ENSDARG00000071331


Danio rerio

Features
Gene ID: ENSDARG00000071331
  
Biological name :ryr3
  
Synonyms : ryanodine receptor 3 / ryr3
  
Possible biological names infered from orthology : A2AGL3 / Q15413
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 29268444
Gene end: 29420713
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000116678
Ensembl peptide - ENSDARP00000131111
swissprot - A0A0R4IA72
swissprot - Q5RGQ4
ZFIN ID - ZDB-GENE-041001-165
Ensembl - ENSDARG00000071331
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RYR3ENSGALG00000009705Gallus gallus
 RYR3ENSG00000198838Homo sapiens
 Ryr3ENSMUSG00000057378Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ryr1a / ryanodine receptor 1a (skeletal) / RYR1* / P21817* / E9PZQ0* / ryanodine receptor 1*ENSDARG0000001142264
ryr1b / ryanodine receptor 1b (skeletal) / RYR1* / P21817* / ryanodine receptor 1*ENSDARG0000002379764
RYR2 / ryanodine receptor 2 / Q92736*ENSDARG0000009885657
ryr2b / ryanodine receptor 2b (cardiac)ENSDARG0000000370654
itpr1a / inositol 1,4,5-trisphosphate receptor, type 1a / ITPR1* / P11881* / Q14643* / inositol 1,4,5-trisphosphate receptor type 1*ENSDARG0000001465513
itpr1b / inositol 1,4,5-trisphosphate receptor, type 1b / ITPR1* / P11881* / Q14643* / inositol 1,4,5-trisphosphate receptor type 1*ENSDARG0000007414913
itpr3 / inositol 1,4,5-trisphosphate receptor, type 3 / P70227* / Q14573*ENSDARG0000006174112
itpr2 / inositol 1,4,5-trisphosphate receptor, type 2 / Q14571* / Q9Z329*ENSDARG000000119099
CABZ01083778.1ENSDARG000001154245
FO834850.1 / ITPR2* / Q14571* / inositol 1,4,5-trisphosphate receptor type 2*ENSDARG000001112612


Protein motifs (from Interpro)
Interpro ID Name
 IPR000699  RIH domain
 IPR001870  B30.2/SPRY domain
 IPR002048  EF-hand domain
 IPR003032  Ryanodine receptor Ryr
 IPR003877  SPRY domain
 IPR005821  Ion transport domain
 IPR009460  Ryanodine Receptor TM 4-6
 IPR011992  EF-hand domain pair
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR013333  Ryanodine receptor
 IPR013662  RyR/IP3R Homology associated domain
 IPR014821  Inositol 1,4,5-trisphosphate/ryanodine receptor
 IPR015925  Ryanodine receptor-related
 IPR016093  MIR motif


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0006874 cellular calcium ion homeostasis IEA
 biological_processGO:0051209 release of sequestered calcium ion into cytosol IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 cellular_componentGO:0005623 cell IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005219 ryanodine-sensitive calcium-release channel activity IEA
 molecular_functionGO:0005262 calcium channel activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Stimuli-sensing channels
Ion homeostasis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0009116 slow muscle cell slow muscle cell decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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