ENSMUSG00000116048


Mus musculus

Features
Gene ID: ENSMUSG00000116048
  
Biological name :Sept2
  
Synonyms : P42208 / Sept2 / Septin-2
  
Possible biological names infered from orthology : Q15019
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: D
Gene start: 93478993
Gene end: 93509733
  
Corresponding Affymetrix probe sets: 10348817 (MoGene1.0st)   1423472_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000127276
Ensembl peptide - ENSMUSP00000132850
Ensembl peptide - ENSMUSP00000136366
NCBI entrez gene - 18000     See in Manteia.
MGI - MGI:97298
RefSeq - XM_011247934
RefSeq - NM_001159717
RefSeq - NM_001159718
RefSeq - NM_001159719
RefSeq - NM_010891
RefSeq - XM_006529240
RefSeq - XM_006529241
RefSeq - XM_006529242
RefSeq Peptide - NP_035021
RefSeq Peptide - NP_001153189
RefSeq Peptide - NP_001153190
RefSeq Peptide - NP_001153191
swissprot - P42208
swissprot - E9Q3V6
Ensembl - ENSMUSG00000116048
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sept2ENSDARG00000027590Danio rerio
 SEPT2ENSGALG00000005809Gallus gallus
 SEPT2ENSG00000168385Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Sept2 / P42208 / septin 2 / Q15019*ENSMUSG00000026276100
Sept4 / P28661 / Septin-4 / O43236*ENSMUSG0000002048660
Sept5 / Q9Z2Q6 / Septin-5 / Q99719* / AC000093.1*ENSMUSG0000007221458
Sept1 / P42209 / Septin-1 ENSMUSG0000000048656
Sept7 / septin-7 isoform 2 / Q16181* / septin 7*ENSMUSG0000000183355
Sept9 / Q80UG5 / Septin-9 / Q9UHD8*ENSMUSG0000005924840
Sept3 / Q9Z1S5 / Neuronal-specific septin-3 / Q9UH03* / septin 3*ENSMUSG0000002245639
Sept12 / septin 12 / Q8IYM1*ENSMUSG0000002254231


Protein motifs (from Interpro)
Interpro ID Name
 IPR008113  Septin 2
 IPR016491  Septin
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030379  Septin-type guanine nucleotide-binding (G) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002036 regulation of L-glutamate import across plasma membrane IDA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007224 smoothened signaling pathway IMP
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0032880 regulation of protein localization IMP
 biological_processGO:0050790 regulation of catalytic activity IEA
 biological_processGO:0051258 protein polymerization TAS
 biological_processGO:0051301 cell division IEA
 biological_processGO:0060271 cilium assembly IMP
 biological_processGO:0061640 cytoskeleton-dependent cytokinesis NAS
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005826 actomyosin contractile ring NAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005876 spindle microtubule TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005930 axoneme ISO
 cellular_componentGO:0005938 cell cortex ISS
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0015629 actin cytoskeleton TAS
 cellular_componentGO:0015630 microtubule cytoskeleton TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030496 midbody TAS
 cellular_componentGO:0031105 septin complex ISO
 cellular_componentGO:0032154 cleavage furrow IEA
 cellular_componentGO:0032391 photoreceptor connecting cilium ISO
 cellular_componentGO:0035869 ciliary transition zone IDA
 cellular_componentGO:0042995 cell projection IDA
 cellular_componentGO:0043209 myelin sheath IDA
 cellular_componentGO:0045202 synapse IDA
 cellular_componentGO:0060170 ciliary membrane IEA
 cellular_componentGO:0097227 sperm annulus ISO
 cellular_componentGO:0097730 non-motile cilium ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0030234 enzyme regulator activity IDA
 molecular_functionGO:0032947 protein-containing complex scaffold activity IDA
 molecular_functionGO:0042802 identical protein binding TAS
 molecular_functionGO:0045296 cadherin binding ISO


Pathways (from Reactome)
Pathway description
Anchoring of the basal body to the plasma membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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