ENSDARG00000019213


Danio rerio

Features
Gene ID: ENSDARG00000019213
  
Biological name :zgc:136929
  
Synonyms : zgc:136929
  
Possible biological names infered from orthology : CTBP1 / C-terminal binding protein 1 / O88712 / Q13363
  
Species: Danio rerio
  
Chr. number: 14
Strand: 1
Band:
Gene start: 21140612
Gene end: 21199502
  
Corresponding Affymetrix probe sets: Dr.936.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000145521
Ensembl peptide - ENSDARP00000059795
Ensembl peptide - ENSDARP00000130473
Ensembl peptide - ENSDARP00000155016
NCBI entrez gene - 678649     See in Manteia.
swissprot - Q1RLQ4
ZFIN ID - ZDB-GENE-060421-4235
Ensembl - ENSDARG00000019213
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CTBP1ENSGALG00000039942Gallus gallus
 CTBP1ENSG00000159692Homo sapiens
 Ctbp1ENSMUSG00000037373Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ctbp1 / C-terminal binding protein 1ENSDARG0000005700780
ctbp2a / C-terminal binding protein 2a / CTBP2* / P56545* / P56546* / C-terminal binding protein 2*ENSDARG0000004406278
phgdh / phosphoglycerate dehydrogenase / O43175* / Q61753* / D-3-phosphoglycerate dehydrogenase *ENSDARG0000000187323


Protein motifs (from Interpro)
Interpro ID Name
 IPR006139  D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
 IPR006140  D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain
 IPR016040  NAD(P)-binding domain
 IPR029752  D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1
 IPR029753  D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:1903507 negative regulation of nucleic acid-templated transcription IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0003714 transcription corepressor activity IBA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
 molecular_functionGO:0016618 hydroxypyruvate reductase activity IBA
 molecular_functionGO:0030267 glyoxylate reductase (NADP) activity IBA
 molecular_functionGO:0042803 protein homodimerization activity IBA
 molecular_functionGO:0051287 NAD binding IEA


Pathways (from Reactome)
Pathway description
SUMOylation of transcription cofactors
Repression of WNT target genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000007438 ube2ib / Q9W6H5 / ubiquitin-conjugating enzyme E2Ib / UBE2I* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction
 ENSDARG00000044267 sumo1 / Q7SZR5 / small ubiquitin-like modifier 1 / P63166* / P63165* / Small ubiquitin-related modifier 1 *  / reaction / complex
 ENSDARG00000028119 Q6NV25 / sumo3a / small ubiquitin-like modifier 3a / SUMO3* / Q9Z172* / P55854* / small ubiquitin-like modifier 3*  / reaction
 ENSDARG00000035993 sumo3b / small ubiquitin-like modifier 3b / SUMO3* / P55854* / small ubiquitin-like modifier 3*  / reaction
 ENSDARG00000052649 Q9DDJ0 / ube2ia / ubiquitin-conjugating enzyme E2Ia / UBE2I* / P63280* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction
 ENSDARG00000102741 sumo2b / Q6DHL4 / small ubiquitin-like modifier 2b / SUMO4* / SUMO2* / Q6EEV6* / P61956* / P61957* / small ubiquitin-like modifier 4* / small ubiquitin-like modifier 2*  / reaction






 

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