ENSMUSG00000074170


Mus musculus

Features
Gene ID: ENSMUSG00000074170
  
Biological name :Plekhf1
  
Synonyms : Pleckstrin homology domain-containing family F member 1 / Plekhf1 / Q3TB82
  
Possible biological names infered from orthology : pleckstrin homology and FYVE domain containing 1 / Q96S99
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: B3
Gene start: 38216972
Gene end: 38228016
  
Corresponding Affymetrix probe sets: 10562576 (MoGene1.0st)   1424671_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000096113
NCBI entrez gene - 72287     See in Manteia.
MGI - MGI:1919537
RefSeq - NM_024413
RefSeq Peptide - NP_077724
swissprot - Q3TB82
Ensembl - ENSMUSG00000074170
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 plekhf1ENSDARG00000102435Danio rerio
 PLEKHF1ENSGALG00000004474Gallus gallus
 Q96S99ENSG00000166289Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q91WB4 / Plekhf2 / Pleckstrin homology domain-containing family F member 2 / Q9H8W4* / pleckstrin homology and FYVE domain containing 2*ENSMUSG0000004996948
Fgd6 / Q69ZL1 / FYVE, RhoGEF and PH domain-containing protein 6 / Q6ZV73* / FYVE, RhoGEF and PH domain containing 6*ENSMUSG0000002002130
Fgd5 / FYVE, RhoGEF and PH domain containing 5 / Q6ZNL6*ENSMUSG0000003403727
Fgd1 / P52734 / FYVE, RhoGEF and PH domain-containing protein 1 / P98174* / FYVE, RhoGEF and PH domain containing 1*ENSMUSG0000002526525
Fgd4 / Q91ZT5 / FYVE, RhoGEF and PH domain-containing protein 4 / Q96M96* / FYVE, RhoGEF and PH domain containing 4*ENSMUSG0000002278824
Fgd2 / Q8BY35 / FYVE, RhoGEF and PH domain-containing protein 2 / Q7Z6J4* / FYVE, RhoGEF and PH domain containing 2*ENSMUSG0000002401324
Fgd3 / FYVE, RhoGEF and PH domain containing 3 / Q5JSP0*ENSMUSG0000003794622


Protein motifs (from Interpro)
Interpro ID Name
 IPR000306  FYVE zinc finger
 IPR001849  Pleckstrin homology domain
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR011993  PH-like domain superfamily
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017455  Zinc finger, FYVE-related


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007032 endosome organization IEA
 biological_processGO:0010508 positive regulation of autophagy IEA
 biological_processGO:0016050 vesicle organization IEA
 biological_processGO:0046902 regulation of mitochondrial membrane permeability ISO
 biological_processGO:0072659 protein localization to plasma membrane IEA
 biological_processGO:2001244 positive regulation of intrinsic apoptotic signaling pathway IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005764 lysosome ISO
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0010314 phosphatidylinositol-5-phosphate binding IEA
 molecular_functionGO:0032266 phosphatidylinositol-3-phosphate binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070273 phosphatidylinositol-4-phosphate binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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