ENSDARG00000028119


Danio rerio

Features
Gene ID: ENSDARG00000028119
  
Biological name :sumo3a
  
Synonyms : Q6NV25 / small ubiquitin-like modifier 3a / sumo3a
  
Possible biological names infered from orthology : P55854 / Q9Z172 / small ubiquitin-like modifier 3 / SUMO3
  
Species: Danio rerio
  
Chr. number: 6
Strand: -1
Band:
Gene start: 11070261
Gene end: 11073880
  
Corresponding Affymetrix probe sets: Dr.1291.1.S1_at (Zebrafish Array)   NM_213124_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000035513
NCBI entrez gene - 406398     See in Manteia.
RefSeq - NM_213124
RefSeq Peptide - NP_998289
swissprot - Q6NV25
ZFIN ID - ZDB-GENE-040426-2133
Ensembl - ENSDARG00000028119
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SUMO3ENSGALG00000032783Gallus gallus
 SUMO3ENSG00000184900Homo sapiens
 Sumo3ENSMUSG00000112241Mus musculus
 Sumo3ENSMUSG00000020265Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sumo3b / small ubiquitin-like modifier 3b / SUMO3* / P55854* / small ubiquitin-like modifier 3*ENSDARG0000003599399
sumo2b / Q6DHL4 / small ubiquitin-like modifier 2b / SUMO4* / SUMO2* / Q6EEV6* / P61956* / P61957* / small ubiquitin-like modifier 4* / small ubiquitin-like modifier 2*ENSDARG0000010274193
sumo2a / small ubiquitin-like modifier 2aENSDARG0000010439066
sumo1 / Q7SZR5 / small ubiquitin-like modifier 1 / P63166* / P63165* / Small ubiquitin-related modifier 1 *ENSDARG0000004426750


Protein motifs (from Interpro)
Interpro ID Name
 IPR000626  Ubiquitin domain
 IPR022617  Rad60/SUMO-like domain
 IPR029071  Ubiquitin-like domain superfamily
 IPR033950  Sumo domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016925 protein sumoylation IBA
 biological_processGO:0043009 chordate embryonic development IGI
 biological_processGO:0060216 definitive hemopoiesis IGI
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016605 PML body IEA
 molecular_functionGO:0031386 protein tag IBA


Pathways (from Reactome)
Pathway description
SUMO is proteolytically processed
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription factors
SUMOylation of transcription cofactors
SUMOylation of intracellular receptors
SUMOylation of chromatin organization proteins
SUMOylation of DNA replication proteins
Formation of Incision Complex in GG-NER


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000000151 thraa / Q98867 / thyroid hormone receptor alpha a / THRA* / P63058* / P10827* / thyroid hormone receptor, alpha*  / reaction
 ENSDARG00000021163 thrb / Q9PVE4 / thyroid hormone receptor beta / P10828* / P37242*  / reaction
 ENSDARG00000019529 parp1 / poly (ADP-ribose) polymerase 1 / P09874* / poly (ADP-ribose) polymerase family, member 1*  / reaction
 ENSDARG00000007438 ube2ib / Q9W6H5 / ubiquitin-conjugating enzyme E2Ib / UBE2I* / P63279* / ubiquitin conjugating enzyme E2 I*  / complex / reaction
 ENSDARG00000014329 npm1a / nucleophosmin 1a / NPM1* / Q61937* / P06748* / nucleophosmin 1*  / reaction
 ENSDARG00000007198 mta1 / metastasis associated 1 / Q13330* / Q8K4B0* / Mus musculus metastasis associated 1 (Mta1), transcript variant 2, mRNA.*  / reaction
 ENSDARG00000035559 tp53 / P79734 / tumor protein p53 / Trp53* / P04637* / P02340* / transformation related protein 53*  / reaction
 ENSDARG00000028119 Q6NV25 / sumo3a / small ubiquitin-like modifier 3a / SUMO3* / Q9Z172* / P55854* / small ubiquitin-like modifier 3*  / reaction
 ENSDARG00000035993 sumo3b / small ubiquitin-like modifier 3b / SUMO3* / P55854* / small ubiquitin-like modifier 3*  / reaction
 ENSDARG00000039754 xpc / xeroderma pigmentosum, complementation group C / P51612* / Q01831* / XPC complex subunit, DNA damage recognition and repair factor*  / complex
 ENSDARG00000021550 rad23b / RAD23 homolog B, nucleotide excision repair protein / P54727*  / complex
 ENSDARG00000101510 cetn2 / centrin, EF-hand protein, 2 / CETN1* / Q9R1K9* / P41209* / Q12798* / P41208* / centrin 2* / centrin 1*  / complex / reaction
 ENSDARG00000003938 rpa1 / Q6NY74 / replication protein A1 / Q8VEE4* / P27694* / Replication protein A 70 kDa DNA-binding subunit *  / reaction
 ENSDARG00000060646 senp5 / SUMO1/sentrin specific peptidase 5 / Q6NXL6* / Q96HI0* / Sentrin-specific protease 5 *  / reaction
 ENSDARG00000029766 nr1i2 / nuclear receptor subfamily 1, group I, member 2 / O54915* / O75469*  / reaction
 ENSDARG00000019213 zgc:136929 / CTBP1* / O88712* / Q13363* / C-terminal binding protein 1*  / reaction
 ENSDARG00000061885 satb2 / SATB homeobox 2 / Q8VI24* / Q9UPW6* / special AT-rich sequence binding protein 2*  / reaction
 ENSDARG00000052649 Q9DDJ0 / ube2ia / ubiquitin-conjugating enzyme E2Ia / UBE2I* / P63280* / P63279* / ubiquitin conjugating enzyme E2 I*  / complex / reaction
 ENSDARG00000078574 si:dkey-21c19.3 / SENP1* / Q9P0U3* / P59110* / Sentrin-specific protease 1 * / SUMO1/sentrin specific peptidase 1*  / reaction
 ENSDARG00000073837 senp2 / SUMO1/sentrin/SMT3 specific peptidase 2 / Gm7275* / Gm5407* / Gm5415* / Q91ZX6* / Q9HC62* / AF366264* / 4930444G20Rik* / cDNA sequence AF366264* / RIKEN cDNA 4930444G20 gene* / Mus ...  / reaction
 ENSDARG00000024488 top2a / DNA topoisomerase II alpha / P11388* / Q01320* / DNA topoisomerase 2-alpha *  / reaction
 ENSDARG00000086764 mdc1 / mediator of DNA damage checkpoint 1 / Q14676*  / reaction
 ENSDARG00000052654 thrab / thyroid hormone receptor alpha b / THRA* / P63058* / P10827* / thyroid hormone receptor, alpha*  / reaction
 ENSDARG00000098439 nr1h3 / nuclear receptor subfamily 1, group H, member 3 / Q13133*  / reaction
 ENSDARG00000102741 sumo2b / Q6DHL4 / small ubiquitin-like modifier 2b / SUMO4* / SUMO2* / Q6EEV6* / P61956* / P61957* / small ubiquitin-like modifier 4* / small ubiquitin-like modifier 2*  / reaction
 ENSDARG00000098349 hdac4 / histone deacetylase 4 / P56524* / Q6NZM9*  / reaction






 

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