Manteia

ENSDARG00000016364

Danio rerio

Features

Gene ID:	ENSDARG00000016364

Biological name :	gna15.1

Synonyms :	gna15.1 / guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 1

Possible biological names infered from orthology :	GNA15 / G protein subunit alpha 15 / guanine nucleotide binding protein, alpha 15 / P30678 / P30679

Species:	Danio rerio

Chr. number:	22
Strand:	1
Band:
Gene start:	22021936
Gene end:	22036307

Corresponding Affymetrix probe sets:

Cross references:	Ensembl peptide - ENSDARP00000123739 NCBI entrez gene - 445232 See in Manteia. RefSeq - XM_005170449 swissprot - F1QJL5 ZFIN ID - ZDB-GENE-040801-146 Ensembl - ENSDARG00000016364

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
GNA15	ENSG00000060558	Homo sapiens
Gna15	ENSMUSG00000034792	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
gna15.2 / gna15.3 / guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 2 / GNA15* / P30679* / P30678* / G protein subunit alpha 15* / guanine nucleotide b...	ENSDARG00000056654	67
gnaq / guanine nucleotide binding protein (G protein), q polypeptide / P50148* / P21279* / G protein subunit alpha q* / guanine nucleotide binding protein, alpha q polypeptide*	ENSDARG00000011487	57
gna11b / guanine nucleotide binding protein (G protein), alpha 11b (Gq class)	ENSDARG00000053326	56
gna11a / guanine nucleotide binding protein (G protein), alpha 11a (Gq class)	ENSDARG00000010002	55
gna14 / guanine nucleotide binding protein (G protein), alpha 14	ENSDARG00000035178	54
gna14a / guanine nucleotide binding protein (G protein), alpha 14a / GNA14* / P30677* / O95837* / G protein subunit alpha 14* / guanine nucleotide binding protein, alpha 14*	ENSDARG00000025013	53
gnai2b / guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b / GNAI2* / P08752* / P04899* / G protein subunit alpha i2* / guanine nucleotide binding pro...	ENSDARG00000017294	45
gnai2a / guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a / GNAI2* / P08752* / P04899* / G protein subunit alpha i2* / guanine nucleotide binding pro...	ENSDARG00000018174	44
gnaia / guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a	ENSDARG00000044760	44
gnao1a / guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a / GNAO1* / P18872* / P09471* / G protein subunit alpha o1* / guanine nucleotide binding p...	ENSDARG00000016676	43
gnai1 / guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1	ENSDARG00000021647	43
gnai3 / guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 / GNAI1* / B2RSH2* / P08754* / P63096* / Q9DC51* / G protein subunit alpha i1* / G protein su...	ENSDARG00000030644	43
gnao1b / guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b / GNAO1* / P18872* / P09471* / G protein subunit alpha o1* / guanine nucleotide binding p...	ENSDARG00000036058	43
gna13b / guanine nucleotide binding protein (G protein), alpha 13b / GNA13* / Q14344* / G protein subunit alpha 13*	ENSDARG00000037924	43
gnat1 / guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 / P20612* / P11488* / G protein subunit alpha transducin 1* / guanine nucleotide binding pro...	ENSDARG00000044199	41
gna13a / guanine nucleotide binding protein (G protein), alpha 13a / GNA13* / Q14344* / P27601* / G protein subunit alpha 13* / guanine nucleotide binding protein, alpha 13*	ENSDARG00000073765	41
gnav1 / guanine nucleotide binding protein (G protein) alpha v1	ENSDARG00000043006	40
GNAZ / G protein subunit alpha z / P19086*	ENSDARG00000099844	40
gnat2 / guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 / P50149* / P19087* / G protein subunit alpha transducin 2* / guanine nucleotide binding pro...	ENSDARG00000042529	39
gna12a / guanine nucleotide binding protein (G protein) alpha 12a / GNA12* / Q03113* / P27600* / G protein subunit alpha 12* / guanine nucleotide binding protein, alpha 12*	ENSDARG00000025826	38

Protein motifs (from Interpro)

