ENSDARG00000017953
Danio rerio p tp73 dna binding regulation cartilage domain response factor dna-binding apoptotic damage class mediator activity sterile alpha motif tumour superfamily protein rna polymerase ii process cranial chromatin suppressor family -like
Features Gene ID: ENSDARG00000017953 Biological name :tp73 Synonyms : tp73 / tumor protein p73 Possible biological names infered from orthology : O15350 / Q9JJP2 / transformation related protein 73 / Trp73 Species: Danio rerio Chr. number: 8 Strand: 1 Band: Gene start: 48848200 Gene end: 48935476 Corresponding Affymetrix probe sets: Dr.24319.1.S1_at (Zebrafish Array) Cross references: Ensembl peptide - ENSDARP00000074096 Ensembl peptide - ENSDARP00000109684 Ensembl peptide - ENSDARP00000109674 NCBI entrez gene - 368221
See in Manteia .
RefSeq - XM_005167294 RefSeq - XM_009304271 swissprot - B0S577 swissprot - B0S576 ZFIN ID - ZDB-GENE-030814-2 Ensembl - ENSDARG00000017953
See expression report in BioGPS See gene description in Wikigenes See co-cited genes in PubMed Ortholog prediction (from Ensembl )
Paralog prediction (from Ensembl ) tp63 / tumor protein p63 / Trp63* / Q9H3D4* / O88898* / transformation related protein 63* ENSDARG00000044356 48 tp53 / P79734 / tumor protein p53 / Trp53* / P04637* / P02340* / transformation related protein 53* ENSDARG00000035559 25
Protein motifs (from Interpro ) IPR001660 Sterile alpha motif domain IPR002117 p53 tumour suppressor family IPR008967 p53-like transcription factor, DNA-binding IPR010991 p53, tetramerisation domain IPR011615 p53, DNA-binding domain IPR012346 p53/RUNT-type transcription factor, DNA-binding domain superfamily IPR013761 Sterile alpha motif/pointed domain superfamily IPR032646 Tumour protein p73
Gene Ontology (GO ) nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process cell death response to stress cell communication cellular response to stimulus cell cycle response to abiotic stimulus regulation of molecular function anatomical structure development cellular component organization cellular component biogenesis nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process cell death response to stress cell communication cellular response to stimulus cell cycle response to abiotic stimulus regulation of molecular function anatomical structure development cellular component organization cellular component biogenesis nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process cell death response to stress cell communication cellular response to stimulus cell cycle response to abiotic stimulus regulation of molecular function anatomical structure development cellular component organization cellular component biogenesis nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process cell death response to stress cell communication cellular response to stimulus cell cycle response to abiotic stimulus regulation of molecular function anatomical structure development cellular component organization cellular component biogenesis nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process cell death response to stress cell communication cellular response to stimulus cell cycle response to abiotic stimulus regulation of molecular function anatomical structure development cellular component organization cellular component biogenesis nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process cell death response to stress cell communication cellular response to stimulus cell cycle response to abiotic stimulus regulation of molecular function anatomical structure development cellular component organization cellular component biogenesis nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process cell death response to stress cell communication cellular response to stimulus cell cycle response to abiotic stimulus regulation of molecular function anatomical structure development cellular component organization cellular component biogenesis nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process cell death response to stress cell communication cellular response to stimulus cell cycle response to abiotic stimulus regulation of molecular function anatomical structure development cellular component organization cellular component biogenesis nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process cell death response to stress cell communication cellular response to stimulus cell cycle response to abiotic stimulus regulation of molecular function anatomical structure development cellular component organization cellular component biogenesis nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process cell death response to stress cell communication cellular response to stimulus cell cycle response to abiotic stimulus regulation of molecular function anatomical structure development cellular component organization cellular component biogenesis nitrogen nitrogen compound metabolic process biosynthebiosynthetic process cellular cellular metabolic process primary mprimary metabolic process organic sorganic substance metabolic process cell deatcell death response response to stress cell commcell communication cellular cellular response to stimulus cell cyclcell cycle response response to abiotic stimulus regulatioregulation of molecular function anatomicaanatomical structure development cellular cellular component organization cellular cellular component biogenesis protein binding organic cyclic compound binding heterocyclic compound binding chromatin binding DNA-binding transcription factor activity protein binding