ENSMUSG00000074643


Mus musculus

Features
Gene ID: ENSMUSG00000074643
  
Biological name :Cpne1
  
Synonyms : Copine-1 / Cpne1 / Q8C166
  
Possible biological names infered from orthology : Q99829
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: H1
Gene start: 156071842
Gene end: 156111965
  
Corresponding Affymetrix probe sets: 10488982 (MoGene1.0st)   1433439_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000118140
Ensembl peptide - ENSMUSP00000139230
Ensembl peptide - ENSMUSP00000139035
Ensembl peptide - ENSMUSP00000138888
Ensembl peptide - ENSMUSP00000122994
Ensembl peptide - ENSMUSP00000122644
Ensembl peptide - ENSMUSP00000121998
Ensembl peptide - ENSMUSP00000121299
Ensembl peptide - ENSMUSP00000078292
Ensembl peptide - ENSMUSP00000105236
Ensembl peptide - ENSMUSP00000105237
Ensembl peptide - ENSMUSP00000115167
Ensembl peptide - ENSMUSP00000116982
NCBI entrez gene - 266692     See in Manteia.
MGI - MGI:2386621
RefSeq - NM_170588
RefSeq - NM_170590
RefSeq Peptide - NP_733469
RefSeq Peptide - NP_733467
swissprot - B7ZCP4
swissprot - A3KGK7
swissprot - F6R587
swissprot - Q8C166
swissprot - V9GWY2
swissprot - V9GX86
swissprot - E9Q806
swissprot - V9GXM6
swissprot - B7ZCP8
swissprot - B7ZCP7
swissprot - B7ZCP6
swissprot - B7ZCP5
Ensembl - ENSMUSG00000074643
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cpne1ENSDARG00000075536Danio rerio
 CPNE1ENSGALG00000040856Gallus gallus
 CPNE1ENSG00000214078Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cpne3 / Q8BT60 / Copine-3 / O75131*ENSMUSG0000002822866
Cpne2 / P59108 / Copine-2 / Q96FN4*ENSMUSG0000003436157
Cpne4 / Q8BLR2 / Copine-4 / Q96A23*ENSMUSG0000003256451
Cpne7 / Q0VE82 / Copine-7 / Q9UBL6*ENSMUSG0000003479651
Cpne6 / Q9Z140 / Copine-6 / O95741*ENSMUSG0000002221250
Cpne8 / Q9DC53 / Mus musculus copine VIII (Cpne8), transcript variant 3, mRNA. / Q86YQ8* / copine 8*ENSMUSG0000005256050
Cpne5 / Q8JZW4 / Copine-5 / Q9HCH3*ENSMUSG0000002400849
Cpne9 / copine family member 9 / Q8IYJ1*ENSMUSG0000003027046


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR002035  von Willebrand factor, type A
 IPR010734  Copine
 IPR035892  C2 domain superfamily
 IPR036465  von Willebrand factor A-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006508 proteolysis ISO
 biological_processGO:0010629 negative regulation of gene expression ISO
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling ISO
 biological_processGO:0043392 negative regulation of DNA binding ISO
 biological_processGO:0045666 positive regulation of neuron differentiation ISS
 biological_processGO:0051897 positive regulation of protein kinase B signaling ISS
 biological_processGO:0071277 cellular response to calcium ion ISO
 biological_processGO:1901223 negative regulation of NIK/NF-kappaB signaling ISO
 biological_processGO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway ISO
 biological_processGO:1990138 neuron projection extension ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane ISO
 cellular_componentGO:0031965 nuclear membrane IEA
 molecular_functionGO:0001786 phosphatidylserine binding ISO
 molecular_functionGO:0004175 endopeptidase activity ISO
 molecular_functionGO:0005509 calcium ion binding ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0051059 NF-kappaB binding ISO


Pathways (from Reactome)
Pathway description
Glycerophospholipid biosynthesis
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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