ENSDARG00000018569
Danio rerio signaling tnfrsf1a tnfr response tumor necrosis regulation domain receptor pathway membrane death superfamily factor organism bacterium neutrophil fin apoptotic integral component -induced ngfr cysteine-rich region death-like member n-terminal teleost granuloma formation
Features Gene ID: ENSDARG00000018569 Biological name :tnfrsf1a Synonyms : tnfrsf1a / Possible biological names infered from orthology : P19438 / / Species: Danio rerio Chr. number: 16 Strand: -1 Band: Gene start: 17060758 Gene end: 17072561 Corresponding Affymetrix probe sets: DrAffx.2.55.S1_at (Zebrafish Array) NM_213190_at (Zebrafish Genome Array with custom cdf files) Cross references: Ensembl peptide - ENSDARP00000011163406471
See in Manteia .
NM_213190 NP_998355 F1QQS0 ZDB-GENE-040426-2252 ENSDARG00000018569
See expression report in BioGPS See gene description in Wikigenes See co-cited genes in PubMed Ortholog prediction (from Ensembl )Paralog prediction (from Ensembl ) si:ch211-112c15.8 / Q93038* / TNFRSF25* / TNF receptor superfamily member 25* / tumor necrosis factor receptor superfamily, member 25* ENSDARG00000089868 16
Protein motifs (from Interpro ) IPR000488 Death domain IPR001368 TNFR/NGFR cysteine-rich region IPR011029 Death-like domain superfamily IPR033994 Tumor necrosis factor receptor 1A, death domain IPR033995 Tumor necrosis factor receptor superfamily member 1A, N-terminal, teleost
Gene Ontology (GO ) response to stress response to external stimulus immune effector process cell communication cellular response to stimulus anatomical structure development response to biotic stimulus response to chemical localization of cell movement of cell or subcellular component developmental growth cell death immune response response to stress response to external stimulus immune effector process cell communication cellular response to stimulus anatomical structure development response to biotic stimulus response to chemical localization of cell movement of cell or subcellular component developmental growth cell death immune response response to stress response to external stimulus immune effector process cell communication cellular response to stimulus anatomical structure development response to biotic stimulus response to chemical localization of cell movement of cell or subcellular component developmental growth cell death immune response response to stress response to external stimulus immune effector process cell communication cellular response to stimulus anatomical structure development response to biotic stimulus response to chemical localization of cell movement of cell or subcellular component developmental growth cell death immune response response to stress response to external stimulus immune effector process cell communication cellular response to stimulus anatomical structure development response to biotic stimulus response to chemical localization of cell movement of cell or subcellular component developmental growth cell death immune response response to stress response to external stimulus immune effector process cell communication cellular response to stimulus anatomical structure development response to biotic stimulus response to chemical localization of cell movement of cell or subcellular component developmental growth cell death immune response response to stress response to external stimulus immune effector process cell communication cellular response to stimulus anatomical structure development response to biotic stimulus response to chemical localization of cell movement of cell or subcellular component developmental growth cell death immune response response to stress response to external stimulus immune effector process cell communication cellular response to stimulus anatomical structure development response to biotic stimulus response to chemical localization of cell movement of cell or subcellular component developmental growth cell death immune response response to stress response to external stimulus immune effector process cell communication cellular response to stimulus anatomical structure development response to biotic stimulus response to chemical localization of cell movement of cell or subcellular component developmental growth cell death immune response response to stress response to external stimulus immune effector process cell communication cellular response to stimulus anatomical structure development response to biotic stimulus response to chemical localization of cell movement of cell or subcellular component developmental growth cell death immune response response tresponse to stress response tresponse to external stimulus immune effimmune effector process cell commucell communication cellular rcellular response to stimulus anatomicalanatomical structure development response tresponse to biotic stimulus response tresponse to chemical localizatilocalization of cell movement omovement of cell or subcellular component developmendevelopmental growth cell deathcell death immune resimmune response signaling receptor activity signaling receptor activity signaling receptor activity signaling receptor activity signaling receptor activity signaling receptor activity signaling receptor activity signaling receptor activity signaling receptor activity signaling receptor activity signaling receptor activitysignaling receptor activity cell membrane cell membrane cell membrane cell membrane cell membrane cell membrane cell membrane cell membrane cell membrane cell membrane cellcell membranemembrane
Pathways (from Reactome )Phenotype (from MGI , Zfin or HPO ) ZFA:0000037 anatomical structure anatomical structure amount , ameliorated
Show ZFA:0001094 whole organism whole organism decreased life span , abnormal
Show ZFA:0001269 regenerating fin regenerating fin macrophage decreased amount , abnormal
Show ZFA:0001270 blastema blastema cell proliferation decreased occurrence , abnormal
Show ZFA:0009141 macrophage macrophage decreased amount , abnormal
Show ZFA:0009327 neutrophil neutrophil response to bacterium process quality , abnormal
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Interacting proteins (from Reactome ) ENSDARG00000018569 tnfrsf1a / tumor necrosis factor receptor superfamily, member 1a / P19438* / P25118* / TNF receptor superfamily member 1A* / complex ENSDARG00000013598 tnfb / tumor necrosis factor b (TNF superfamily, member 2) / LTA* / TNF* / P01375* / P06804* / P09225* / P01374* / lymphotoxin A* / lymphotoxin alpha* / tumor necrosis factor* / complex / reaction ENSDARG00000036057 tradd / Q9I9N5 / tnfrsf1a-associated via death domain / Q15628* / Q3U0V2* / complex / reaction ENSDARG00000030173 traf2a / Tnf receptor-associated factor 2a / TRAF2* / P39429* / Q12933* / TNF receptor associated factor 2* / complex / reaction ENSDARG00000040523 smpd2a / sphingomyelin phosphodiesterase 2a, neutral membrane (neutral sphingomyelinase) / SMPD2* / O60906* / sphingomyelin phosphodiesterase 2* / complex / reaction ENSDARG00000051920 nsmaf / neutral sphingomyelinase (N-SMase) activation associated factor / Q92636* / neutral sphingomyelinase activation associated factor* / complex / reaction ENSDARG00000052701 smpd2b / sphingomyelin phosphodiesterase 2b, neutral membrane (neutral sphingomyelinase) / SMPD2* / O70572* / O60906* / sphingomyelin phosphodiesterase 2* / sphingomyelin phosphodiesterase ... / complex / reaction ENSDARG00000041619 rack1 / O42248 / receptor for activated C kinase 1 / P68040* / P63244* / Receptor of activated protein C kinase 1 Receptor of activated protein C kinase 1, N-terminally processed* / complex / reaction ENSDARG00000098226 smpd3 / sphingomyelin phosphodiesterase 3, neutral / Q9JJY3* / Q9NY59* / sphingomyelin phosphodiesterase 3* / complex / reaction ENSDARG00000043179 bag4 / BCL2 associated athanogene 4 / O95429* / Q8CI61* / BAG family molecular chaperone regulator 4 * / complex ENSDARG00000044619 birc2 / baculoviral IAP repeat containing 2 / BIRC3* / Q13489* / Q13490* / Q62210* / baculoviral IAP repeat containing 3* / Baculoviral IAP repeat-containing protein 2 * / complex / reaction
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