ENSDARG00000015068


Danio rerio

Features
Gene ID: ENSDARG00000015068
  
Biological name :txk
  
Synonyms : txk / TXK tyrosine kinase
  
Possible biological names infered from orthology : P42681 / P42682
  
Species: Danio rerio
  
Chr. number: 23
Strand: 1
Band:
Gene start: 44049509
Gene end: 44060455
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000092779
swissprot - E7F6J3
ZFIN ID - ZDB-GENE-130530-553
Ensembl - ENSDARG00000015068
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TXKENSGALG00000014127Gallus gallus
 TXKENSG00000074966Homo sapiens
 TxkENSMUSG00000054892Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tec / tec protein tyrosine kinase / P42680*ENSDARG0000009847768
btk / Bruton agammaglobulinemia tyrosine kinase / P35991* / Q06187* / Bruton tyrosine kinase* / Tyrosine-protein kinase BTK *ENSDARG0000000443358
itk / IL2 inducible T cell kinase / Q03526* / Q08881* / Tyrosine-protein kinase ITK/TSK *ENSDARG0000001756557
abl2 / c-abl oncogene 2, non-receptor tyrosine kinase / P42684* / ABL proto-oncogene 2, non-receptor tyrosine kinase* / v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)*ENSDARG0000001384141
abl1 / c-abl oncogene 1, non-receptor tyrosine kinase / P00519* / P00520* / ABL proto-oncogene 1, non-receptor tyrosine kinase*ENSDARG0000003518741
csk / C-terminal Src kinase / P41240* / P41241* / Tyrosine-protein kinase CSK *ENSDARG0000006799641
fer / fer (fps/fes related) tyrosine kinase / P70451* / P16591* / FER tyrosine kinase* / Tyrosine-protein kinase Fer *ENSDARG0000001219640
fes / FES proto-oncogene, tyrosine kinase / P07332* / P16879* / Tyrosine-protein kinase Fes/Fps *ENSDARG0000001144939
matk / megakaryocyte-associated tyrosine kinase / P42679*ENSDARG0000007467039


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR008266  Tyrosine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site
 IPR020635  Tyrosine-protein kinase, catalytic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0038083 peptidyl-tyrosine autophosphorylation IBA
 biological_processGO:0042127 regulation of cell proliferation IBA
 biological_processGO:0045087 innate immune response IBA
 cellular_componentGO:0031234 extrinsic component of cytoplasmic side of plasma membrane IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0004715 non-membrane spanning protein tyrosine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
FCERI mediated Ca+2 mobilization


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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