unc,Tbptm1.1Ees/Tbptm1.1Ees
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
|
| MP:0011086 | partial postnatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
Show
Allelic Composition: B2mtm1Unc/B2mtm1Unc,Tbptm1.1Ees/Tbptm1.1Ees
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
|
| MP:0011096 | complete embryonic lethality before somite formation | "death of all organisms of a given genotype in a population between the point of implantation and somite formation (Mus: E4.5 to less than E8)" [MGI:csmith] |
Show
Allelic Composition: Lefty2tm1Hmd/Lefty2tm1Hmd,Nodaltm1Rob/Nodal+
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6Cr
|
| MP:0011098 | complete embryonic lethality during organogenesis | "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith] |
Show
Allelic Composition: Lefty2tm1Hmd/Lefty2tm1Hmd
Genetic Background: involves: 129P2/OlaHsd * C57BL/6Cr
|
| MP:0011257 | abnormal head fold morphology | "any structural anomaly of the crescent-shaped, ventrally located fold of the embryonic disc at the future cephalic end of the developing embryo; it constitutes the first body fold, and initiates brain, foregut and heart development" [ISBN:0-683-40008-8, PMID:10791309] |
Show
Allelic Composition: Lefty2tm1Hmd/Lefty2tm1Hmd
Genetic Background: involves: 129P2/OlaHsd * C57BL/6Cr
|
| MP:0011388 | absent heart | "absence of the hollow, muscular organ that maintains the circulation of the blood" [MGI:smb] |
Show
Allelic Composition: Lefty2tm1Hmd/Lefty2tm1Hmd
Genetic Background: involves: 129P2/OlaHsd * C57BL/6Cr
|