organic cyclic compound binding heterocyclic compound binding chromatin binding DNA-binding transcription factor activity protein binding organic cyclic compound binding heterocyclic compound binding chromatin binding DNA-binding transcription factor activity protein binding organic cyclic compound binding heterocyclic compound binding chromatin binding DNA-binding transcription factor activity protein binding organic cyclic compound binding heterocyclic compound binding chromatin binding DNA-binding transcription factor activity protein binding organic cyclic compound binding heterocyclic compound binding chromatin binding DNA-binding transcription factor activity protein binding organic cyclic compound binding heterocyclic compound binding chromatin binding DNA-binding transcription factor activity protein binding organic cyclic compound binding heterocyclic compound binding chromatin binding DNA-binding transcription factor activity protein binding organic cyclic compound binding heterocyclic compound binding chromatin binding DNA-binding transcription factor activity protein binding organic cyclic compound binding heterocyclic compound binding chromatin binding DNA-binding transcription factor activity protein bindingprotein binding organic cyclic compound bindorganic cyclic compound binding heterocyclic compound bindinheterocyclic compound binding chromatin bindingchromatin binding DNA-binding transcription faDNA-binding transcription factor activity cell organelle protein-containing complex cell organelle protein-containing complex cell organelle protein-containing complex cell organelle protein-containing complex cell organelle protein-containing complex cell organelle protein-containing complex cell organelle protein-containing complex cell organelle protein-containing complex cell organelle protein-containing complex cell organelle protein-containing complex cellcell organelleorganelle protein-containing complexprotein-containing complex
Pathways (from Reactome )
Phenotype (from MGI , Zfin or HPO ) ZFA:0000008 brain brain malformed , abnormal brain decreased size , abnormal
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ZFA:0000048 olfactory placode olfactory placode morphology , abnormal
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ZFA:0000079 telencephalon telencephalon morphology , abnormal
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ZFA:0000107 eye eye decreased size , abnormal
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ZFA:0000170 basibranchial basibranchial decreased size , abnormal basibranchial undulate , abnormal
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ZFA:0000217 inner ear inner ear decreased size , abnormal
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ZFA:0001094 whole organism whole organism edematous , abnormal
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ZFA:0001114 head head morphology , abnormal
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ZFA:0001216 splanchnocranium splanchnocranium morphology , abnormal
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ZFA:0001306 pharyngeal arch pharyngeal arch malformed , abnormal
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ZFA:0001399 palatoquadrate cartilage palatoquadrate cartilage mislocalised posteriorly , abnormal
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ZFA:0001400 ceratohyal cartilage ceratohyal cartilage displaced , abnormal
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ZFA:0001422 hyosymplectic cartilage hyosymplectic cartilage mislocalised posteriorly , abnormal
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ZFA:0001458 cranial cartilage cranial cartilage shape , abnormal cranial cartilage malformed , abnormal
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ZFA:0001510 basihyal cartilage basihyal cartilage decreased size , abnormal basihyal cartilage undulate , abnormal
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ZFA:0001516 ceratobranchial cartilage ceratobranchial cartilage decreased size , abnormal
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Interacting proteins (from Reactome ) ENSDARG00000009136 tp53bp2a / tumor protein p53 binding protein, 2a / Q13625* / TP53BP2* / Trp53bp2* / tumor protein p53 binding protein 2* / transformation related protein 53 binding protein 2* / complex / reaction ENSDARG00000009142 ppp1r13bb / protein phosphatase 1, regulatory subunit 13Bb / Q96KQ4* / Q62415* / PPP1R13B* / protein phosphatase 1 regulatory subunit 13B* / protein phosphatase 1, regulatory (inhibitor) subunit 13B* / complex / reaction ENSDARG00000004377 ppp1r13ba / protein phosphatase 1, regulatory subunit 13Ba / Q96KQ4* / Q62415* / PPP1R13B* / protein phosphatase 1 regulatory subunit 13B* / protein phosphatase 1, regulatory (inhibitor) subunit 13B* / complex / reaction ENSDARG00000017953 tp73 / tumor protein p73 / Trp73* / Q9JJP2* / O15350* / transformation related protein 73* / complex ENSDARG00000068401 yap1 / Q1L8J7 / Yes-associated protein 1 / P46937* / P46938* / complex / reaction ENSDARG00000054858 tp53bp2b / tumor protein p53 binding protein, 2b / Q13625* / TP53BP2* / Trp53bp2* / tumor protein p53 binding protein 2* / transformation related protein 53 binding protein 2* / complex / reaction ENSDARG00000013777 ppp1r13l / protein phosphatase 1, regulatory subunit 13 like / Q5I1X5* / Q8WUF5* / protein phosphatase 1, regulatory (inhibitor) subunit 13 like* / complex / reaction
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