ENSMUSG00000078937


Mus musculus

Features
Gene ID: ENSMUSG00000078937
  
Biological name :Cpt1b
  
Synonyms : Carnitine O-palmitoyltransferase 1, muscle isoform / Cpt1b / Q924X2
  
Possible biological names infered from orthology : carnitine palmitoyltransferase 1B / Q92523
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: E3
Gene start: 89416405
Gene end: 89425863
  
Corresponding Affymetrix probe sets: 10431564 (MoGene1.0st)   1418328_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000128188
Ensembl peptide - ENSMUSP00000129786
Ensembl peptide - ENSMUSP00000104936
NCBI entrez gene - 12895     See in Manteia.
MGI - MGI:1098297
RefSeq - NM_009948
RefSeq Peptide - NP_034078
swissprot - Q924X2
swissprot - E9Q393
swissprot - F6QXT4
Ensembl - ENSMUSG00000078937
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cpt1bENSDARG00000058285Danio rerio
 CPT1BENSG00000205560Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cpt1a / P97742 / Carnitine O-palmitoyltransferase 1, liver isoform / P50416* / carnitine palmitoyltransferase 1A*ENSMUSG0000002490062
Cpt1c / Q8BGD5 / Mus musculus carnitine palmitoyltransferase 1c (Cpt1c), transcript variant 3, mRNA. / Q8TCG5* / carnitine palmitoyltransferase 1C*ENSMUSG0000000778352
Chat / choline O-acetyltransferase / P28329*ENSMUSG0000002191924
Crat / P47934 / carnitine acetyltransferase / P43155* / carnitine O-acetyltransferase*ENSMUSG0000002685324
Crot / Q9DC50 / Peroxisomal carnitine O-octanoyltransferase / Q9UKG9* / carnitine O-octanoyltransferase*ENSMUSG0000000362323


Protein motifs (from Interpro)
Interpro ID Name
 IPR000542  Acyltransferase ChoActase/COT/CPT
 IPR032476  Carnitine O-palmitoyltransferase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006635 fatty acid beta-oxidation IEA
 biological_processGO:0015909 long-chain fatty acid transport IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005741 mitochondrial outer membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004095 carnitine O-palmitoyltransferase activity TAS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA


Pathways (from Reactome)
Pathway description
Import of palmitoyl-CoA into the mitochondrial matrix
Signaling by Retinoic Acid


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011049 impaired adaptive thermogenesis "inability or reduced ability to produce heat in response to short term environmental changes, such as stress, diet or reduced temperature, often resulting in metabolic inefficiency or death" [MGI:csmith, PMID:16836744]
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Allelic Composition: Sncatm1Nbm/Sncatm1Nbm,Tg(SNCA*A53T)1Nbm/Tg(SNCA*A53T)1Nbm,Tg(SNCA*A53T)2Nbm/Tg(SNCA*A53T)2Nbm
Genetic Background: involves: 129S6/SvEvTac * FVB/N

 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
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Allelic Composition: Eya1tm1Rilm/Eya1+,Pax2tm1Pgr/Pax2+,Six1tm1Mair/Six1+
Genetic Background: involves: 129/Sv * 129S1/Sv * 129X1/SvJ * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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