ENSDARG00000003706


Danio rerio

Features
Gene ID: ENSDARG00000003706
  
Biological name :ryr2b
  
Synonyms : ryanodine receptor 2b (cardiac) / ryr2b
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 17
Strand: -1
Band:
Gene start: 20009132
Gene end: 20118244
  
Corresponding Affymetrix probe sets: Dr.18896.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000125063
Ensembl peptide - ENSDARP00000134589
swissprot - A0A0R4IKT8
swissprot - F8W5K5
ZFIN ID - ZDB-GENE-061226-3
Ensembl - ENSDARG00000003706
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RYR2 / ryanodine receptor 2 / Q92736*ENSDARG0000009885658
ryr1a / ryanodine receptor 1a (skeletal) / RYR1* / P21817* / E9PZQ0* / ryanodine receptor 1*ENSDARG0000001142256
ryr1b / ryanodine receptor 1b (skeletal) / RYR1* / P21817* / ryanodine receptor 1*ENSDARG0000002379756
ryr3 / ryanodine receptor 3 / A2AGL3* / Q15413*ENSDARG0000007133156
itpr1a / inositol 1,4,5-trisphosphate receptor, type 1a / ITPR1* / P11881* / Q14643* / inositol 1,4,5-trisphosphate receptor type 1*ENSDARG0000001465512
itpr1b / inositol 1,4,5-trisphosphate receptor, type 1b / ITPR1* / P11881* / Q14643* / inositol 1,4,5-trisphosphate receptor type 1*ENSDARG0000007414912
itpr3 / inositol 1,4,5-trisphosphate receptor, type 3 / P70227* / Q14573*ENSDARG0000006174111
itpr2 / inositol 1,4,5-trisphosphate receptor, type 2 / Q14571* / Q9Z329*ENSDARG000000119098
CABZ01083778.1ENSDARG000001154243
FO834850.1 / ITPR2* / Q14571* / inositol 1,4,5-trisphosphate receptor type 2*ENSDARG000001112612


Protein motifs (from Interpro)
Interpro ID Name
 IPR000699  RIH domain
 IPR001870  B30.2/SPRY domain
 IPR002048  EF-hand domain
 IPR003032  Ryanodine receptor Ryr
 IPR003877  SPRY domain
 IPR005821  Ion transport domain
 IPR009460  Ryanodine Receptor TM 4-6
 IPR011992  EF-hand domain pair
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR013333  Ryanodine receptor
 IPR013662  RyR/IP3R Homology associated domain
 IPR014821  Inositol 1,4,5-trisphosphate/ryanodine receptor
 IPR015925  Ryanodine receptor-related
 IPR016093  MIR motif


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0006874 cellular calcium ion homeostasis IEA
 biological_processGO:0051209 release of sequestered calcium ion into cytosol IBA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 cellular_componentGO:0005623 cell IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005219 ryanodine-sensitive calcium-release channel activity IEA
 molecular_functionGO:0005262 calcium channel activity IEA
 molecular_functionGO:0005509 calcium ion binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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