ENSDARG00000003749
Danio rerio dna polb polymerase x domain via replacement pathway family repair activity patch resolution ap sites beta-like dna-directed binding beta membrane long base excision single-nucleotide helix-hairpin-helix dna-binding motif class n-terminal lambda fingers
Features Gene ID: ENSDARG00000003749 Biological name :polb Synonyms : polb / polymerase (DNA directed), beta Possible biological names infered from orthology : DNA polymerase beta / P06746 / Q8K409 Species: Danio rerio Chr. number: 8 Strand: 1 Band: Gene start: 2456854 Gene end: 2469761 Corresponding Affymetrix probe sets: Cross references: Ensembl peptide - ENSDARP00000017489 Ensembl peptide - ENSDARP00000118132 NCBI entrez gene - 554204
See in Manteia .
RefSeq - NM_001003879 RefSeq Peptide - NP_001003879 swissprot - B0R195 swissprot - B0R194 ZFIN ID - ZDB-GENE-040830-1 Ensembl - ENSDARG00000003749
See expression report in BioGPS See gene description in Wikigenes See co-cited genes in PubMed Ortholog prediction (from Ensembl )
Paralog prediction (from Ensembl ) poll / polymerase (DNA directed), lambda / Q9QXE2* / Q9UGP5* / DNA polymerase lambda* ENSDARG00000039613 33 polm / polymerase (DNA directed), mu / Q9JIW4* / Q9NP87* / DNA polymerase mu* ENSDARG00000103470 25 dntt / deoxynucleotidyltransferase, terminal / P04053* / DNA nucleotidylexotransferase* ENSDARG00000104792 24
Protein motifs (from Interpro ) IPR002008 DNA polymerase family X, beta-like IPR002054 DNA-directed DNA polymerase X IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 IPR010996 DNA polymerase beta-like, N-terminal domain IPR018944 DNA polymerase lambda, fingers domain IPR019843 DNA polymerase family X, binding site IPR022312 DNA polymerase family X IPR028207 DNA polymerase beta, palm domain IPR029398 DNA polymerase beta, thumb domain
Gene Ontology (GO ) nitrogen compound metabolic process response to stress cellular metabolic process primary metabolic process organic substance metabolic process cellular response to stimulus biosynthetic process nitrogen compound metabolic process response to stress cellular metabolic process primary metabolic process organic substance metabolic process cellular response to stimulus biosynthetic process nitrogen compound metabolic process response to stress cellular metabolic process primary metabolic process organic substance metabolic process cellular response to stimulus biosynthetic process nitrogen compound metabolic process response to stress cellular metabolic process primary metabolic process organic substance metabolic process cellular response to stimulus biosynthetic process nitrogen compound metabolic process response to stress cellular metabolic process primary metabolic process organic substance metabolic process cellular response to stimulus biosynthetic process nitrogen compound metabolic process response to stress cellular metabolic process primary metabolic process organic substance metabolic process cellular response to stimulus biosynthetic process nitrogen compound metabolic process response to stress cellular metabolic process primary metabolic process organic substance metabolic process cellular response to stimulus biosynthetic process nitrogen compound metabolic process response to stress cellular metabolic process primary metabolic process organic substance metabolic process cellular response to stimulus biosynthetic process nitrogen compound metabolic process response to stress cellular metabolic process primary metabolic process organic substance metabolic process cellular response to stimulus biosynthetic process nitrogen compound metabolic process response to stress cellular metabolic process primary metabolic process organic substance metabolic process cellular response to stimulus biosynthetic process nitrogen compound menitrogen compound metabolic process response to stressresponse to stress cellular metabolic pcellular metabolic process primary metabolic prprimary metabolic process organic substance meorganic substance metabolic process cellular response tocellular response to stimulus biosynthetic processbiosynthetic process organic cyclic compound binding heterocyclic compound binding catalytic activity, acting on DNA transferase activity organic cyclic compound binding heterocyclic compound binding catalytic activity, acting on DNA transferase activity organic cyclic compound binding heterocyclic compound binding catalytic activity, acting on DNA transferase activity organic cyclic compound binding heterocyclic compound binding catalytic activity, acting on DNA transferase activity organic cyclic compound binding heterocyclic compound binding catalytic activity, acting on DNA transferase activity organic cyclic compound binding heterocyclic compound binding catalytic activity, acting on DNA transferase activity organic cyclic compound binding heterocyclic compound binding catalytic activity, acting on DNA transferase activity organic cyclic compound binding heterocyclic compound binding catalytic activity, acting on DNA transferase activity organic cyclic compound binding heterocyclic compound binding catalytic activity, acting on DNA transferase activity organic cyclic compound binding heterocyclic compound binding catalytic activity, acting on DNA transferase activity organic cyclic compound bindingorganic cyclic compound binding heterocyclic compound bindingheterocyclic compound binding catalytic activity, acting on DNAcatalytic activity, acting on DNA transferase activitytransferase activity cell organelle membrane cell organelle membrane cell organelle membrane cell organelle membrane cell organelle membrane cell organelle membrane cell organelle membrane cell organelle membrane cell organelle membrane cell organelle membrane cellcell organelleorganelle membranemembrane
Pathways (from Reactome )
Phenotype (from MGI , Zfin or HPO ) ZFA:0000112 gut gut quality , abnormal gut hypoplastic , abnormal
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ZFA:0001094 whole organism whole organism viability , abnormal
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ZFA:0001114 head head decreased width , abnormal
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ZFA:0001439 anatomical system anatomical system quality , abnormal
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Interacting proteins (from Reactome ) ENSDARG00000019529 parp1 / poly (ADP-ribose) polymerase 1 / P09874* / poly (ADP-ribose) polymerase family, member 1* / complex / reaction ENSDARG00000018061 neil1 / nei-like DNA glycosylase 1 / Q8K4Q6* / Q96FI4* / Endonuclease 8-like 1 * / complex / reaction ENSDARG00000011404 fen1 / Q6TNU4 / flap structure-specific endonuclease 1 / P39748* / complex / reaction ENSDARG00000009494 xrcc1 / X-ray repair complementing defective repair in Chinese hamster cells 1 / P18887* / Q60596* / X-ray repair cross complementing 1* / complex / reaction ENSDARG00000003938 rpa1 / Q6NY74 / replication protein A1 / Q8VEE4* / P27694* / Replication protein A 70 kDa DNA-binding subunit * / reaction ENSDARG00000052553 lig3 / ligase III, DNA, ATP-dependent / P49916* / DNA ligase 3* / complex / reaction ENSDARG00000027689 pold1 / polymerase (DNA directed), delta 1, catalytic subunit / P28340* / P52431* / DNA polymerase delta 1, catalytic subunit* / reaction ENSDARG00000037188 rpa2 / replication protein A2 / RPA4* / Q13156* / P15927* / replication protein A4* / reaction ENSDARG00000060041 lig1 / ligase I, DNA, ATP-dependent / P18858* / DNA ligase 1* / complex / reaction ENSDARG00000054155 pcna / Q9PTP1 / proliferating cell nuclear antigen / P17918* / P12004* / Pcna-ps2* / reaction ENSDARG00000079632 si:dkey-28b4.7 / POLD4* / Q9CWP8* / Q9HCU8* / AP003419.1* / polymerase (DNA-directed), delta 4* / DNA polymerase delta 4, accessory subunit* / reaction ENSDARG00000100455 pnkp / polynucleotide kinase 3-phosphatase / Q96T60* / complex / reaction ENSDARG00000102645 usp47 / ubiquitin specific peptidase 47 / Q96K76* / complex
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