ENSMUSG00000069678


Mus musculus

Features
Gene ID: ENSMUSG00000069678
  
Biological name :Pcgf1
  
Synonyms : Pcgf1 / Polycomb group RING finger protein 1 / Q8R023
  
Possible biological names infered from orthology : polycomb group ring finger 1 / Q9BSM1
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: C3
Gene start: 83077869
Gene end: 83080855
  
Corresponding Affymetrix probe sets: 10539310 (MoGene1.0st)   1427956_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000135268
Ensembl peptide - ENSMUSP00000135291
Ensembl peptide - ENSMUSP00000135664
Ensembl peptide - ENSMUSP00000135882
Ensembl peptide - ENSMUSP00000090277
Ensembl peptide - ENSMUSP00000130614
NCBI entrez gene - 69837     See in Manteia.
MGI - MGI:1917087
RefSeq - NM_197992
RefSeq Peptide - NP_932109
swissprot - Q8R023
swissprot - A0A0R4J141
swissprot - H3BK63
swissprot - H3BK85
swissprot - H3BL61
swissprot - H3BLR0
Ensembl - ENSMUSG00000069678
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pcgf1ENSDARG00000001249Danio rerio
 PCGF1ENSG00000115289Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pcgf3 / Q8BTQ0 / Polycomb group RING finger protein 3 / Q3KNV8* / polycomb group ring finger 3*ENSMUSG0000003362338
Pcgf6 / Q99NA9 / Polycomb group RING finger protein 6 / Q9BYE7* / polycomb group ring finger 6*ENSMUSG0000002505035
Pcgf2 / P23798 / Polycomb group RING finger protein 2 / P35227* / polycomb group ring finger 2*ENSMUSG0000001853734
Bmi1 / P25916 / Polycomb complex protein BMI-1 / P35226* / COMMD3-BMI1* / COMMD3-BMI1 readthrough* / BMI1 proto-oncogene, polycomb ring finger*ENSMUSG0000002673934
Pcgf5 / Q3UK78 / Polycomb group RING finger protein 5 / Q86SE9* / polycomb group ring finger 5*ENSMUSG0000002480532


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site
 IPR029071  Ubiquitin-like domain superfamily
 IPR032443  RAWUL domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0035518 histone H2A monoubiquitination IEA
 biological_processGO:0036353 histone H2A-K119 monoubiquitination IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0031519 PcG protein complex IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Nphp1tm1.1(KOMP)Vlcg/Nphp1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Nphp1tm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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