Interpro ID	Name
IPR000654	G-protein alpha subunit, group Q
IPR001019	Guanine nucleotide binding protein (G-protein), alpha subunit
IPR011025	G protein alpha subunit, helical insertion
IPR027417	P-loop containing nucleoside triphosphate hydrolase

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0007165	signal transduction	IEA
biological_process	GO:0007186	G-protein coupled receptor signaling pathway	IEA
biological_process	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway	IBA
biological_process	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway	IBA
cellular_component	GO:0005834	heterotrimeric G-protein complex	IBA
molecular_function	GO:0000166	nucleotide binding	IEA
molecular_function	GO:0001664	G-protein coupled receptor binding	IEA
molecular_function	GO:0003924	GTPase activity	IBA
molecular_function	GO:0004871	obsolete signal transducer activity	IBA
molecular_function	GO:0005525	GTP binding	IEA
molecular_function	GO:0019001	guanyl nucleotide binding	IEA
molecular_function	GO:0031683	G-protein beta/gamma-subunit complex binding	IBA

Pathways (from Reactome)

Pathway description

G alpha (q) signalling events

ADP signalling through P2Y purinoceptor 1

Thromboxane signalling through TP receptor

Thrombin signalling through proteinase activated receptors (PARs)

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSDARG00000060012	f2r / coagulation factor II (thrombin) receptor / P25116* / P30558* / Proteinase-activated receptor 1 *	/ reaction / complex
ENSDARG00000038524	pik3r1 / phosphoinositide-3-kinase, regulatory subunit 1 (alpha) / P26450* / P27986* / phosphoinositide-3-kinase regulatory subunit 1*	/ complex / reaction
ENSDARG00000056831	gng2 / guanine nucleotide binding protein (G protein), gamma 2 / P59768* / P63213* / G protein subunit gamma 2*	/ complex / reaction
ENSDARG00000075456	pik3ca / phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha / P42336* / P42337* / Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform *	/ complex / reaction
ENSDARG00000068246	plcb3 / phospholipase C, beta 3 (phosphatidylinositol-specific) / P51432* / Q01970* / phospholipase C beta 3*	/ complex / reaction
ENSDARG00000090524	f2rl2 / coagulation factor II (thrombin) receptor-like 2 / O00254*	/ reaction / complex
ENSDARG00000079472	CABZ01071020.1 / F2RL2* / O00254* / coagulation factor II thrombin receptor like 2*	/ reaction / complex
ENSDARG00000079399	F2RL3 / si:ch211-132p1.2 / O88634* / Q96RI0* / Proteinase-activated receptor 4 * / F2R like thrombin or trypsin receptor 3*	/ reaction / complex
ENSDARG00000090381	PLCB2 / phospholipase C beta 2 / A3KGF7* / Q00722* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 *	/ complex / reaction
ENSDARG00000090454	gnb1a / Q6PH57 / guanine nucleotide binding protein (G protein), beta polypeptide 1a / GNB1* / P62873* / G protein subunit beta 1*	/ complex / reaction
ENSDARG00000019426	trioa / trio Rho guanine nucleotide exchange factor a / TRIO* / Q0KL02* / O75962* / Triple functional domain protein * / trio Rho guanine nucleotide exchange factor*	/ complex / reaction
ENSDARG00000014465	arhgef25b / Rho guanine nucleotide exchange factor (GEF) 25b / Q86VW2* / ARHGEF25* / Rho guanine nucleotide exchange factor 25* / Mus musculus Rho guanine nucleotide exchange factor (GEF) 2...	/ complex / reaction
ENSDARG00000100606	BX539336.1 / Q86VW2* / ARHGEF25* / Rho guanine nucleotide exchange factor 25*	/ complex / reaction
ENSDARG00000100786	PLCB4 / phospholipase C beta 4 / Q15147*	/ complex / reaction
ENSDARG00000105281	p2ry1 / purinergic receptor P2Y1 / P47900* / P49650* / purinergic receptor P2Y, G-protein coupled 1*	/ complex
ENSDARG00000104372	gnb1b / guanine nucleotide binding protein (G protein), beta polypeptide 1b / GNB1* / P62874* / P62873* / G protein subunit beta 1* / guanine nucleotide binding protein (G protein), beta 1*	/ complex / reaction

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr